Search Results - "Dadon, Daniel B"

3D Chromosome Regulatory Landscape of Human Pluripotent Cells by Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.

“…In this study, we describe the 3D chromosome regulatory landscape of human naive and primed embryonic stem cells. To devise this map, we identified…”
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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system by Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf

“…Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great potential in therapeutics. We…”
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Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions by Ji, Xiong, Dadon, Daniel B., Abraham, Brian J., Lee, Tong Ihn, Jaenisch, Rudolf, Bradner, James E., Young, Richard A.

“…More than a thousand proteins are thought to contribute to mammalian chromatin and its regulation, but our understanding of the genomic occupancy and function…”
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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells by Wu, Xuebing, Scott, David A, Kriz, Andrea J, Chiu, Anthony C, Hsu, Patrick D, Dadon, Daniel B, Cheng, Albert W, Trevino, Alexandro E, Konermann, Silvana, Chen, Sidi, Jaenisch, Rudolf, Zhang, Feng, Sharp, Phillip A

“…Genome-wide analysis of Cas9-DNA interactions in mammalian cells shows widespread binding but low levels of cleavage. Bacterial type II CRISPR-Cas9 systems…”
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TALEN-mediated editing of the mouse Y chromosome by Wang, Haoyi, Hu, Yueh-Chiang, Markoulaki, Styliani, Welstead, G Grant, Cheng, Albert W, Shivalila, Chikdu S, Pyntikova, Tatyana, Dadon, Daniel B, Voytas, Daniel F, Bogdanove, Adam J, Page, David C, Jaenisch, Rudolf

“…Targeted nucleases succeed in modifying the Y chromosome that has been recalcitrant to traditional genome engineering methods. The functional study of Y…”
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