Search Results - "Dadke, Shrikrishna"

Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region by Dadke, Shrikrishna, Kusari, Jyotirmoy, Chernoff, Jonathan

“…Protein-tyrosine phosphatases (PTPs) play a major role in regulating insulin signaling. Among the PTPs that regulate this signaling pathway, PTP1B plays an…”
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Protein-tyrosine Phosphatase 1B Mediates the Effects of Insulin on the Actin Cytoskeleton in Immortalized Fibroblasts by Dadke, Shrikrishna, Chernoff, Jonathan

“…Insulin regulates diverse cellular responses including actin reorganization. The mechanism by which insulin induces formation of lamellipodia in cultured cells…”
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Elevated Expression and Activity of Protein-Tyrosine Phosphatase 1B in Skeletal Muscle of Insulin-Resistant Type II Diabetic Goto-Kakizaki Rats by Dadke, Shrikrishna S., Li, Hong C., Kusari, Anasua B., Begum, Najma, Kusari, Jyotirmoy

“…We investigated the cellular mechanism(s) of insulin resistance associated with non-insulin dependent diabetes mellitus (NIDDM) using skeletal muscles isolated…”
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A sensitive and high throughput method for the analysis of d-psicose by capillary electrophoresis by Surapureddi, Sri Rama Krishna, Kunta, Ravindhranath, Sameer Kumar, Gantasala S., Sappidi, Sreedhar Reddy, Dadke, Shrikrishna

“…•d-Psicose is quantified for the first time by capillary electrophoresis.•Obtained linear curves for all the sugars with a lower concentration ranges.•No need…”
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Regulation of protein tyrosine phosphatase 1B by sumoylation by Chernoff, Jonathan, Rauscher, Frank, Haj, Fawaz, Cotteret, Sophie, Shuai, Ke, Ng, Tony, Jaffer, Zahara M, Ivanov, Alexey, Dadke, Shrikrishna, Yip, Shu-Chin, Neel, Benjamin G

“…Protein-tyrosine phosphatase 1B (PTP1B) is an ubiquitously expressed enzyme that negatively regulates growth-factor signalling and cell proliferation by…”
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Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains by Dadke, Shrikrishna, Chernoff, Jonathan

“…We have shown previously that protein tyrosine phosphatase (PTP) 1B interacts with insulin receptor and negatively regulates insulin signalling by an…”
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Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor by Dadke, S, Kusari, A, Kusari, J

“…We have previously reported a direct in vivo interaction between the activated insulin receptor and protein-tyrosine phosphatase-1B (PTP1B), which leads to an…”
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Protein-tyrosine phosphatase 1B as a potential drug target for obesity by Dadke, Shrikrishna, Chernoff, Jonathan

“…Obesity is increasing at an alarming rate and is considered by the World Health Organization as one of the top 10 epidemics worldwide. Resistance to leptin and…”
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Insulin regulates MAP kinase phosphatase-1 induction in Hirc B cells via activation of both extracellular signal-regulated kinase (ERK) and c-Jun-N-terminal kinase (JNK) by Byon, J C, Dadke, S S, Rulli, S, Kusari, A B, Kusari, J

“…Previously, we have reported that insulin induces the expression of the dual-specificity tyrosine phosphatase Mitogen-activated protein (MAP) kinase…”
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Loss of a putative novel growth inhibitory apoptotic 14 kD polypeptide during progression of rat liver carcinogenesis by Dadke, S S, Krishnamurthy, S C, Rao, K V

“…Carcinogenesis is a multistep process involving different stages. However, the biological and biochemical factors responsible for the stepwise transition of…”
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Identification, purification and characterization of a putative novel growth-inhibitory and/or apoptotic protein from rat liver by Dadke, S S, Rao, K V

“…The existence of endogenous growth inhibitors was postulated in 1914 by Boveri. However, most regretfully, progress in the isolation, characterization and…”
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