Search Results - "Dada, Hiba"

Blood-Based Next-Generation Sequencing in Adrenocortical Carcinoma by Nazha, Bassel, Zhuang, Tony Z, Dada, Hiba I, Drusbosky, Leylah M, Brown, Jacqueline T, Ravindranathan, Deepak, Carthon, Bradley C, Kucuk, Omer, Goldman, Jamie, Master, Viraj A, Bilen, Mehmet Asim

“…Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. We aimed to evaluate the feasibility of next-generation sequencing…”
Get full text

A study on the effects of thermal treatments and gamma rays irradiation on expired “Helixone” membranes by Al Lafi, Abdul Ghaffar, Dada, Hiba, Harmalani, Hamdi

“…Polysulfones (PSF) are specialty thermoplastics that are commonly used in dialysis membranes production. In the present work, the effects of γ-rays irradiation…”
Get full text

Detection of microsatellite instability-high (MSI-H) by liquid biopsy predicts robust and durable response to immunotherapy in patients with pancreatic cancer by Chakrabarti, Sakti, Bucheit, Leslie, Starr, Jason Scott, Innis-Shelton, Racquel, Shergill, Ardaman, Dada, Hiba, Resta, Regina, Wagner, Stephanie, Fei, Naomi, Kasi, Pashtoon Murtaza

“…Clinical trials reporting the robust antitumor activity of immune checkpoint inhibitors (ICIs) in microsatellite instability-high (MSI-H) solid tumors have…”
Get full text

Clinical Outcomes for Plasma-Based Comprehensive Genomic Profiling Versus Standard-of-Care Tissue Testing in Advanced Non–Small Cell Lung Cancer by Page, Ray D., Drusbosky, Leylah M., Dada, Hiba, Raymond, Victoria M., Daniel, Davey B., Divers, Stephen G., Reckamp, Karen L., Villalona-Calero, Miguel A., Dix, Daniel, Odegaard, Justin I., Lanman, Richard B., Papadimitrakopoulou, Vassiliki A., Leighl, Natasha B.

“…: Somatic genomic testing is recommended by numerous expert guidelines to inform targeted therapy treatment for patients with advanced nonsquamous non–small…”
Get full text

Circulating Cell-Free Tumor DNA in Advanced Pancreatic Adenocarcinoma Identifies Patients With Worse Overall Survival by Botrus, Gehan, Uson Junior, Pedro Luiz Serrano, Raman, Puneet, Kaufman, Adrienne E, Kosiorek, Heidi, Yin, Jun, Fu, Yu, Majeed, Umair, Sonbol, Mohamad Bassam, Ahn, Daniel H, Chang, Isabela W, Drusbosky, Leylah M, Dada, Hiba, Starr, Jason, Borad, Mitesh, Mody, Kabir, Bekaii-Saab, Tanios S

“…Plasma-based circulating cell-free tumor DNA (ctDNA) genomic profiling by next-generation sequencing (NGS)is an emerging diagnostic tool for pancreatic cancer…”
Get full text

Cell-free circulating tumor DNA (cfDNA) analysis of advanced thymic epithelial tumors (TETs) by Dada, Hiba I., Drusbosky, Leylah, Giaccone, Giuseppe

“…Abstract only 8577 Background: Thymic epithelial tumors (TETs) are rare tumors originating from the epithelial cells of the thymus. Thymomas tend to be slowly…”
Get full text

Comprehensive landscape of BRAF variant classes, clonalities, and comutations in metastatic colorectal cancer using ctDNA profiling by Johnson, Benny, Yang, Dong, Dada, Hiba I., Drusbosky, Leylah, Kopetz, Scott

“…Abstract only 152 Background: Although BRAF V600E accounts for the majority of the BRAF mutations in mCRC, non-V600 BRAF variants have been shown in recent…”
Get full text

Circulating tumor DNA-based genomic landscape of early-onset pancreatic cancer by Barnett, Reagan, Dada, Hiba I., Drusbosky, Leylah, Clemens, Keelia, Hochster, Howard S., Gulhati, Pat

“…Abstract only 588 Background: The incidence of gastrointestinal and obesity related cancers, including pancreatic cancer, is increasing in individuals <50…”
Get full text

Genomic landscape differences in patients with advanced non-small cell lung cancer by sex and age by Kimbrough, ErinMarie, Dada, Hiba I., Drusbosky, Leylah, Zhao, Yujie, Manochakian, Rami, Lou, Yanyan

“…Abstract only 9108 Background: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related death in the U.S. The median age at diagnosis is 70…”
Get full text

The role of serial analysis of hepatocellular carcinoma via circulating tumor DNA in identification of new actionable alterations by Hsieh, David, Bucheit, Leslie A., Kasi, Pashtoon Murtaza, Beg, Muhammad Shaalan, Zhu, Hao, Dada, Hiba I., Yang, Dong

“…Abstract only 478 Background: Molecular profiling using circulating tumor DNA (ctDNA) is advantageous in cancers where tissue biopsies are not routinely…”
Get full text

Identification of pathogenic CDK12 alterations in cell-free DNA (cfDNA) from patients with breast cancer by Taylor, Mary Love, Dada, Hiba I., Florian, Hannah, Marcom, Paul Kelly, Anders, Carey K., Drusbosky, Leylah, Force, Jeremy Meyer

“…Abstract only 1028 Background: Cyclin dependent kinase 12 ( CDK12) has both tumor suppressive and proto-oncogenic potential in metastatic breast cancers (MBC)…”
Get full text

Circulating tumor DNA-based genomic profiling of small bowel adenocarcinoma by Gulhati, Pat, Pandya, Karan, Dada, Hiba I., Cogle, Christopher R., Starr, Jason S., Kalmadi, Sujith R., Braiteh, Fadi S., Drusbosky, Leylah

“…Abstract only 3523 Background: Small bowel adenocarcinoma (SBA) is a rare malignancy, with lower incidence, later stage at diagnosis, and worse overall…”
Get full text

Circulating tumor DNA (ctDNA) in patients with advanced adrenocortical carcinoma by Nazha, Bassel, Dada, Hiba I., Drusbosky, Leylah, Brown, Jacqueline T, Ravindranathan, Deepak, Carthon, Bradley Curtis, Kucuk, Omer, Master, Viraj A., Bilen, Mehmet Asim

“…Abstract only 4585 Background: Adrenocortical Carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis and limited treatments in the advanced…”
Get full text

Liquid biopsies for the front line therapy decision in non-small cell lung cancer by Brice, Kayla, Raez, Luis E., Dumais, Katerine, Wietecha, Delia, Lopez-Cohen, Alejandro, Izquierdo, Paola, Drusbosky, Leylah, Dada, Hiba I., Powery, Herman W.

“…Abstract only e21103 Background: Current literature has demonstrated non-inferiority of liquid biopsies relative to tissue genotyping to identify detectable…”
Get full text

Circulating Tumor DNA‐Based Testing and Actionable Findings in Patients with Advanced and Metastatic Pancreatic Adenocarcinoma by Botrus, Gehan, Kosirorek, Heidi, Sonbol, Mohamad Bassam, Kusne, Yael, Uson Junior, Pedro Luiz Serrano, Borad, Mitesh J., Ahn, Daniel H., Kasi, Pashtoon M., Drusbosky, Leylah M., Dada, Hiba, Surapaneni, Phani Keerthi, Starr, Jason, Ritter, Ashton, McMillan, Jessica, Wylie, Natasha, Mody, Kabir, Bekaii‐Saab, Tanios S.

“…Purpose Recent advances in molecular diagnostic technologies allow for the evaluation of solid tumor malignancies through noninvasive blood sampling, including…”
Get full text

Clinical outcomes for plasma-based comprehensive genomic profiling versus tissue testing in advanced lung adenocarcinoma by Page, Ray D., Drusbosky, Leylah, Dada, Hiba I., Raymond, Victoria M., Daniel, Davey B., Divers, Stephen G., Reckamp, Karen L., Villalona-Calero, Miguel Angel, Odegaard, Justin Iver, Lanman, Richard B., Papadimitrakopoulou, Vassiliki, Leighl, Natasha B.

“…Abstract only 9027 Background: Somatic genomic testing is recommended by numerous expert guidelines to inform targeted therapy treatment for patients with…”
Get full text

RAS co-mutation and early onset disease represent an aggressive phenotype of atypical (non-V600) BRAF mutant metastatic colorectal cancer by Johnson, Benny, Yang, Dong, Dada, Hiba I., Morris, Van K., Wang, Xuemei, Dasari, Arvind, Raghav, Kanwal Pratap Singh, Kee, Bryan K., Shen, John Paul Y.C., Huey, Ryan, Lee, Michael Sangmin, Parseghian, Christine Megerdichian, Le, Phat, Morelli, Maria Pia, Willis, Jason, Wolff, Robert A., Drusbosky, Leylah, Overman, Michael J., Kopetz, Scott

“…3592 Background: While BRAF V600E accounts for the majority of BRAF mutations in mCRC, non-V600 BRAF variants (a BRAF) have emerged in recent years as a…”
Get full text

Blood-based tumor mutational burden from circulating tumor DNA (ctDNA) across advanced solid malignancies using a commercially available liquid biopsy assay by Drusbosky, Leylah, Bilen, Mehmet Asim, Azzi, Georges, Barata, Pedro C., Boland, Patrick M, Bryce, Alan Haruo, Chae, Young Kwang, Force, Jeremy Meyer, Gutierrez, Martin, Kasi, Pashtoon Murtaza, Dada, Hiba I., Weipert, Caroline, Hensel, Chuck, Kiedrowski, Lesli A., Lee, Che-Yu, Lefterova, Martina, Gandara, David R.

“…Abstract only 3040 Background: Pembrolizumab was recently FDA approved across solid tumors for TMB scores ≥ 10mut/Mb as assessed by next-generation sequencing…”
Get full text