Search Results - "Dabrosin, Charlotta"

Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women by Lindahl, Gabriel, Abrahamsson, Annelie, Dabrosin, Charlotta

“…Background Anti-oestrogens such as tamoxifen, decrease the risk of breast cancer but are unsuitable for prevention because of their side-effects. Diet…”
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CCL2 and CCL5 Are Novel Therapeutic Targets for Estrogen-Dependent Breast Cancer by Svensson, Susanne, Abrahamsson, Annelie, Rodriguez, Gabriela Vazquez, Olsson, Anna-Karin, Jensen, Lasse, Cao, Yihai, Dabrosin, Charlotta

“…Novel therapeutic targets of estrogen receptor (ER)-positive breast cancers are urgently needed because current antiestrogen therapy causes severe adverse…”
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Equal Pro-inflammatory Profiles of CCLs, CXCLs, and Matrix Metalloproteinases in the Extracellular Microenvironment In Vivo in Human Dense Breast Tissue and Breast Cancer by Abrahamsson, Annelie, Rzepecka, Anna, Dabrosin, Charlotta

“…The inflammatory microenvironment affects breast cancer progression. Proteins that govern the inflammatory response are secreted into the extracellular space,…”
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Breast density and estradiol are associated with distinct different expression patterns of metabolic proteins in normal human breast tissue in vivo by Ekstrand, Jimmy, Abrahamsson, Annelie, Lundberg, Peter, Dabrosin, Charlotta

“…Breast density and exposure to sex steroids are major risk factors for breast cancer. The local microenvironment plays an essential role in progression of…”
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Tamoxifen, Flaxseed, and the Lignan Enterolactone Increase Stroma- and Cancer Cell-Derived IL-1Ra and Decrease Tumor Angiogenesis in Estrogen-Dependent Breast Cancer by LINDAHL, Gabriel, SAARINEN, Niina, ABRAHAMSSON, Annelie, DABROSIN, Charlotta

“…The proinflammatory cytokines IL-1α and IL-1β promote tumor angiogenesis that might be counteracted by the IL-1 receptor antagonist (IL-1Ra), anakinra, a…”
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Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo by Garvin, Stina, Öllinger, Karin, Dabrosin, Charlotta

“…Resveratrol, a polyphenol found in grapes and wine, is considered a potential cancer chemopreventive agent. Resveratrol has been shown to induce transcription…”
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Estradiol Promotes Breast Cancer Cell Migration via Recruitment and Activation of Neutrophils by Vazquez Rodriguez, Gabriela, Abrahamsson, Annelie, Jensen, Lasse Dahl Ejby, Dabrosin, Charlotta

“…Estradiol (E ) plays a key role in breast cancer progression. Most breast cancer recurrences express the estrogen receptor (ER), but nearly 50% of patients are…”
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Breast Density and Estradiol Are Major Determinants for Soluble TNF-TNF-R Proteins in vivo in Human Breast Tissue by Ekstrand, Jimmy, Zemmler, Maja, Abrahamsson, Annelie, Lundberg, Peter, Forsgren, Mikael, Dabrosin, Charlotta

“…High mammographic density and exposure to sex steroids are independent risk factors for breast cancer by yet unknown mechanisms. Inflammation is one hallmark…”
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Increased Extracellular Osteopontin Levels in Normal Human Breast Tissue at High Risk of Developing Cancer and Its Association With Inflammatory Biomarkers in situ by Lindahl, Gabriel, Rzepecka, Anna, Dabrosin, Charlotta

“…Mammographic breast density is a strong independent risk factor for breast cancer (BC), but the molecular mechanisms behind this risk is yet undetermined and…”
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Low-dose acetylsalicylic acid reduces local inflammation and tissue perfusion in dense breast tissue in postmenopausal women by Lundberg, Peter, Abrahamsson, Annelie, Kihlberg, Johan, Tellman, Jens, Tomkeviciene, Ieva, Karlsson, Anette, Kristoffersen Wiberg, Maria, Warntjes, Marcel, Dabrosin, Charlotta

“…One major risk factor for breast cancer is high mammographic density. It has been estimated that dense breast tissue contributes to ~ 30% of all breast cancer…”
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Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer via Upregulation of U2AF1 and RPN2 Proteins by Vazquez Rodriguez, Gabriela, Abrahamsson, Annelie, Turkina, Maria V, Dabrosin, Charlotta

“…The majority of estrogen receptor positive (ER+) breast cancer (BC) maintain the ER at metastatic sites. Despite anti-estrogen therapy, almost 30% of ER+ BC…”
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Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8 by Vazquez Rodriguez, Gabriela, Abrahamsson, Annelie, Jensen, Lasse Dahl Ejby, Dabrosin, Charlotta

“…Fat is a major tissue component in human breast cancer (BC). Whether breast adipocytes (BAd) affect early stages of BC metastasis is yet unknown. BC…”
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Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer by Leifler, Karin Söderlund, Svensson, Susanne, Abrahamsson, Annelie, Bendrik, Christina, Robertson, Jennifer, Gauldie, Jack, Olsson, Anna-Karin, Dabrosin, Charlotta

“…Matrix metalloproteinases (MMPs) have been suggested as therapeutic targets in cancer treatment, but broad-spectrum MMP inhibitors have failed in clinical…”
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Positive Correlation between Estradiol and Vascular Endothelial Growth Factor but not Fibroblast Growth Factor-2 in Normal Human Breast Tissue In vivo by DABROSIN, Charlotta

“…Purpose: Angiogenesis is crucial in tumor development and progression. Ovarian hormones regulate angiogenesis in the reproductive tract but very little is…”
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Flaxseed and Its Lignans Inhibit Estradiol-Induced Growth, Angiogenesis, and Secretion of Vascular Endothelial Growth Factor in Human Breast Cancer Xenografts In vivo by JUNGESTRÖM, Malin Bergman, THOMPSON, Lilian U, DABROSIN, Charlotta

“…Purpose: Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis, which is crucial in cancer progression. We have previously shown…”
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Estrogen‐induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo by Saarinen, Niina M., Abrahamsson, Annelie, Dabrosin, Charlotta

“…Angiogenesis is a key in cancer progression and its regulators are released both by the tumor cells and the stroma. Dietary phytoestrogens, such as the lignan…”
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In vivo measurement of tumor estradiol and vascular endothelial growth factor in breast cancer patients by Garvin, Stina, Dabrosin, Charlotta

“…Angiogenesis, crucial for tumor progression, is a process regulated in the tissue micro-environment. Vascular endothelial growth factor (VEGF) is a potent…”
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MMP-2 and MMP-9 activity is regulated by estradiol and tamoxifen in cultured human breast cancer cells by NILSSON, Ulrika W, GARVIN, Stina, DABROSIN, Charlotta

“…Sex steroids play a dominant role in breast carcinogenesis by still largely unknown mechanisms. Matrix metalloproteinases (MMPs) have been extensively studied…”
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Tamoxifen and flaxseed alter angiogenesis regulators in normal human breast tissue in vivo by Åberg, Ulrika W Nilsson, Saarinen, Niina, Abrahamsson, Annelie, Nurmi, Tarja, Engblom, Sofia, Dabrosin, Charlotta

“…The incidence of breast cancer is increasing in the Western world and there is an urgent need for studies of the mechanisms of sex steroids in order to develop…”
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Zebrafish tumour xenograft models: a prognostic approach to epithelial ovarian cancer by Lindahl, Gabriel, Fjellander, Sebastian, Selvaraj, Karthik, Vildeval, Malin, Ali, Zaheer, Almter, Rusul, Erkstam, Anna, Rodriguez, Gabriela Vazquez, Abrahamsson, Annelie, Kersley, Åsa Rydmark, Fahlgren, Anna, Kjølhede, Preben, Linder, Stig, Dabrosin, Charlotta, Jensen, Lasse

“…Epithelial ovarian cancer (EOC) is the gynaecological malignancy with highest mortality. Although adjuvant treatment with carboplatin and paclitaxel leads to…”
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