Search Results - "Dabirian, Sara"
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Process optimization for green synthesis of silver nanoparticles using Rubus discolor leaves extract and its biological activities against multi-drug resistant bacteria and cancer cells
Published in Scientific reports (19-02-2024)“…Multi-drug resistant (MDR) bacteria are considered a serious public health threat. Also, increasing rate of resistance to anticancer drugs, as well as their…”
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Phytochemical analysis, antioxidant, antibacterial, and cytotoxic activities of leaves and roots of Rubus hyrcanus Juz
Published in European food research & technology (2022)“…Rubus hyrcanus Juz. (Rosaceae), known as Caspian blackberry, is wildly distributed around the Caspian Sea. This study focused on antioxidant, cytotoxic, and…”
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Inhibitory effect of temozolomide on apoptosis induction of cinnamaldehyde in human glioblastoma multiforme T98G cell line
Published in Anatomy & cell biology (31-03-2024)“…Glioblastoma is the most common primary malignant brain tumor in adults. Temozolomide (TMZ) is an FDA-approved drug used to treat this type of cancer…”
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4
An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats
Published in Molecular biology reports (01-04-2021)“…Inflammatory bowel disease (IBD) is considered a chronic inflammatory gastrointestinal disease with treatment options which exhibit low efficacies and lead to…”
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Phytochemical analysis and antioxidant activity of eight cultivars of tea (Camellia sinensis) and rapid discrimination with FTIR spectroscopy and pattern recognition techniques
Published in Pharmaceutical Sciences (01-01-2023)“…Background: Tea (Camellia sinensis L.O. Kuntze) is one of the most commonly consumed beverages globally, with several beneficial health effects. The…”
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Application of a Deep Eutectic Solvent for the Synthesis of Novel Imidazole-Containing Quinazoline Derivatives as Potent Cytotoxic Agents
Published in Pharmaceutical Sciences (01-04-2024)“…Background: Drugs containing the 4-anilinoquinazolines scaffold play a critical role in cancer treatment by inhibiting protein kinases, especially tyrosine…”
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Synthesis, biological evaluation, and in silico study of novel coumarin-quinazoline analogs as potential Anti-Angiogenesis agents
Published in Results in Chemistry (01-10-2024)“…[Display omitted] •Novel series of coumarin-quinazoline derivatives were successfully designed and synthesized.•Compound 13f demonstrated notable inhibitory…”
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Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate
Published in PLoS neglected tropical diseases (2013)“…The toxicity of available drugs for treatment of leishmaniasis, coupled with emerging drug resistance, make it urgent to find new therapies. Antimicrobial…”
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Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line
Published in Anatomy & cell biology (31-03-2021)“…Papillary thyroid carcinoma (PTC) is one of the most common cancers of the endocrine system. Previous studies have shown that the extract of hull-less pumpkin…”
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Comparison of MTT, trypan blue, and clonogenic assay, to determine the viability in human anaplastic thyroid cancer cell line
Published in Majallah-i Danishkadah-'i Pizishki (01-04-2019)“…Background: Evaluation of cell viability is momentous in pharmacologic and oncological research. Cell viability evaluation determines cell sensitivity and…”
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Green synthesis of silver nanoparticles from Stachys byzantina K. Koch: characterization, antioxidant, antibacterial, and cytotoxic activity
Published in Particulate science and technology (17-02-2022)“…In the present study, silver nanoparticles were synthesized by aqueous extract of Stachys byzantina K. Koch and characterized by various analytical methods…”
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Inhibitory effect of temozolomide on apoptosis induction of cinnamaldehyde in human glioblastoma multiforme T98G cell line
Published in Anatomy & cell biology (30-06-2024)Get full text
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13
Inhibitory effect of temozolomide on apoptosis induction of cinnamaldehyde in human glioblastoma multiforme T98G cell line
Published in Anatomy & cell biology (01-06-2024)“…Glioblastoma is the most common primary malignant brain tumor in adults. Temozolomide (TMZ) is an FDA-approved drug used to treat this type of cancer…”
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Novel agonists of benzodiazepine receptors: Design, synthesis, binding assay and pharmacological evaluation of 1,2,4-triazolo[1,5-a]pyrimidinone and 3-amino-1,2,4-triazole derivatives
Published in Bioorganic & medicinal chemistry (01-02-2015)“…Based on SAR of benzodiazepine receptor agonists, novel scaffold are introduced as hypnotic and anticonvulsant agents without any impairing effect on memory…”
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15
Effects of melatonin on the toxicity and proliferation of human anaplastic thyroid cancer cell line
Published in Acta histochemica (01-04-2021)“…•Melatonin cytotoxic effects induced late apoptosis in ATC cells Thyroid carcinoma is the most common endocrine malignancy and anaplastic thyroid carcinoma…”
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Novel 4-Anilinoquinazoline Derivatives as Potent Anticancer Agents: Design, Synthesis, Cytotoxic Activity, and Docking Study
Published in Critical studies in media communication (01-01-2021)“…The simultaneous inhibition of EGFR and VEGFR-2 is a promising method in cancer treatment. In the present work, several 4-anilinoquinazoline derivatives…”
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Association of CYP2D64 Polymorphism With Response to Atorvastatin in Patients With High Low-Density Lipoprotein Level in Northern Iran, Guilan Provice
Published in Majallah-i Dānishgāh-i ʻUlūm-i Pizishkī-i Gīlān (01-04-2023)“…Background: People who take statins respond differently to them due to genetic differences. One of the most significant enzymes involved in drug metabolism is…”
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Cytotoxicity Effect of Hull-Less Seed Pumpkin Extract on Human Papillary Thyroid Cancer Cell Line
Published in Anatomical sciences journal (01-08-2020)“…Introduction: Thyroid cancer is the most prevalent endocrine malignancy tumor, and its incidence is increasing. Chemotherapy drugs like Paclitaxel (PTX) are a…”
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Human Neutrophil Peptide-1 (HNP-1): A New AntiLeishmanial Drug Candidate
Published in PLoS neglected tropical diseases (01-10-2013)Get full text
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Optimum conditions of radioligand receptor binding assay of ligands of benzodiazepine receptors
Published in Iranian journal of pharmaceutical research : IJPR (2014)“…To obtain drugs which are more selective at benzodiazepine (BZD) receptors, design and synthesis of functionally selective ligands for BZD receptors is the…”
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