Search Results - "DaRocha, Wanderson Duarte"

Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion by Demeu, Lara Maria Kalempa, Soares, Rodrigo Jahn, Miranda, Juliana Severo, Pacheco-Lugo, Lisandro A, Oliveira, Kelin Gonçalves, Cortez Plaza, Cristian Andrés, Billiald, Philippe, Ferreira de Moura, Juliana, Yoshida, Nobuko, Alvarenga, Larissa Magalhães, DaRocha, Wanderson Duarte

“…Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs…”
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An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway by Serpeloni, Mariana, Moraes, Carolina Borsoi, Muniz, João Renato Carvalho, Motta, Maria Cristina Machado, Ramos, Augusto Savio Peixoto, Kessler, Rafael Luis, Inoue, Alexandre Haruo, daRocha, Wanderson Duarte, Yamada-Ogatta, Sueli Fumie, Fragoso, Stenio Perdigão, Goldenberg, Samuel, Freitas-Junior, Lucio H, Avila, Andréa Rodrigues

“…In eukaryotic cells, different RNA species are exported from the nucleus via specialized pathways. The mRNA export machinery is highly integrated with mRNA…”
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Lipidomic Analysis Reveals Branched-Chain and Cyclic Fatty Acids from Angomonas deanei Grown under Different Nutritional and Physiological Conditions by Santana-Filho, Arquimedes Paixão, Pereira, Aramís José, Laibida, Letícia Adejani, Souza-Melo, Normanda, DaRocha, Wanderson Duarte, Sassaki, Guilherme Lanzi

“…belongs to family, a family of parasites that only infect insects. It hosts a bacterial endosymbiont in a mutualistic relationship, constituting an excellent…”
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Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes by de Paiva, Rita Marcia Cardoso, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana Monte Cassiano, Souza Melo, Normanda, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza M R

“…Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania…”
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Effective gene delivery to Trypanosoma cruzi epimastigotes through nucleofection by Pacheco-Lugo, Lisandro, Díaz-Olmos, Yirys, Sáenz-García, José, Probst, Christian Macagnan, DaRocha, Wanderson Duarte

“…New opportunities have raised to study the gene function approaches of Trypanosoma cruzi after its genome sequencing in 2005. Functional genomic approaches in…”
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Trypanosoma cruzi: role of δ-amastin on extracellular amastigote cell invasion and differentiation by Cruz, Mário C, Souza-Melo, Normanda, da Silva, Claudio Vieira, Darocha, Wanderson Duarte, Bahia, Diana, Araújo, Patrícia R, Teixeira, Santuza R, Mortara, Renato A

“…Trypanosoma cruzi is a protozoan parasite that comprises different phylogenetic groups and is the causative agent of Chagas' disease. Different T. cruzi…”
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Correction: Trypanosoma cruzi: Role of δ-Amastin on Extracellular Amastigote Cell Invasion and Differentiation by Cruz, Mário C., Souza-Melo, Normanda, da Silva, Claudio Vieira, DaRocha, Wanderson Duarte, Bahia, Diana, Araújo, Patrícia R., Teixeira, Santuza R., Mortara, Renato A.

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Distinct genomic organization, mRNA expression and cellular localization of members of two amastin sub-families present in Trypanosoma cruzi by Kangussu-Marcolino, Monica Mendes, de Paiva, Rita Márcia Cardoso, Araújo, Patrícia Rosa, de Mendonça-Neto, Rondon Pessoa, Lemos, Laiane, Bartholomeu, Daniella Castanheira, Mortara, Renato A, daRocha, Wanderson Duarte, Teixeira, Santuza Maria Ribeiro

“…Amastins are surface glycoproteins (approximately 180 residues long) initially described in Trypanosoma cruzi as particularly abundant during the amastigote…”
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Assessment of two CRISPR-Cas9 genome editing protocols for rapid generation of Trypanosoma cruzi gene knockout mutants by Burle-Caldas, Gabriela Assis, Soares-Simões, Melissa, Lemos-Pechnicki, Laiane, DaRocha, Wanderson Duarte, Teixeira, Santuza M.R.

“…[Display omitted] •We obtained fast generation of Trypanosoma cruzi GP72 knockout using Cas9 and in vitro transcribed single guide RNA.•Trypanosoma cruzi…”
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Trypanosoma cruzi Vps34 colocalizes with Beclin1 and plays a role in parasite invasion of the host cell by modulating the expression of a sub-group of trans-sialidases by Nájera, Carlos Alcides, Soares-Silva, Mercedes, Maeda, Fernando Y., DaRocha, Wanderson Duarte, Meneghelli, Isabela, Mendes, Ana Clara, Batista, Marina Ferreira, Silva, Claudio Vieira, da Silveira, José Franco, Orikaza, Cristina M., Yoshida, Nobuko, Silva, Viviane Grazielle, Teixeira, Santuza Maria Ribeiro, Bartholomeu, Daniella Castanheira, Bahia, Diana

“…Trypanosoma cruzi, the etiological agent of Chagas' disease, can infect both phagocytic and non-phagocytic cells. T. cruzi gp82 and gp90 are cell surface…”
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Expanding the tool box for genetic manipulation of Trypanosoma cruzi by Burle-Caldas, Gabriela de Assis, Grazielle-Silva, Viviane, Laibida, Letícia Adejani, DaRocha, Wanderson Duarte, Teixeira, Santuza Maria Ribeiro

“…Molecular tools and protocols available to perform genetic manipulation of the T. cruzi genome now include strategies of gene editing. [Display omitted] •More…”
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Differential ability to resist to complement lysis and invade host cells mediated by MBL in R4 and 860 strains of Trypanosoma cruzi by Evans-Osses, Ingrid, Mojoli, Andres, Beltrame, Marcia Holsbach, da Costa, Denise Endo, DaRocha, Wanderson Duarte, Velavan, Thirumalaisamy P., de Messias-Reason, Iara, Ramirez, Marcel Ivan

“…•MBL has a central role in the activation of Complement Lectin Pathway.•Trypanosoma cruzi displays strains resistant or sensitive to complement Lysis.•The…”
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Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli by Stoco, Patrícia Hermes, Wagner, Glauber, Talavera-Lopez, Carlos, Gerber, Alexandra, Zaha, Arnaldo, Thompson, Claudia Elizabeth, Bartholomeu, Daniella Castanheira, Lückemeyer, Débora Denardin, Bahia, Diana, Loreto, Elgion, Prestes, Elisa Beatriz, Lima, Fábio Mitsuo, Rodrigues-Luiz, Gabriela, Vallejo, Gustavo Adolfo, Filho, José Franco da Silveira, Schenkman, Sérgio, Monteiro, Karina Mariante, Tyler, Kevin Morris, de Almeida, Luiz Gonzaga Paula, Ortiz, Mauro Freitas, Chiurillo, Miguel Angel, de Moraes, Milene Höehr, Cunha, Oberdan de Lima, Mendonça-Neto, Rondon, Silva, Rosane, Teixeira, Santuza Maria Ribeiro, Murta, Silvane Maria Fonseca, Sincero, Thais Cristine Marques, Mendes, Tiago Antonio de Oliveira, Urmenyi, Turán Peter, Silva, Viviane Grazielle, DaRocha, Wanderson Duarte, Andersson, Björn, Romanha, Alvaro José, Steindel, Mário, de Vasconcelos, Ana Tereza Ribeiro, Grisard, Edmundo Carlos

“…Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans and other wild and domestic mammals across Central and South America. It does not…”
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Editing the Trypanosoma cruzi genome with zinc finger nucleases by Burle-Caldas, Gabriela Assis, Grazielle-Silva, Viviane, Soares-Simões, Melissa, Schumann Burkard, Gabriela, Roditi, Isabel, DaRocha, Wanderson Duarte, Teixeira, Santuza M.

“…[Display omitted] •T. cruzi constitutively expressing ZFNs employs endogenous sequences to repair DSBs.•Expression of synthetic ZFNs in T. cruzi does not…”
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Effective gene delivery to Trypanosoma cruzi epimastigotes through n ucleofection by Pacheco-Lugo, Lisandro, Díaz-Olmos, Yirys, Sáenz-García, José, Probst, Christian Macagnan, DaRocha, Wanderson Duarte

“…Abstract New opportunities have raised to study the gene function approaches of Trypanosoma cruzi after its genome sequencing in 2005. Functional genomic…”
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Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes: e1005296 by Paiva, Marcia Cardosode, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana MonteCassiano, Melo, Normanda Souza, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza MR

“…Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania…”
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Trypanosoma cruzi: Role of [delta]-Amastin on Extracellular Amastigote Cell Invasion and Differentiation by Cruz, Mário C, Souza-Melo, Normanda, da Silva, Claudio Vieira, DaRocha, Wanderson Duarte, Bahia, Diana, Araújo, Patrícia R, Teixeira, Santuza R, Mortara, Renato A

“…Trypanosoma cruzi is a protozoan parasite that comprises different phylogenetic groups and is the causative agent of Chagas' disease. Different T. cruzi…”
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Genome of the Avirulent Human-Infective Trypanosome-- Trypanosoma rangeli: e3176 by Stoco, Patrícia Hermes, Wagner, Glauber, Talavera-Lopez, Carlos, Gerber, Alexandra, Zaha, Arnaldo, Thompson, Claudia Elizabeth, Bartholomeu, Daniella Castanheira, Lückemeyer, Débora Denardin, Bahia, Diana, Loreto, Elgion, Prestes, Elisa Beatriz, Lima, Fábio Mitsuo, Rodrigues-Luiz, Gabriela, Vallejo, Gustavo Adolfo, Filho, Franco daSilveira, Schenkman, Sérgio, Monteiro, Karina Mariante, Tyler, Kevin Morris, Almeida, Gonzaga Paulade, Ortiz, Mauro Freitas, Chiurillo, Miguel Angel, Moraes, Milene Höehrde, Cunha, Oberdan deLima, Mendonça-Neto, Rondon, Silva, Rosane, Teixeira, Santuza MariaRibeiro, Murta, Silvane MariaFonseca, Sincero, Thais CristineMarques, Mendes, Antonio deOliveira, Urmenyi, Turán Peter, Silva, Viviane Grazielle, DaRocha, Wanderson Duarte, Andersson, Björn, Romanha, Álvaro José, Steindel, Mário, Vasconcelos, Tereza Ribeirode, Grisard, Edmundo Carlos

“…Background Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans and other wild and domestic mammals across Central and South America. It…”
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Biochemical studies with DNA polymerase β and DNA polymerase β-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance by Lopes, Débora de Oliveira, Schamber-Reis, Bruno Luiz Fonseca, Regis-da-Silva, Carlos Gustavo, Rajão, Matheus Andrade, DaRocha, Wanderson Duarte, Macedo, Andréa Mara, Franco, Glória Regina, Nardelli, Sheila Cristina, Schenkman, Sérgio, Hoffmann, Jean-Sébastien, Cazaux, Christophe, Pena, Sérgio Danilo Junho, Teixeira, Santuza Maria Ribeiro, Machado, Carlos Renato

“…Mammalian DNA polymerase β is a nuclear enzyme involved in the base excision and single-stranded DNA break repair pathways. In trypanosomatids, this protein…”
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Characterization of the Trypanosoma cruzi Rad51 gene and its role in recombination events associated with the parasite resistance to ionizing radiation by Regis-da-Silva, Carlos Gustavo, Freitas, Jorge Marcelo, Passos-Silva, Danielle Gomes, Furtado, Carolina, Augusto-Pinto, Luiz, Pereira, Márcio Tadeu, DaRocha, Wanderson Duarte, Franco, Glória Regina, Macedo, Andréa Mara, Hoffmann, Jean-Sebastien, Cazaux, Christophe, Pena, Sérgio Danilo Junho, Teixeira, Santuza Maria Ribeiro, Machado, Carlos Renato

“…The Rad51 gene encodes a highly conserved enzyme involved in DNA double-strand break (DSB) repair and recombination processes. We cloned and characterized the…”
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