Search Results - "DaGama Gomes, Erica M."

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species by Zong, Hongliang, Gozman, Alexander, Caldas-Lopes, Eloisi, Taldone, Tony, Sturgill, Eric, Brennan, Sarah, Ochiana, Stefan O., Gomes-DaGama, Erica M., Sen, Siddhartha, Rodina, Anna, Koren, John, Becker, Michael W., Rudin, Charles M., Melnick, Ari, Levine, Ross L., Roboz, Gail J., Nimer, Stephen D., Chiosis, Gabriela, Guzman, Monica L.

“…Acute myeloid leukemia (AML) is a heterogeneous and fatal disease with an urgent need for improved therapeutic regimens given that most patients die from…”
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Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer by Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D, Koren, John, Yan, Pengrong, DaGama Gomes, Erica M, Yang, Chenghua, Patel, Maulik R, Shrestha, Liza, Ochiana, Stefan O, Santarossa, Cristina, Maharaj, Ronnie, Gozman, Alexander, Cox, Marc B, Erdjument-Bromage, Hediye, Hendrickson, Ronald C, Cerchietti, Leandro, Melnick, Ari, Guzman, Monica L, Chiosis, Gabriela

“…Heat shock protein 70 (Hsp70) is a family of proteins with key roles in regulating malignancy. Cancer cells rely on Hsp70 to inhibit apoptosis, regulate…”
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Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 by Moulick, Kamalika, Ahn, James H, Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Gomes DaGama, Erica M, Caldas-Lopes, Eloisi, Beebe, Kristin, Perna, Fabiana, Hatzi, Katerina, Vu, Ly P, Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven S, Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason S, Larson, Steven M, Levine, Ross, Erdjument-Bromage, Hediye, Guzman, Monica L, Nimer, Stephen D, Melnick, Ari, Neckers, Len, Chiosis, Gabriela

“…The inhibitor PU-H71 preferentially targets tumor-enriched Hsp90 complexes. Affinity purification using PU-H71 reveals cancer-specific protein networks in…”
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Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions by Jhaveri, Komal, Ochiana, Stefan O, Dunphy, Mark Ps, Gerecitano, John F, Corben, Adriana D, Peter, Radu I, Janjigian, Yelena Y, Gomes-DaGama, Erica M, Koren, 3rd, John, Modi, Shanu, Chiosis, Gabriela

“…Heat shock protein 90 (HSP90) serves as a critical facilitator for oncogene addiction. There has been augmenting enthusiasm in pursuing HSP90 as an anticancer…”
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Synthesis and evaluation of cell-permeable biotinylated PU-H71 derivatives as tumor Hsp90 probes by Taldone, Tony, Rodina, Anna, DaGama Gomes, Erica M, Riolo, Matthew, Patel, Hardik J, Alonso-Sabadell, Raul, Zatorska, Danuta, Patel, Maulik R, Kishinevsky, Sarah, Chiosis, Gabriela

“…The attachment of biotin to a small molecule provides a powerful tool in biology. Here, we present a systematic approach to identify biotinylated analogues of…”
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Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy by Taldone, Tony, Gomes-DaGama, Erica M., Zong, Hongliang, Sen, Siddhartha, Alpaugh, Mary L., Zatorska, Danuta, Alonso-Sabadell, Raul, Guzman, Monica L., Chiosis, Gabriela

“…Fluorescent ligands for the heat shock protein 90 (Hsp90) were synthesized containing either fluorescein isothiocyanate (FITC), 4-nitrobenzo[1,2,5]oxadiazole…”
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Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET by Janjigian, Yelena Y, Viola-Villegas, Nerissa, Holland, Jason P, Divilov, Vadim, Carlin, Sean D, Gomes-DaGama, Erica M, Chiosis, Gabriela, Carbonetti, Gregory, de Stanchina, Elisa, Lewis, Jason S

“…We evaluated the ability of the PET imaging agent (89)Zr-trastuzumab to delineate HER2-positive gastric cancer and to monitor the pharmacodynamic effects of…”
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Monitoring Afatinib Treatment in HER2-Positive Gastric Cancer with 18 F-FDG and 89 Zr-Trastuzumab PET by Janjigian, Yelena Y., Viola-Villegas, Nerissa, Holland, Jason P., Divilov, Vadim, Carlin, Sean D., Gomes-DaGama, Erica M., Chiosis, Gabriela, Carbonetti, Gregory, de Stanchina, Elisa, Lewis, Jason S.

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Monitoring Afatinib Treatment in HER2-Positive Gastric Cancer with ^sup 18^F-FDG and ^sup 89^Zr-Trastuzumab PET by Janjigian, Yelena Y, Viola-Villegas, Nerissa, Holland, Jason P, Divilov, Vadim, Carlin, Sean D, Gomes-DaGama, Erica M, Chiosis, Gabriela, Carbonetti, Gregory, de Stanchina, Elisa, Lewis, Jason S

“…We evaluated the ability of the PET imaging agent ...-trastuzumab to delineate HER2-positive gastric cancer and to monitor the pharmacodynamic effects of the…”
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Abstract 5444: Development of a noninvasive assay to determine drug concentration in tumor during hsp90 inhibitor therapy by Taldone, Tony, Pillarsetty, Nagavarakishore, Dunphy, Mark PS, Gerecitano, John F., Caldas-Lopes, Eloisi, Beattie, Brad, Peter, Radu I., Kang, Yanlong, Rodina, Anna, Yan, Pengrong, DaGama Gomes, Erica M., Bolaender, Alexander, Pressl, Christina, Punzalan, Blesida, Ku, Anson, Ku, Thomas, Shah, Smit, Uddin, Mohammad, Chen, Mei H., Santos, Elmer, Koziorowski, Jacek, Corben, Adriana, Modi, Shanu, Jhaveri, Komal, Lin, Oscar, Vakiani, Efsevia, Janjigian, Yelena, Zanzonico, Pat, Hudis, Clifford, Larson, Steven M., Lewis, Jason S., Chiosis, Gabriela

“…As molecularly targeted agents assume a more prominent role in anticancer therapy there is a growing need to determine in a noninvasive manner whether the…”
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Abstract 1263: Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 by Gomes-DaGama, Erica M., Moulick, Kamalika, Ahn, James H., Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Lopes-Vazquez, Maria E. Caldas, Beebe, Kristin, Perna, Fabiana, Katerina, Chatzi, Vu, Ly P., Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven S., Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason S., Larson, Steven M., Ross, Levine, Erdjument-Bromage, Hediye, Guzman, Monica L., Nimer, Stephen D., Melnick, Ari M., Neckers, Len, Chiosis, Gabriela

“…Most cancers are characterized by multiple molecular alterations, but identification of the key proteins involved in these signaling pathways is currently…”
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