Search Results - "Da Silva Junior, Pedro Ismael"
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Patagonin-CRISP: Antimicrobial Activity and Source of Antimicrobial Molecules in Duvernoy's Gland Secretion ( Philodryas patagoniensis Snake)
Published in Frontiers in pharmacology (02-02-2021)“…Snake venom contains a variety of toxins with a range of biological activity, among these toxins cysteine-rich secreted proteins (CRISPs) can be found. The…”
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Garlic: An Alternative Treatment for Group B Streptococcus
Published in Microbiology spectrum (22-12-2021)“…Prenatal screening in pregnant women between 35 and 37 weeks of gestation and intrapartum antibiotic prophylaxis has successfully reduced the incidence of…”
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3
Acylpolyamine Mygalin as a TLR4 Antagonist Based on Molecular Docking and In Vitro Analyses
Published in Biomolecules (Basel, Switzerland) (01-12-2020)“…Toll-like receptors (TLRs) are transmembrane proteins that are key regulators of innate and adaptive immune responses, particularly TLR4, and they have been…”
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Two new Dolichothele Mello-Leitão, 1923 species from Brazil and Bolivia (Araneae, Theraphosidae)
Published in ZooKeys (21-12-2017)“…Two new species of Mello-Leitão, 1923 are described from Brazil and Bolivia, from Distrito Federal and the state of Goiás, Brazil, and from the state of…”
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Two Tachykinin-Related Peptides with Antimicrobial Activity Isolated from Triatoma infestans Hemolymph
Published in Microbiology insights (01-01-2020)“…Antimicrobial peptides and proteins (AMPs) are molecules that can interact with microbial cells and lead to membrane disruption or intracellular molecule…”
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Presynaptic Activity of an Isolated Fraction from Rhinella schneideri Poison
Published in Advanced pharmaceutical bulletin (01-08-2018)“…In chick biventer cervicis in vitro nerve-muscle preparation, the poison leads to neuromuscular blockade by inhibiting acetylcholine release, without…”
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Insights into Antimicrobial Peptides from Limacus flavus Mucus
Published in Current microbiology (01-08-2021)“…Antimicrobial peptides have been a major research subject since the rise of antimicrobial resistance as a major public health problem. These molecules are…”
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Secretion of the arthrodial membrane gland of a harvester (Arachnida: Opiliones): Antimicrobial activity
Published in Journal of invertebrate pathology (01-09-2024)“…•“Molecules with antimicrobial activity in the secretion of the arthrodial membrane glande of a harvester (Arachnida, Opiliones)” (Short communications) −…”
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Mygalin, an Acanthoscurria gomesiana spider-derived synthetic, modulates haloperidol-induced cataleptic state in mice
Published in Neuroscience letters (18-01-2024)“…Haloperidol (HAL) is an antipsychotic used in the treatment of schizophrenia. However, adverse effects are observed in the extrapyramidal tracts due to its…”
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In Silico and In Vitro Approach for Evaluation of the Anti-Inflammatory and Antioxidant Potential of Mygalin
Published in International journal of molecular sciences (01-12-2023)“…There is a great interest in describing new molecules to be used as therapeutic targets in various diseases, particularly those that play a role in…”
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Presence of a neprilysin on Avicularia juruensis (Mygalomorphae: Theraphosidae) venom
Published in Toxin reviews (03-04-2022)“…Spiders are the most successful and diversified group of venomous animals. Currently, there are more than 49,000 species distributed almost all over the world…”
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Serrulin: A Glycine-Rich Bioactive Peptide from the Hemolymph of the Yellow Tityus serrulatus Scorpion
Published in Toxins (06-09-2019)“…Antimicrobial peptides (AMPs) are small molecules, which have a potential use as antibiotic or pharmacological tools. In chelicerate organisms, such as…”
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Chemosensory discrimination of male age by female Psammodromus algirus lizards based on femoral secretions and feces
Published in Ethology (01-11-2019)“…Chemical communication plays an essential role in several social and reproductive behaviors of many animals. In lizards, the main sources of semiochemicals are…”
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Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
Published in PloS one (20-12-2016)“…In contrast to vertebrate immune systems, invertebrates lack an adaptive response and rely solely on innate immunity in which antimicrobial peptides (AMPs)…”
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Antimicrobial activity of leucine‐substituted decoralin analogs with lower hemolytic activity
Published in Journal of peptide science (01-11-2017)“…Linear cationic α‐helical antimicrobial peptides are promising chemotherapeutics. Most of them act by different mechanisms, making it difficult to…”
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Molecular hybridization strategy for tuning bioactive peptide function
Published in Communications biology (19-10-2023)“…The physicochemical and structural properties of antimicrobial peptides (AMPs) determine their mechanism of action and biological function. However, the…”
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Protein Components of the Arthrodial Membrane Gland in a Neotropical Harvestman (Arachnida, Opiliones)
Published in ACS omega (28-12-2021)“…The content of arthrodial membrane glands in arthropods has seldom been studied. Here, we have analyzed the proteins of the arthrodial membrane gland of the…”
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Hemoglobin Reassembly of Antimicrobial Fragments from the Midgut of Triatoma infestans
Published in Biomolecules (Basel, Switzerland) (10-02-2020)“…Hemoglobin is one of the most important molecules of the human body. Beyond its physiological activity, hemoglobins are able to inhibit the growth of several…”
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Mating behavior of Sickius longibulbi (Araneae, Theraphosidae, Ischnocolinae), a spider that lacks spermathecae
Published in The Journal of arachnology (01-08-2008)“…We describe the mating behavior in the spermatheca-lacking theraphosid species Sickius longibulbiSoares & Camargo 1948. The behavior in captivity of nine pairs…”
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Acanthoscurria gomesiana spider‐derived synthetic mygalin in the dorsal raphe nucleus modulates acute and chronic pain
Published in Journal of biochemical and molecular toxicology (01-10-2021)“…Mygalin, a diacylspermidine that is naturally found in the hemolymph of the spider Acanthoscurria gomesiana, is of interest for development as a potential…”
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