Search Results - "Da Silva, Thaís Costa"
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Antiparasitic activity of natural and semi-synthetic tirucallane triterpenoids from Schinus terebinthifolius (Anacardiaceae): structure/activity relationships
Published in Molecules (Basel, Switzerland) (05-05-2014)“…Leishmaniasis and Chagas are diseases caused by parasitic protozoans that affect the poorest population in the World, causing a high mortality and morbidity…”
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Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)
Published in The journal of venomous animals and toxins including tropical diseases (2019)“…BACKGROUNDVisceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong…”
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Antiinflammatory activity of natural triterpenes—An overview from 2006 to 2021
Published in Phytotherapy research (01-04-2022)“…Terpenes are one of the most abundant classes of secondary metabolites produced by plants and can be divided based on the number of isoprene units (C5) in…”
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Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis
Published in Bioorganic & medicinal chemistry letters (15-06-2019)“…[Display omitted] Chagas disease represents one of several neglected diseases with a reduced number of chemotherapeutical drugs including the highly toxic…”
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Evolution of cytokine profile during the treatment of cerebral toxoplasmosis in HIV-infected patients
Published in Journal of immunological methods (01-11-2015)“…This study was to follow IFN-γ, TNF-α and IL-10 modulation of peripheral blood mononuclear cells (PBMC) from HIV/cerebral toxoplasmosis patients (CT) during…”
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Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis
Published in Frontiers in cellular and infection microbiology (29-10-2019)“…Liposomes containing phosphatidylserine (PS) has been used for the delivery of drugs into the intramacrophage milieu. (L.) parasites live inside macrophages…”
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Cross-Sectional Serological Survey of Human Fascioliasis in Canutama Municipality in Western Amazon, Brazil
Published in Journal of parasitology research (2018)“…Background. Fascioliasis is an important parasitic disease. In the northern region of Brazil, a human parasite infection has been reported through a…”
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Booktubers: Elogio da Materialidade e do Compartilhamento
Published in Eco-Pós (Online) (24-12-2020)“…Booktubers são leitores majoritariamente jovens que se dedicam a fazer considerações sobre exemplares literários em canais do YouTube. Por meio da análise de…”
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Efficacy of sertraline against Trypanosoma cruzi : an in vitro and in silico study
Published in The journal of venomous animals and toxins including tropical diseases (30-10-2018)“…Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. In this work, we studied the…”
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Longitudinal patterns of comorbidity between anxiety, depression and binge eating symptoms among patients with obesity: A path analysis
Published in Journal of affective disorders (15-04-2022)“…•Path modeling investigated longitudinal relationships between anxiety, depression, and binge eating symptoms among patients with obesity.•The factor time…”
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Ent-kaurane diterpenes isolated from n-hexane extract of Baccharis sphenophylla by bioactivity-guided fractionation target the acidocalcisomes in Trypanosoma cruzi
Published in Phytomedicine (Stuttgart) (01-12-2021)“…In the present work the bioactivity-guided fractionation of n-hexane extract from aerial parts of Baccharis sphenophylla (Asteraceae) against trypomastigote…”
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Caracterização da condição ambiental de lixão desativado através de indicadores de qualidade do solo
Published in Revista em agronegócio e meio ambiente (30-09-2023)“…O processo de desativação de lixões leva ao surgimento de áreas degradadas que apresentam inúmeros desafios para sua recuperação, principalmente no que diz…”
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Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria
Published in Phytomedicine (Stuttgart) (15-02-2019)“…From a previous screening of Brazilian biodiversity for antitrypanosomal activity, the n-hexane extract from twigs of Nectandra oppositifolia (Lauraceae)…”
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Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula
Published in Journal of natural products (Washington, D.C.) (22-05-2015)“…HPLC-UV-ELSD-MS-guided fractionation of the anti-parasitic extract obtained from the marine sponge Monanchora arbuscula, collected off the southeastern coast…”
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Acetylenic fatty acids from Porcelia macrocarpa (Annonaceae) against trypomastigotes of Trypanosoma cruzi: Effect of octadec-9-ynoic acid in plasma membrane electric potential
Published in Bioorganic chemistry (01-08-2018)“…[Display omitted] •Acetylene fatty acids 1–4 were isolated from flowers of Porcelia macrocarpa.•Compounds 1–3 displayed activity against T. cruzi and reduced…”
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Anti-Toxoplasma gondii antibodies in pregnant women and their newborn infants in the region of São José do Rio Preto, São Paulo, Brazil
Published in São Paulo medical journal (2011)“…Toxoplasmosis transmission during pregnancy can cause severe sequelae in fetuses and newborns. Maternal antibodies may be indicators of risk or immunity. The…”
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Histamine H1-receptor antagonists against Leishmania (L.) infantum: an in vitro and in vivo evaluation using phosphatidylserine-liposomes
Published in Acta tropica (01-09-2014)“…•Leishmania promastigotes were susceptible to seven H1-antagonists.•Cinnarizine was effective against the amastigotes, with an IC50 value of…”
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Immunomodulatory and Antileishmanial Activity of Phenylpropanoid Dimers Isolated from Nectandra leucantha
Published in Journal of natural products (Washington, D.C.) (24-04-2015)“…Three phenylpropanoid dimers (1–3) including two new metabolites were isolated from the extract of the twigs of Nectandra leucantha using antileishmanial…”
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Toxoplasma gondii antigens: Recovery analysis of tachyzoites cultivated in Vero cell maintained in serum free medium
Published in Experimental parasitology (01-04-2012)“…[Display omitted] ► This study showed the capacity of Toxoplasma gondii grown in Vero cell cultures in a medium serum-free. ► After many passages tachyzoites…”
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Propostas (in)convenientes: transpassando a opacidade do discurso sobre a educação financeira na escola
Published in REDIS (Online) (2023)“…This paper seeks to present an interpretative gesture on the intersections and direc-tions of private discourse, conveyed by Cooperative Credit System…”
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