Search Results - "Da Silva, Andrew M"

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer by Conway, James R.W., Warren, Sean C., Herrmann, David, Murphy, Kendelle J., Cazet, Aurélie S., Vennin, Claire, Shearer, Robert F., Killen, Monica J., Magenau, Astrid, Mélénec, Pauline, Pinese, Mark, Nobis, Max, Zaratzian, Anaiis, Boulghourjian, Alice, Da Silva, Andrew M., del Monte-Nieto, Gonzalo, Adam, Arne S.A., Harvey, Richard P., Haigh, Jody J., Wang, Yingxiao, Croucher, David R., Sansom, Owen J., Pajic, Marina, Caldon, C. Elizabeth, Morton, Jennifer P., Timpson, Paul

“…Application of advanced intravital imaging facilitates dynamic monitoring of pathway activity upon therapeutic inhibition. Here, we assess resistance to…”
Get full text

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology by Conway, James R. W., Vennin, Claire, Cazet, Aurélie S., Herrmann, David, Murphy, Kendelle J., Warren, Sean C., Wullkopf, Lena, Boulghourjian, Alice, Zaratzian, Anaiis, Da Silva, Andrew M., Pajic, Marina, Morton, Jennifer P., Cox, Thomas R., Timpson, Paul

“…Organotypic co-cultures bridge the gap between standard two-dimensional culture and mouse models. Such assays increase the fidelity of pre-clinical studies, to…”
Get full text

The Mini‐Organo: A rapid high‐throughput 3D coculture organotypic assay for oncology screening and drug development by Chitty, Jessica L., Skhinas, Joanna N., Filipe, Elysse C., Wang, Shan, Cupello, Carmen Rodriguez, Grant, Rhiannon D., Yam, Michelle, Papanicolaou, Michael, Major, Gretel, Zaratzian, Anaiis, Da Silva, Andrew M., Tayao, Michael, Vennin, Claire, Timpson, Paul, Madsen, Chris D., Cox, Thomas R.

“…Background The use of in vitro cell cultures is a powerful tool for obtaining key insights into the behaviour and response of cells to interventions in normal…”
Get full text

Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism by Filipe, Elysse C., Velayuthar, Sipiththa, Philp, Ashleigh, Nobis, Max, Latham, Sharissa L., Parker, Amelia L., Murphy, Kendelle J., Wyllie, Kaitlin, Major, Gretel S., Contreras, Osvaldo, Mok, Ellie T. Y., Enriquez, Ronaldo F., McGowan, Suzanne, Feher, Kristen, Quek, Lake‐Ee, Hancock, Sarah E., Yam, Michelle, Tran, Emmi, Setargew, Yordanos F. I., Skhinas, Joanna N., Chitty, Jessica L., Phimmachanh, Monica, Han, Jeremy Z. R., Cadell, Antonia L., Papanicolaou, Michael, Mahmodi, Hadi, Kiedik, Beata, Junankar, Simon, Ross, Samuel E., Lam, Natasha, Coulson, Rhiannon, Yang, Jessica, Zaratzian, Anaiis, Da Silva, Andrew M., Tayao, Michael, Chin, Ian L., Cazet, Aurélie, Kansara, Maya, Segara, Davendra, Parker, Andrew, Hoy, Andrew J., Harvey, Richard P., Bogdanovic, Ozren, Timpson, Paul, Croucher, David R., Lim, Elgene, Swarbrick, Alexander, Holst, Jeff, Turner, Nigel, Choi, Yu Suk, Kabakova, Irina V., Philp, Andrew, Cox, Thomas R.

“…In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary…”
Get full text