Search Results - "Da Ros, Silvia"
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Validation of epigenetic mechanisms regulating gene expression in canine B-cell lymphoma: An in vitro and in vivo approach
Published in PloS one (11-12-2018)“…Despite canine B-cell Lymphoma (BCL) representing the most common haematological tumour, epigenetic events driving development and progression are scarcely…”
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DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene
Published in PloS one (25-03-2019)“…The regulation of cytochrome P450 3A (CYP3A) enzymes is established in humans, but molecular mechanisms of its basal and xenobiotic-mediated regulation in…”
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3
G-Quadruplex Modulation of SP1 Functional Binding Sites at the KIT Proximal Promoter
Published in International journal of molecular sciences (30-12-2020)“…The regulation of conformational arrangements of gene promoters is a physiological mechanism that has been associated with the fine control of gene expression…”
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4
Atrial Fibrillation and Right Bundle Branch Block Complicating Coil Embolization of a Huge Pulmonary Arterio-Venous Malformation
Published in Internal Medicine (01-01-2011)“…Coil embolization is a safe therapy for pulmonary arterio-venous malformations (PAVMs). We report the case of a 72-year-old woman affected by hereditary…”
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5
Hypermethylation-Mediated Silencing of CIDEA , MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies
Published in International journal of molecular sciences (05-04-2022)“…Gene expression is controlled by epigenetic deregulation, a hallmark of cancer. The DNA methylome of canine diffuse large B-cell lymphoma (cDLBCL), the most…”
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DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma
Published in Scientific reports (14-09-2017)“…Epigenetic deregulation is a hallmark of cancer characterized by frequent acquisition of new DNA methylation in CpG islands. To gain insight into the…”
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Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models
Published in Oncotarget (19-04-2016)“…Stabilization of G-quadruplex (G4) structures in promoters is a novel promising strategy to regulate gene expression at transcriptional and translational…”
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Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?
Published in PloS one (01-08-2014)“…Downregulation of gene expression by induction of non-canonical DNA structures at promotorial level is a novel attractive anticancer strategy. In human, two…”
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Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents
Published in Bioorganic & medicinal chemistry (01-05-2017)“…[Display omitted] •Tetra- and pentacyclic indenocinnoline derivatives had good DNA binding properties.•Several tetra- and pentacyclic indenocinnoline…”
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In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c‑myc/c-Kit G‑quadruplexes
Published in ACS medicinal chemistry letters (09-08-2018)“…In the last years, it has been shown that the DNA secondary structure known as G-quadruplex is also involved in the regulation of oncogenes transcription, such…”
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Abstract 4551: Impairment of c-kit expression in human cancer cell lines by a novel pharmacophoric unit selected for the recognition of the proto-oncogene KIT promotorial region
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract G-quadruplex structures at telomeric region and in oncogene promotorial sequences represent promising chemotherapeutic targets. Among these latter…”
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Development and Validation of the Acute PNeumonia Early Assessment Score for Safely Discharging Low-Risk SARS-CoV-2-Infected Patients from the Emergency Department
Published in Journal of clinical medicine (08-02-2022)“…A continuous demand for assistance and an overcrowded emergency department (ED) require early and safe discharge of low-risk severe acute respiratory syndrome…”
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Sequencing and G-Quadruplex Folding of the Canine Proto-Oncogene KIT Promoter Region: Might Dog Be Used as a Model for Human Disease?: e103876
Published in PloS one (01-08-2014)“…Downregulation of gene expression by induction of non-canonical DNA structures at promotorial level is a novel attractive anticancer strategy. In human, two…”
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14
Movimento de objetivação e subjetivação mediado pela criação artística
Published in Psico usf (01-12-2005)“…Este texto tem por objetivo refletir sobre o movimento de um sujeito e sua relação com a criação artística, apontando que neste processo articulam-se…”
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15
Association of cardiomyopathy and celiac disease: an almost diffuse but still less know entity. A review
Published in Archives of medical science (01-06-2008)“…Introduction: This study is a systematic revision of scientific articles regarding the epidemiological, clinical and therapeutic aspects of cardiomyopathy…”
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Processos de criação em educadoras: uma experiência e suas implicações
Published in Revista do Departamento de Psicologia - UFF (2007)“…Este trabalho busca analisar o processo de criação de uma atividade de produção literária, desenvolvida em um curso de formação para professores, intitulado…”
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17
Movimento de objetivação e subjetivação mediado pela criação artística
Published in Psico usf (01-12-2005)“…Este texto tem por objetivo refletir sobre o movimento de um sujeito e sua relação com a criação artística, apontando que neste processo articulam-se…”
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18
Contextos grupais e sujeitos em relação: contribuições às reflexões sobre grupos sociais
Published in Psicologia, reflexão e crítica (2002)“…A partir dos aportes teóricos da psicologia histórico-cultural considera-se que o sujeito se constitui/ é constituído em seus vários aspectos via processo de…”
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Processos de criação em educadoras: uma experiência e suas implicações
Published in Revista do Departamento de Psicologia - UFF (2007)“…Este trabalho busca analisar o processo de criação de uma atividade de produção literária, desenvolvida em um curso de formação para professores, intitulado…”
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20
Movimento de objetivação e subjetivação mediado pela criação artística Movement of objectivity and subjectivity, mediated for the artistic creation
Published in Psico usf (01-12-2005)“…Este texto tem por objetivo refletir sobre o movimento de um sujeito e sua relação com a criação artística, apontando que neste processo articulam-se…”
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