Search Results - "Da Costa Neves Ferreira, Ana Gisele"
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Differential proteomic comparison of breast cancer secretome using a quantitative paired analysis workflow
Published in BMC cancer (18-04-2019)“…Worldwide, breast cancer is the main cause of cancer mortality in women. Most cases originate in mammary ductal cells that produce the nipple aspirate fluid…”
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Heterologous expression of the antimyotoxic protein DM64 in Pichia pastoris
Published in PLoS neglected tropical diseases (31-07-2017)“…Snakebite envenomation is a neglected condition that constitutes a public health problem in tropical and subtropical countries, including Brazil…”
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Identification of Novel Genes and Proteoforms in Angiostrongylus costaricensis through a Proteogenomic Approach
Published in Pathogens (Basel) (31-10-2022)“…RNA sequencing (RNA-Seq) and mass-spectrometry-based proteomics data are often integrated in proteogenomic studies to assist in the prediction of eukaryote…”
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Revisiting the Therapeutic Potential of Bothrops jararaca Venom: Screening for Novel Activities Using Connectivity Mapping
Published in Toxins (06-02-2018)“…Snake venoms are sources of molecules with proven and potential therapeutic applications. However, most activities assayed in venoms (or their components) are…”
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Proteogenomics Reveals Orthologous Alternatively Spliced Proteoforms in the Same Human and Mouse Brain Regions with Differential Abundance in an Alzheimer's Disease Mouse Model
Published in Cells (Basel, Switzerland) (23-06-2021)“…Alternative splicing (AS) may increase the number of proteoforms produced by a gene. Alzheimer's disease (AD) is a neurodegenerative disease with…”
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Using mass spectrometry to explore the neglected glycan moieties of the antiophidic proteins DM43 and DM64
Published in Proteomics (Weinheim) (01-08-2012)“…The resistance of the opossum Didelphis aurita to Bothrops snake venoms is attributed to the opossum's antihemorrhagic (DM43) and antimyotoxic (DM64) acidic…”
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Potential correlation between tumor aggressiveness and protein expression patterns of nipple aspirate fluid (NAF) revealed by gel-based proteomic analysis
Published in Current topics in medicinal chemistry (01-02-2014)“…Breast cancer is the leading cause of cancer related deaths in women. Most breast cancers stem from mammary ductal cells that secrete nipple aspirate fluid…”
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The phosphate-starvation response in Vibrio cholerae O1 and phoB mutant under proteomic analysis: Disclosing functions involved in adaptation, survival and virulence
Published in Proteomics (Weinheim) (01-03-2006)“…A proteomic analysis of a wild‐type and of a phoB mutant showed that Vibrio cholerae expresses genes of two major regulons in response to phosphate starvation…”
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XPlex: An Effective, Multiplex Cross-Linking Chemistry for Acidic Residues
Published in Analytical chemistry (Washington) (15-05-2018)“…Cross-linking/Mass spectrometry (XLMS) is a consolidated technique for structural characterization of proteins and protein complexes. Despite its success, the…”
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SpliceProt 2.0: A Sequence Repository of Human, Mouse, and Rat Proteoforms
Published in International journal of molecular sciences (01-01-2024)“…SpliceProt 2.0 is a public proteogenomics database that aims to list the sequence of known proteins and potential new proteoforms in human, mouse, and rat…”
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Disorders on cardiovascular parameters in rats and in human blood cells caused by Lachesis acrochorda snake venom
Published in Toxicon (Oxford) (01-09-2020)“…In Colombia, Lachesis acrochorda causes 2–3% of all snake envenomations. The accidents promote a high mortality rate (90%) due to blood and cardiovascular…”
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Proteomic profiling of nipple aspirate fluid (NAF): Exploring the complementarity of different peptide fractionation strategies
Published in Journal of proteomics (18-03-2015)“…NAF is a breast fluid that is closely related to the tumor microenvironment and a valuable sample for studying breast cancer. To perform an in-depth proteomic…”
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Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis
Published in Memórias do Instituto Oswaldo Cruz (01-09-2012)“…Angiostrongylus costaricensis is a nematode that causes abdominal angiostrongyliasis, a widespread human parasitism in Latin America. This study aimed to…”
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Integrative structural analysis of the antihemorrhagic protein DM43 and its target toxins BaP1 and jararhagin
Published in Toxicon (Oxford) (05-10-2019)Get full text
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Molecular mapping of BJ46a / jararhagin complex by mass spectrometry
Published in Toxicon (Oxford) (05-10-2019)Get full text
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Investigating the molecular basis of Bothrops asper venom resistance in the Colombian opossum Didelphis marsupialis
Published in Toxicon (Oxford) (05-10-2019)Get full text
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Structural analysis of a myotoxin-antimyotoxin complex by cross-linking, mass spectrometry, and bioinformatics
Published in Toxicon (Oxford) (01-02-2019)Get full text
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Identification of Novel Genes and Proteoforms in IAngiostrongylus costaricensis/I through a Proteogenomic Approach
Published in Pathogens (Basel) (01-10-2022)“…RNA sequencing (RNA-Seq) and mass-spectrometry-based proteomics data are often integrated in proteogenomic studies to assist in the prediction of eukaryote…”
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Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol
Published in Journal of experimental therapeutics & oncology (2008)“…Perillyl alcohol (POH) is a naturally occurring monoterpene with antiangiogenic and anti-tumoral properties. This chemotherapeutic agent has proven…”
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