Search Results - "Da Costa Neves, Patrícia Cristina"

Aptamers as Delivery Agents of siRNA and Chimeric Formulations for the Treatment of Cancer by Dinis Ano Bom, Ana Paula, da Costa Neves, Patrícia Cristina, Bonacossa de Almeida, Carlos Eduardo, Silva, Dilson, Missailidis, Sotiris

“…Both aptamers and siRNA technologies have now reached maturity, and both have been validated with a product in the market. However, although pegaptanib reached…”
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Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A by Azamor, Tamiris, da Silva, Andréa Marques Vieira, Melgaço, Juliana Gil, Dos Santos, Ana Paula, Xavier-Carvalho, Caroline, Alvarado-Arnez, Lucia Elena, Batista-Silva, Leonardo Ribeiro, de Souza Matos, Denise Cristina, Bayma, Camilla, Missailidis, Sotiris, Ano Bom, Ana Paula Dinis, Moraes, Milton Ozorio, da Costa Neves, Patrícia Cristina

“…The yellow fever vaccine (YF17DD) is highly effective with a single injection conferring protection for at least 10 years. The YF17DD induces polyvalent…”
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Recombinant yellow fever viruses elicit CD8+ T cell responses and protective immunity against Trypanosoma cruzi by Nogueira, Raquel Tayar, Nogueira, Alanderson Rocha, Pereira, Mirian Claudia Souza, Rodrigues, Maurício Martins, Neves, Patrícia Cristina da Costa, Galler, Ricardo, Bonaldo, Myrna Cristina

“…Chagas' disease is a major public health problem affecting nearly 10 million in Latin America. Despite several experimental vaccines have shown to be…”
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Decidual production of interferon lambda in response to ZIKV persistence: Clinical evidence and in vitro modelling by Azamor, Tamiris, Cunha, Daniela Prado, Nobre Pires, Keyla Silva, Lira Tanabe, Eloiza Lopes, Melgaço, Juliana Gil, Vieira da Silva, Andréa Marques, Ribeiro-Alves, Marcelo, Calvo, Thyago Leal, Tubarão, Luciana Neves, da Silva, Jane, Fernandes, Camilla Bayma, Fonseca de Souza, Alessandro, Torrentes de Carvalho, Amanda, Avvad-Portari, Elyzabeth, da Cunha Guida, Letícia, Gomes, Leonardo, Lopes Moreira, Maria Elisabeth, Dinis Ano Bom, Ana Paula, Cristina da Costa Neves, Patrícia, Missailidis, Sotiris, Vasconcelos, Zilton, Borbely, Alexandre Urban, Moraes, Milton Ozório

“…Zika virus (ZIKV) infections during pregnancy can result in Congenital Zika Syndrome (CZS), a range of severe neurological outcomes in fetuses that primarily…”
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TLR expression and NK cell activation after human yellow fever vaccination by da Costa Neves, Patrícia Cristina, de Souza Matos, Denise Cristina, Marcovistz, Rugimar, Galler, Ricardo

“…Abstract The yellow fever vaccine is very effective with a single injection conferring protection for at least 10 years. Recent evidence suggests that the…”
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Animal models and SARS-CoV-2-induced pulmonary and neurological injuries by Pinto, Marcelo Alves, da Silva, Alexandre Dos Santos, Rodrigues, Daniela Del Rosario Flores, Müller, Rodrigo, de Vasconcelos, Gentil Arthur Lins Bentes Mendonça, Neves, Patrícia Cristina da Costa, de Oliveira, Jaqueline Mendes, Marchevsky, Renato Sergio

“…Laboratory animals are essential mainly for experiments aiming to study pathogenesis and evaluate antivirals and vaccines against emerging human infectious…”
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Initial development of biosimilar immune checkpoint blockers using HEK293 cells by Ramos, Michael Bernardes, Araújo, Anna Erika Vieira de, Pestana, Cristiane Pinheiro, Ano Bom, Ana Paula Dinis, Bastos, Renata Chagas, de Almeida Oliveira, Aline, da Costa Neves, Patrícia Cristina, da Silva Junior, Haroldo Cid

“…Antibodies that block interaction of immune checkpoint receptors with its ligands have revolutionized the treatment of several cancers. Despite the success of…”
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Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model by Matos, Ada da Silva, Soares, Isabela Ferreira, Rodrigues-da-Silva, Rodrigo Nunes, Rodolphi, Cinthia Magalhães, Albrecht, Letusa, Donassolo, Rafael Amaral, Lopez-Camacho, Cesar, Ano Bom, Ana Paula Dinis, Neves, Patrícia Cristina da Costa, Conte, Fernando de Paiva, Pratt-Riccio, Lilian Rose, Daniel-Ribeiro, Cláudio Tadeu, Totino, Paulo Renato Rivas, Lima-Junior, Josué da Costa

“…In the Americas, is the predominant causative species of malaria, a debilitating and economically significant disease. Due to the complexity of the malaria…”
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Identification and validation of specific B-cell epitopes of hantaviruses associated to hemorrhagic fever and renal syndrome by Conte, Fernando de Paiva, Tinoco, Bianca Corrêa, Santos Chaves, Thiago, Oliveira, Renata Carvalho de, Figueira Mansur, Janaina, Mohana-Borges, Ronaldo, Lemos, Elba Regina Sampaio de, Neves, Patricia Cristina da Costa, Rodrigues-da-Silva, Rodrigo Nunes

“…Orthohantavirus infection is a neglected global health problem affecting approximately 200,000 people/year, spread by rodent hosts and associated to fatal…”
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Congenital Zika Syndrome Is Associated With Interferon Alfa Receptor 1 by Azamor, Tamiris, Cunha, Daniela Prado, da Silva, Andréa Marques Vieira, Bezerra, Ohanna Cavalcanti de Lima, Ribeiro-Alves, Marcelo, Calvo, Thyago Leal, Kehdy, Fernanda de Souza Gomes, Manta, Fernanda Saloum de Neves, Pinto, Thiago Gomes de Toledo, Ferreira, Laís Pereira, Portari, Elyzabeth Avvad, Guida, Letícia da Cunha, Gomes, Leonardo, Moreira, Maria Elisabeth Lopes, de Carvalho, Elizeu Fagundes, Cardoso, Cynthia Chester, Muller, Marcelo, Ano Bom, Ana Paula Dinis, Neves, Patrícia Cristina da Costa, Vasconcelos, Zilton, Moraes, Milton Ozório

“…Host factors that influence Congenital Zika Syndrome (CZS) outcome remain elusive. Interferons have been reported as the main antiviral factor in Zika and…”
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Different aspects of platelet evaluation in dengue: Measurement of circulating mediators, ability to interact with the virus, the degree of activation and quantification of intraplatelet protein content by Barros, Tamiris Azamor da Costa, Batista, Débora de Oliveira, Torrentes de Carvalho, Amanda, Costa Faria, Nieli Rodrigues da, Barreto-Vieira, Débora Ferreira, Jácome, Fernanda Cunha, Barth, Ortrud Monika, Nogueira, Rita Maria Ribeiro, Neves, Patrícia Cristina da Costa, Matos, Denise Cristina de Souza, Leal de Azeredo, Elzinandes, Vieira Damasco, Paulo, Cunha, Rivaldo Venâncio da, de-Oliveira-Pinto, Luzia Maria

“…•CD62P, NO and TBX2 ratio in platelet count may be predictors of dengue outcome.•Platelets undergo morphological activation with increase of CD62P in…”
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Interferon-lambda 3 and 4 Polymorphisms Increase Sustained Virological Responses and Regulate Innate Immunity in Antiviral Therapy With Pegylated Interferon-Alpha by da Silva, Andréa Marques Vieira, Alvarado-Arnez, Lucia Elena, Azamor, Tamiris, Batista-Silva, Leonardo Ribeiro, Leal-Calvo, Thyago, Bezerra, Ohanna Cavalcanti de Lima, Ribeiro-Alves, Marcelo, Kehdy, Fernanda de Souza Gomes, Neves, Patrícia Cristina da Costa, Bayma, Camilla, da Silva, Jane, de Souza, Alessandro Fonseca, Muller, Marcelo, de Andrade, Elisabete Ferreira, Andrade, Ana Carolina Magalhães, Dos Santos, Eliane Matos, Xavier, Janaína Reis, Maia, Maria De Lourdes De Sousa, Meireles, Rolando Páez, Cuni, Hugo Nodarse, Sander, Guilherme Becker, Picon, Paulo Dornelles, Matos, Denise C S, Moraes, Milton Ozório

“…Sustained virologic response (SVR) in chronic hepatitis C (CHC) treatment denotes that the host genetics controls the immune response and unequivocally…”
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Unleashing Fungicidal Forces: Exploring the Synergistic Power of Amphotericin B-Loaded Nanoparticles and Monoclonal Antibodies by Souza, Carla Soares de, Lopes, Victor Ropke da Cruz, Barcellos, Gabriel, Alexandrino-Junior, Francisco, Neves, Patrícia Cristina da Costa, Patricio, Beatriz Ferreira de Carvalho, Rocha, Helvécio Vinícius Antunes, Ano Bom, Ana Paula Dinis, Figueiredo, Alexandre Bezerra Conde

“…Fungal infections cause 1.7 million deaths annually, which can be attributed not only to fungus-specific factors, such as antifungal resistance and biofilm…”
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Evaluation of Two Adjuvant Formulations for an Inactivated Yellow Fever 17DD Vaccine Candidate in Mice by Cajaraville, Ana Carolina Dos Reis Albuquerque, Gomes, Mariana Pierre de Barros, Azamor, Tamiris, Pereira, Renata Carvalho, Neves, Patrícia Cristina da Costa, De Luca, Paula Mello, Lima, Sheila Maria Barbosa de, Gaspar, Luciane Pinto, Caride, Elena, Freire, Marcos da Silva, Medeiros, Marco Alberto

“…The attenuated yellow fever (YF) vaccine is one of the most successful vaccines ever developed. After a single dose administration YF vaccine can induce…”
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Correction: Recombinant Yellow Fever Viruses Elicit CD8+ T Cell Responses and Protective Immunity against Trypanosoma cruzi by Nogueira, Raquel Tayar, Nogueira, Alanderson Rocha, Pereira, Mirian Claudia Souza, Rodrigues, Maurício Martins, Neves, Patrícia Cristina da Costa, Galler, Ricardo, Bonaldo, Myrna Cristina

“…[This corrects the article DOI: 10.1371/journal.pone.0059347.]…”
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The role of immune subtyping in glioma mRNA vaccine development by Guterres, Alexandro, Abrahim, Mayla, da Costa Neves, Patrícia Cristina

“…Studies on the development of mRNA vaccines for central nervous system tumors have used gene expression profiles, clinical data and RNA sequencing from sources…”
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Biotechnological Evolution of siRNA Molecules: From Bench Tool to the Refined Drug by de Brito E Cunha, Danielle, Frederico, Ana Beatriz Teixeira, Azamor, Tamiris, Melgaço, Juliana Gil, da Costa Neves, Patricia Cristina, Bom, Ana Paula Dinis Ano, Tilli, Tatiana Martins, Missailidis, Sotiris

“…The depth and versatility of siRNA technologies enable their use in disease targets that are undruggable by small molecules or that seek to achieve a refined…”
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Cellular and Molecular Immunology Approaches for the Development of Immunotherapies against the New Coronavirus (SARS-CoV-2): Challenges to Near-Future Breakthroughs by Ano Bom, Ana Paula Dinis, da Costa Neves, Patricia Cristina, Monteiro, Robson Q., Gonçalves, Rafael Braga, Tubarão, Luciana Neves, da Silva, Andrea Marques Vieira, Azamor, Tamiris, Brito e Cunha, Danielle, Melgaço, Juliana Gil, Missailidis, Sotiris

“…The severe acute respiratory syndrome caused by the new coronavirus (SARS-CoV-2), termed COVID-19, has been highlighted as the most important infectious…”
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Inactivated and Immunogenic SARS-CoV-2 for Safe Use in Immunoassays and as an Immunization Control for Non-Clinical Trials by Gomes, Mariana Pierre de Barros, Linhares, José Henrique Rezende, Dos Santos, Tiago Pereira, Pereira, Renata Carvalho, Santos, Renata Tourinho, da Silva, Stephanie Almeida, Souza, Marta Cristina de Oliveira, da Silva, Juliana Fernandes Amorim, Trindade, Gisela Freitas, Gomes, Viviane Silva, Barreto-Vieira, Débora Ferreira, Carvalho, Milena Mouta Verdan França, Ano Bom, Ana Paula Dinis, Gardinali, Noemi Rovaris, Müller, Rodrigo, Alves, Nathalia Dos Santos, Moura, Luma da Cruz, Neves, Patrícia Cristina da Costa, Esteves, Gabriela Santos, Schwarcz, Waleska Dias, Missailidis, Sotiris, Mendes, Ygara da Silva, de Lima, Sheila Maria Barbosa

“…Successful SARS-CoV-2 inactivation allows its safe use in Biosafety Level 2 facilities, and the use of the whole viral particle helps in the development of…”
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Safety and immunogenicity of 17DD attenuated yellow fever vaccine in howler monkeys (Alouatta spp.) by Tavares da Silva Fernandes, André, Moreira, Silvia Bahadian, Gaspar, Luciane Pinto, Simões, Marisol, Cajaraville, Ana Carolina dos Reis Albuquerque, Pereira, Renata Carvalho, Gomes, Mariana Pierre de Barros, Linhares, José Henrique Rezende, Santos, Vanessa de Oliveira, Santos, Renata Tourinho, Amorim, Juliana Fernandes, Barros, Tamiris Azamor da Costa, Melgaço, Juliana Gil, Silva, Andréa Marques Vieira, Fernandes, Camilla Bayma, Tubarão, Luciana Neves, Silva, Jane, Caride, Elena Cristina, Borges, Maria Beatriz, Guimarães, Rosane Cuber, Marchevsky, Renato Sérgio, Lima, Sheila Maria Barbosa, Ano Bom, Ana Paula Dinis, Neves, Patrícia Cristina da Costa, Pissinatti, Alcides, Freire, Marcos da Silva

“…Background Alouatta spp. are highly susceptible to yellow fever (YF) infection and develop an often fatal disease. The threat posed by an outbreak started in…”
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