Search Results - "Da Silva, Laeticia"
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High-throughput and simultaneous quantitative analysis of homocysteine–methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC–MS/MS
Published in Analytical and bioanalytical chemistry (01-01-2017)“…The methionine cycle is a key pathway contributing to the regulation of human health, with well-established involvement in cardiovascular diseases and…”
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2
Urinary Metabolic Phenotyping Reveals Differences in the Metabolic Status of Healthy and Inflammatory Bowel Disease (IBD) Children in Relation to Growth and Disease Activity
Published in International journal of molecular sciences (11-08-2016)“…Growth failure and delayed puberty are well known features of children and adolescents with inflammatory bowel disease (IBD), in addition to the chronic course…”
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3
Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from Microcystis aeruguinosa PCC 7806
Published in Chemistry : a European journal (02-04-2013)“…By using the Telospot assay, 27 different extracts of cyanobacteria were evaluated for telomerase inhibition. All extracts showed varying, but significant…”
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4
Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains
Published in Metabolites (11-10-2013)“…Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological…”
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Balgacyclamides, Antiplasmodial Heterocyclic Peptides from Microcystis aeruguinosa EAWAG 251
Published in Journal of natural products (Washington, D.C.) (28-03-2014)“…The isolation and structural characterization of three new heterocyclic and macrocyclic peptides, balgacyclamides A–C, from Microcystis aeruginosa EAWAG 251…”
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6
Insulin Resistance during normal child growth and development is associated with a distinct blood metabolic phenotype (Earlybird 72)
Published in Pediatric diabetes (01-11-2019)“…Background While insulin resistance (IR) is associated with specific metabolite signatures in adults, there have been few truly longitudinal studies in healthy…”
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Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links
Published in PLoS genetics (01-02-2014)“…Metabolic traits are molecular phenotypes that can drive clinical phenotypes and may predict disease progression. Here, we report results from a metabolome-…”
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Consensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73)
Published in Scientific reports (23-01-2018)“…In longitudinal clinical studies, methodologies available for the analysis of multivariate data with multivariate methods are relatively limited. Here, we…”
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One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond
Published in Alzheimer's research & therapy (17-06-2017)“…Hyperhomocysteinemia is a risk factor for cognitive decline and dementia, including Alzheimer disease (AD). Homocysteine (Hcy) is a sulfur-containing amino…”
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10
High-Resolution Quantitative Metabolome Analysis of Urine by Automated Flow Injection NMR
Published in Analytical chemistry (Washington) (18-06-2013)“…Metabolism is essential to understand human health. To characterize human metabolism, a high-resolution read-out of the metabolic status under various…”
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Validation of the Brazilian Healthy Eating Index-Revised Using Biomarkers in Children and Adolescents
Published in Nutrients (30-01-2018)“…The Brazilian Healthy Eating Index-Revised (BHEI-R) can be used to determine overall dietary patterns. We assessed the BHEI-R scores in children and…”
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12
High-throughput method for the quantitation of metabolites and co-factors from homocysteine-methionine cycle for nutritional status assessment
Published in Bioanalysis (01-09-2016)“…There is increasing interest in the profiling and quantitation of methionine pathway metabolites for health management research. Currently, several analytical…”
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13
Urinary metabolomics in term newborns delivered spontaneously or with cesarean section: preliminary data
Published in Journal of pediatric and neonatal individualized medicine (01-10-2018)“…Introduction: In the last years the uncritical attitude towards cesarean section (CS) has been associated with the fast emergence of ‘modern’ diseases such as…”
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Metabonomics in neonatal nutrition research
Published in Journal of pediatric and neonatal individualized medicine (01-10-2015)“…Maternal obesity and early post-natal nutrition might associate with increased obesity risk in later life. We have investigated the effect of breastfeeding and…”
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15
Impact of breast-feeding and high- and low-protein formula on the metabolism and growth of infants from overweight and obese mothers
Published in Pediatric research (01-04-2014)“…Background: The combination of maternal obesity in early pregnancy and high protein intake in infant formula feeding might predispose to obesity risk in later…”
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ONE-CARBON METABOLISM, COGNITIVE IMPAIRMENT AND CSF MARKERS OF ALZHEIMER PATHOLOGY: HOMOCYSTEINE AND BEYOND
Published in Alzheimer's & dementia (01-07-2017)Get full text
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Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links: e1004132
Published in PLoS genetics (01-02-2014)“…Metabolic traits are molecular phenotypes that can drive clinical phenotypes and may predict disease progression. Here, we report results from a metabolome-…”
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Journal Article