Search Results - "DZIK, Jolanta M."

The ancestry and cumulative evolution of immune reactions by Dzik, Jolanta M

“…The last two decades of study enriched greatly our knowledge of how the immune system originated and the sophisticated immune mechanisms of today's vertebrates…”
Get full text

Molecules released by helminth parasites involved in host colonization by Dzik, Jolanta M

“…Parasites are designed by evolution to invade the host and survive in its organism until they are ready to reproduce. Parasites release a variety of molecules…”
Get full text

Melatonin nephroprotective action in Zucker diabetic fatty rats involves its inhibitory effect on NADPH oxidase by Winiarska, Katarzyna, Dzik, Jolanta M., Labudda, Mateusz, Focht, Dorota, Sierakowski, Bartosz, Owczarek, Aleksandra, Komorowski, Lukasz, Bielecki, Wojciech

“…Excessive activity of NADPH oxidase (Nox) is considered to be of importance for the progress of diabetic nephropathy. The aim of the study was to elucidate the…”
Get full text

ERK1/2 pathway is involved in renal gluconeogenesis inhibition under conditions of lowered NADPH oxidase activity by Winiarska, Katarzyna, Jarzyna, Robert, Dzik, Jolanta M., Jagielski, Adam K., Grabowski, Michal, Nowosielska, Agata, Focht, Dorota, Sierakowski, Bartosz

“…The aim of this study was to elucidate the mechanisms involved in the inhibition of renal gluconeogenesis occurring under conditions of lowered activity of…”
Get full text

Monocyte/Macrophage: NK Cell Cooperation-Old Tools for New Functions by Wałajtys-Rode, Elżbieta, Dzik, Jolanta M

“…Monocyte/macrophage and natural killer (NK) cells are partners from a phylogenetic standpoint of innate immune system development and its evolutionary…”
Get more information

Nitric oxide metabolites in the urine of full-term and preterm infants by Dzik, Jolanta M, Dobrzan´ska, Anna, Gruszfeld, Dariusz, Walajtys-Rode, Elzbieta

“…Background : In newborn full‐term and preterm infants the urine nitrites and nitrates (NOx) were measured, in order to investigate the effects of different…”
Get full text

Metabolic evolutionary roots of the macrophage immune response in amoeba-bacteria interactions: The conserved role of hypoxia-induced Factor and AMP kinase by Dzik, Jolanta

“…The bacteria Legionella, being able to infect both macrophages and protozoans, reduce oxidative phosphorylation and induce glycolysis, which allows pathogens…”
Get full text

Trichinella spiralis infection affects p47(phox) protein expression in guinea-pig alveolar macrophages by Dzik, Jolanta M, Zieliński, Zbigniew, Gołos, Barbara, Wałajtys-Rode, Elzbieta

“…To establish whether NADPH oxidase activation, responsible for previously demonstrated Trichinella spiralis-induced respiratory burst, results from assembling…”
Get full text

Crystal Structures of Rat Thymidylate Synthase Inhibited by Tomudex, a Potent Anticancer Drug by Sotelo-Mundo, Rogerio R, Ciesla, Joanna, Dzik, Jolanta M, Rode, Wojciech, Maley, Frank, Maley, Gladys F, Hardy, Larry W, Montfort, William R

“…Two crystal structures of rat thymidylate synthase (TS) complexed with dUMP and the anticancer drug Tomudex (ZD1694) have been determined to resolutions of 3.3…”
Get full text

Trichinella spiralis infection affects p47phox protein expression in guinea-pig alveolar macrophages by Dzik, J.M, Zielinski, Z, Golos, B, Walajtys-Rode, E

“…To establish whether NADPH oxidase activation, responsible for previously demonstrated Trichinella spiralis-induced respiratory burst, results from assembling…”
Get full text

5-Substituted N 4-Hydroxy-2‘-deoxycytidines and Their 5‘-Monophosphates:  Synthesis, Conformation, Interaction with Tumor Thymidylate Synthase, and in Vitro Antitumor Activity by Felczak, Krzysztof, Miazga, Agnieszka, Poznański, Jarosław, Bretner, Maria, Kulikowski, Tadeusz, Dzik, Jolanta M, Gołos, Barbara, Zieliński, Zbigniew, Cieśla, Joanna, Rode, Wojciech

“…Convenient procedures are described for the synthesis of 5-substituted N 4-hydroxy-2‘-deoxycytidines 5a,b,d − h via transformation of the respective…”
Get full text

Early response of guinea‐pig lungs to Trichinella spiralis infection by Dzik, Jolanta M., Gołos, Barbara, Jagielska, ELżbieta, Kapała, Agnieszka, Wałajtys‐Rode, ELżbieta

“…Summary In order to assess immunological response, induced in guinea‐pig lungs by Trichinella spiralis, cellular infiltration into pulmonary alveolar space and…”
Get full text

2-Thio derivatives of dUrd and 5-fluoro-dUrd and their 5'-monophosphates: synthesis, interaction with tumor thymidylate synthase, and in vitro antitumor activity by Bretner, Maria, Kulikowski, Tadeusz, Dzik, Jolanta M, Balinska, Malgorzata, Rode, Wojciech, Shugar, David

“…A convenient synthesis of 5-fluoro-2-thiouracil (11) is based on hydrolytic deamination of 5-fluoro-2-thiocytosine (9). Lewis acid-catalyzed condensation of…”
Get full text

Sulfamide antifolates inhibiting thymidylate synthase: synthesis, enzyme inhibition and cytotoxicity by Pawełczak, Krzysztof, Makowski, Maciej, Kempny, Michał, Dzik, Jolanta M, Gołos, Barbara, Rode, Wojciech, Rzeszotarska, Barbara

“…Synthesis and biological evaluation are described of seven new analogues (3-9) of two potent thymidylate synthase inhibitors, 10-propargyl-5,8-dideazafolate…”
Get full text

Synthesis and biological activity of N(alpha)-[4-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-propargylamino]phenylacetyl]-L-glutamic acid by Kusakiewicz-Dawid, Anna, Bugaj, Marta, Dzik, Jolanta M, Gołos, Barbara, Wińska, Patrycja, Pawełczak, Krzysztof, Rzeszotarska, Barbara, Rode, Wojciech

“…2-Deamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) is a potent inhibitor of thymidylate synthase. Its analogue,…”
Get full text

Effect of cyclosporin A on immunological response in lungs of guinea pigs infected with Trichinella spiralis by Dzik, Jolanta M, Zieliński, Zbigniew, Gołos, Barbara, Jagielska, Elzbieta, Wranicz, Mariusz, Wałajtys-Rode, Elzbieta

“…The effects of cyclosporin A (CsA), a potent immunosuppressive drug with antiparasitic activity, on the innate immunological response in guinea pig lungs…”
Get full text

5-Substituted N4-Hydroxy-2‘-deoxycytidines and Their 5‘-Monophosphates:  Synthesis, Conformation, Interaction with Tumor Thymidylate Synthase, and in Vitro Antitumor Activity by FELCZAK, Krzysztof, MIAZGA, Agnieszka, POZNAńSKI, Jarosław, BRETNER, Maria, KULIKOWSKI, Tadeusz, DZIK, Jolanta M., GOłOS, Barbara, ZIELIńSKI, Zbigniew, CIEśLA, Joanna, RODE, Wojciech

Get full text

Mechanism of inhibition of mammalian tumor and other thymidylate synthases by N4-hydroxy-dCMP, N4-hydroxy-5-fluoro-dCMP, and related analogs by Rode, Wojciech, Zielinski, Zbigniew, Dzik, Jolanta M, Kulikowski, Tadeusz, Bretner, Maria, Kierdaszuk, Borys, Ciesla, Joanna, Shugar, David

“…N4-Hydroxy-dCMP (N4-OH-dCMP), N4-methoxy-dCMP (N4-OMe-dCMP), and their 5-fluoro congeners (syntheses of which are described) were all slow-binding inhibitors…”
Get full text

Trichinella spiralis infection affects p47 phox protein expression in guinea-pig alveolar macrophages by Dzik, Jolanta M., Zieliński, Zbigniew, Gołos, Barbara, Wałajtys-Rode, Elżbieta

“…To establish whether NADPH oxidase activation, responsible for previously demonstrated Trichinella spiralis-induced respiratory burst, results from assembling…”
Get full text

Glutamate metabolism in relation to glutamate transport in kidney cortex mitochondria of rabbit by Bryła, J, Dzik, J M

“…1. The metabolism of glutamate was followed by measurements of phosphoenolpyruvate production, aspartate synthesis and ammonia release, whereas the transport…”
Get more information