Search Results - "DZIARMAGA, Alison"

Canonical WNT signaling during kidney development by Iglesias, Diana M, Hueber, Pierre-Alain, Chu, LeeLee, Campbell, Robert, Patenaude, Anne-Marie, Dziarmaga, Alison J, Quinlan, Jacklyn, Mohamed, Othman, Dufort, Daniel, Goodyer, Paul R

“…The canonical WNT signaling pathway plays a crucial role in patterning of the embryo during development, but little is known about the specific developmental…”
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Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice by DZIARMAGA, Alison, ECCLES, Michael, GOODYER, Paul

“…The molecular mechanisms that set congenital nephron number are unknown. However, humans with modest suboptimal nephron number may be at increased risk for…”
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PAX2 Activates WNT4 Expression during Mammalian Kidney Development by Torban, Elena, Dziarmaga, Alison, Iglesias, Diana, Chu, Lee Lee, Vassilieva, Tatiana, Little, Melissa, Eccles, Michael, Discenza, Maria, Pelletier, Jerry, Goodyer, Paul

“…The transcription factor PAX2 is expressed during normal kidney development and is thought to influence outgrowth and branching of the ureteric bud. Mice with…”
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Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk by CLARK, Patsy, DZIARMAGA, Alison, ECCLES, Michael, GOODYER, Paul

“…In renal-coloboma syndrome (RCS), null mutations of the PAX2 gene cause renal hypoplasia due to a congenital deficit of nephrons; affected individuals may…”
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Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2 by Dziarmaga, Alison, Hueber, Pierre-Alain, Iglesias, Diana, Hache, Nancy, Jeffs, Aaron, Gendron, Nathalie, Mackenzie, Alex, Eccles, Michael, Goodyer, Paul

“…During fetal kidney development, the extent of ureteric bud (UB) branching will determine final nephron endowment for life. Nephron number varies widely among…”
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Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome by DZIARMAGA, Alison, CLARK, Patsy, STAYNER, Cherie, JULIEN, Jean Pierre, TORBAN, Elena, GOODYER, Paul, ECCLES, Michael

“…In humans, PAX2 haploinsufficiency causes renal-coloboma syndrome (RCS) involving eye abnormalities, renal hypoplasia, and renal failure in early life. The…”
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The Direct Economic Burden of Gout in an Elderly Canadian Population by Fischer, Aren, Cloutier, Michel, Goodfield, Jason, Borrelli, Richard, Marvin, Dawn, Dziarmaga, Alison

“…To estimate the direct healthcare cost and resource use from the public payer perspective between patients with incident gout and matched gout-free patients in…”
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Impact of reflex testing for EGFR mutations in non-squamous non–small cell lung cancer (NSCLC) by Cheema, Parneet Kaur, Victor, Charles, Dolley, Aastha, Dziarmaga, Alison

“…Abstract only…”
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Exploring the Distribution of Prescription for Sulfonylureas in Patients with Type 2 Diabetes According to Cardiovascular Risk Factors Within a Canadian Primary Care Setting by Farahani, Pendar, Khan, Shahriar, Oatway, Mark, Dziarmaga, Alison

“…A growing body of evidence generated from observational studies and meta-analyses has begun to illustrate the potential adverse cardiovascular (CV) risk…”
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Renal hypoplasia: lessons from Pax2 by Dziarmaga, Alison, Quinlan, Jacklyn, Goodyer, Paul

“…The functions of Pax2 during renal development are many. It organizes caudal descent of the nephric duct, emergence of the ureteric bud, branching…”
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PAX2 optimizes nephron number during kidney development by Dziarmaga, Alison

“…In normal human populations, nephron number varies widely from 300,000 to over one million nephrons per kidney. This dramatic range was once considered to have…”
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