Search Results - "DWYER, M. G"

Subcortical and Cortical Gray Matter Atrophy in a Large Sample of Patients with Clinically Isolated Syndrome and Early Relapsing-Remitting Multiple Sclerosis by BERGSLAND, N, HORAKOVA, D, DWYER, M. G, DOLEZAL, O, SEIDL, Z. K, VANECKOVA, M, KRASENSKY, J, HAVRDOVA, E, ZIVADINOV, R

“…Recent studies have shown that selective regional, but not global, GM atrophy occurs from clinical onset to conversion to clinically definite MS. Our aim was…”
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Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis by ZIVADINOV, R, REDER, A. T, FILIPPI, M, MINAGAR, A, STÜVE, O, LASSMANN, H, RACKE, M. K, DWYER, M. G, FROHMAN, E. M, KHAN, O

“…Disease-modifying agents (DMAs), including interferon beta (IFNbeta) and glatiramer acetate (GA), are the mainstays of long-term treatment of multiple…”
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Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS by ZIVADINOV, R, MARR, K, HUNT, K, ANDREWS, M, CARL, E, DWYER, M. G, HOJNACKI, D, WEINSTOCK-GUTTMAN, B, CUTTER, G, RAMANATHAN, M, BENEDICT, R. H. B, KENNEDY, C, ELFADIL, M, YEH, A. E, REUTHER, J, BROOKS, C

“…Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in patients with multiple sclerosis (MS). A subject is considered CCSVI positive if ≥…”
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Iron Deposition on SWI-Filtered Phase in the Subcortical Deep Gray Matter of Patients with Clinically Isolated Syndrome May Precede Structure-Specific Atrophy by HAGEMEIER, J, WEINSTOCK-GUTTMAN, B, BERGSLAND, N, HEININEN-BROWN, M, CARL, E, KENNEDY, C, MAGNANO, C, HOJNACKI, D, DWYER, M. G, ZIVADINOV, R

“…Increasing evidence suggests that iron deposition is present in the later stages of MS. In this study we examined abnormal phase values, indicative of…”
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Value of MR Venography for Detection of Internal Jugular Vein Anomalies in Multiple Sclerosis: A Pilot Longitudinal Study by ZIVADINOV, R, GALEOTTI, R, MAGNANO, C, SALVI, F, WEINSTOCK-GUTTMAN, B, ZAMBONI, P, HOJNACKI, D, MENEGATTI, E, DWYER, M. G, SCHIRDA, C, MALAGONI, A. M, MARR, K, KENNEDY, C, BARTOLOMEI, I

“…CCSVI was recently described in patients with MS. CCSVI is diagnosed noninvasively by Doppler sonography and invasively by catheter venography. We assessed the…”
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Increased tissue damage and lesion volumes in African Americans with multiple sclerosis by WEINSTOCK-GUTTMAN, B, RAMANATHAN, M, HASHMI, K, ABDELRAHMAN, N, HOJNACKI, D, DWYER, M. G, HUSSEIN, S, BERGSLAND, N, MUNSCHAUER, F. E, ZIVADINOV, R

“…African American (AA) patients with multiple sclerosis (MS) have more rapid disease progression and poorer responses to disease-modifying therapies than white…”
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Randomized study of interferon beta-1a, low-dose azathioprine, and low-dose corticosteroids in multiple sclerosis by Havrdova, E, Zivadinov, R, Krasensky, J, Dwyer, MG, Novakova, I, Dolezal, O, Ticha, V, Dusek, L, Houzvickova, E, Cox, JL, Bergsland, N, Hussein, S, Svobodnik, A, Seidl, Z, Vaneckova, M, Horakova, D

“…Background Studies evaluating interferon beta (IFNβ) for multiple sclerosis (MS) showed only partial efficacy. In many patients, IFNβ does not halt relapses or…”
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Evolution of different MRI measures in patients with active relapsing-remitting multiple sclerosis over 2 and 5 years: a case–control study by Horakova, D, Cox, J L, Havrdova, E, Hussein, S, Dolezal, O, Cookfair, D, Dwyer, M G, Seidl, Z, Bergsland, N, Vaneckova, M, Zivadinov, R

“…Background:There is growing evidence for the concept of multiple sclerosis (MS) as an inflammatory neurodegenerative disease, with a different pattern of…”
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Intra- and Extraluminal Structural and Functional Venous Anomalies in Multiple Sclerosis, as Evidenced by 2 Noninvasive Imaging Techniques by DOLIC, K, MARR, K, SIDDIQUI, A. H, HOJNACKI, D, WEINSTOCK-GUTTMAN, B, ZIVADINOV, R, VALNAROV, V, DWYER, M. G, CARL, E, KARMON, Y, KENNEDY, C, BROOKS, C, KILANOWSKI, C, HUNT, K

“…Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the main extracranial cerebrospinal venous routes that…”
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Gender-related differences in MS: a study of conventional and nonconventional MRI measures by Antulov, R, Weinstock-Guttman, B, Cox, JL, Hussein, S, Durfee, J, Caiola, C, Dwyer, MG, Bergsland, N, Abdelrahman, N, Stosic, M, Hojnacki, D, Munschauer, FE, Miletic, D, Zivadinov, R

“…Background Studies showed gender-associated differences in multiple sclerosis (MS) disease evolution and in the evolution of conventional magnetic resonance…”
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Comparison of Three Different Methods for Measurement of Cervical Cord Atrophy in Multiple Sclerosis by Zivadinov, R, Banas, A.C, Yella, V, Abdelrahman, N, Weinstock-Guttman, B, Dwyer, M.G

“…Evidence is mounting that spinal cord atrophy significantly correlates with disability in patients with multiple sclerosis (MS). The purpose of this work was…”
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Multimodal imaging in systemic lupus erythematosus patients with diffuse neuropsychiatric involvement by Zivadinov, R, Shucard, JL, Hussein, S, Durfee, J, Cox, JL, Bergsland, N, Dwyer, MG, Benedict, RHB, Ambrus, J, Shucard, DW

“…Objectives The objective of this paper is to investigate conventional and nonconventional brain magnetic resonance imaging (MRI) findings in systemic lupus…”
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Chronic cerebrospinal venous insufficiency and iron deposition on susceptibility-weighted imaging in patients with multiple sclerosis: a pilot case-control study by Zivadinov, R, Schirda, C, Dwyer, M G, Haacke, M E, Weinstock-Guttman, B, Menegatti, E, Heininen-Brown, M, Magnano, C, Malagoni, A M, Wack, D S, Hojnacki, D, Kennedy, C, Carl, E, Bergsland, N, Hussein, S, Poloni, G, Bartolomei, I, Salvi, F, Zamboni, P

“…Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular phenomenon recently described in multiple sclerosis (MS) that is characterized by stenoses…”
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Voxel-wise magnetization transfer imaging study of effects of natalizumab and IFNβ-1a in multiple sclerosis by Zivadinov, R, Dwyer, MG, Hussein, S, Carl, E, Kennedy, C, Andrews, M, Hojnacki, D, Heininen-Brown, M, Willis, L, Cherneva, M, Bergsland, N, Weinstock-Guttman, B

“…Objective: To determine the effects of intravenous natalizumab and intramuscular interferon beta-1a (IFNβ-1a) on the volume of white-matter (WM) lesions and…”
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No Association Between Conventional Brain MR Imaging and Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis by ZIVADINOV, R, CUTTER, G, WILLIS, L, CHERNEVA, M, KENNEDY, C, DWYER, M. G, WEINSTOCK-GUTTMAN, B, MARR, K, RAMANATHAN, M, BENEDICT, R. H. B, BERGSLAND, N, MORGAN, C, CARL, E, HOJNACKI, D, YEH, E. A

“…CCSVI has been reported to occur at high frequency in MS. Its significance in relation to MR imaging parameters also needs to be determined, both in patients…”
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Subcortical atrophy is associated with cognitive impairment in mild Parkinson disease: a combined investigation of volumetric changes, cortical thickness, and vertex-based shape analysis by Mak, E, Bergsland, N, Dwyer, M G, Zivadinov, R, Kandiah, N

“…The involvement of subcortical deep gray matter and cortical thinning associated with mild Parkinson disease remains poorly understood. We assessed cortical…”
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Semi-automatic brain region extraction (SABRE) reveals superior cortical and deep gray matter atrophy in MS by Carone, D.A., Benedict, R.H.B., Dwyer, M.G., Cookfair, D.L., Srinivasaraghavan, B., Tjoa, C.W., Zivadinov, R.

“…In multiple sclerosis (MS), atrophy occurs in various cortical and subcortical regions. However, it is unclear whether this is mostly due to gray (GM) or white…”
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CSF dynamics and brain volume in multiple sclerosis are associated with extracranial venous flow anomalies: a pilot study by Zamboni, P, Menegatti, E, Weinstock-Guttman, B, Schirda, C, Cox, J L, Malagoni, A M, Hojnacki, D, Kennedy, C, Carl, E, Dwyer, M G, Bergsland, N, Galeotti, R, Hussein, S, Bartolomei, I, Salvi, F, Ramanathan, M, Zivadinov, R

“…We previously reported unexpectedly robust associations between vascular haemodynamic (VH) anomalies in the principal extracranial cerebral veins, causing…”
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Evaluation of Leptomeningeal Contrast Enhancement Using Pre-and Postcontrast Subtraction 3D-FLAIR Imaging in Multiple Sclerosis by Zivadinov, R, Ramasamy, D P, Hagemeier, J, Kolb, C, Bergsland, N, Schweser, F, Dwyer, M G, Weinstock-Guttman, B, Hojnacki, D

“…Leptomeningeal contrast enhancement is found in patients with multiple sclerosis, though reported rates have varied. The use of 3D-fluid-attenuated inversion…”
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Brain Atrophy Is Associated with Disability Progression in Patients with MS followed in a Clinical Routine by Ghione, E, Bergsland, N, Dwyer, M G, Hagemeier, J, Jakimovski, D, Paunkoski, I, Ramasamy, D P, Silva, D, Carl, E, Hojnacki, D, Kolb, C, Weinstock-Guttman, B, Zivadinov, R

“…The assessment of brain atrophy in a clinical routine is not performed routinely in multiple sclerosis. Our aim was to determine the feasibility of brain…”
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