Search Results - "DVORAK, M"
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Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans
Published in Blood (14-03-2013)“…Eosinophils release their granule proteins extracellularly through exocytosis, piecemeal degranulation, or cytolytic degranulation. Findings in diverse human…”
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2
Evolutionary origins of the blood vascular system and endothelium
Published in Journal of thrombosis and haemostasis (01-06-2013)“…Summary Every biological trait requires both a proximate and evolutionary explanation. The field of vascular biology is focused primarily on proximate…”
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3
Estimating the timing of geophysical commitment to 1.5 and 2.0 °C of global warming
Published in Nature climate change (01-06-2022)“…Following abrupt cessation of anthropogenic emissions, decreases in short-lived aerosols would lead to a warming peak within a decade, followed by slow cooling…”
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4
DNA released by leukemic cells contributes to the disruption of the bone marrow microenvironment
Published in Oncogene (31-10-2013)“…Reciprocal interactions between a tumor and its microenvironment control expansion of tumor cells. Here we show a specific type of interaction in which blasts…”
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5
Why are tumour blood vessels abnormal and why is it important to know?
Published in British journal of cancer (24-03-2009)“…Tumour blood vessels differ from their normal counterparts for reasons that have received little attention. We report here that they are of at least six…”
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6
Lipid body-phagosome interaction in macrophages during infectious diseases: host defense or pathogen survival strategy?
Published in PLoS pathogens (01-07-2012)“…Phagocytosis of invading microorganisms by specialized cells such as macrophages and neutrophils is a key component of the innate immune response. These cells…”
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7
Detection and quantification of airborne inoculum of Hymenoscyphus pseudoalbidus using real‐time PCR assays
Published in Plant pathology (01-12-2014)“…A method based on real‐time polymerase chain reaction (PCR) and the use of rotating‐arm spore traps was developed for quantifying airborne Hymenoscyphus…”
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8
The Rick Hansen Spinal Cord Injury Registry (RHSCIR): a national patient-registry
Published in Spinal cord (01-01-2012)“…Study design: Development of a prospective patient registry. Objective: To develop a patient registry for persons with traumatic spinal cord injuries (SCI),…”
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9
VEGF-A and the induction of pathological angiogenesis
Published in Annual review of pathology (01-01-2007)“…Tumors, wounds, and chronic inflammatory disorders generate a new vascular supply by a process known as pathological angiogenesis. Whereas formation of the…”
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10
Physiological Changes in Extracellular Calcium Concentration Directly Control Osteoblast Function in the Absence of Calciotropic Hormones
Published in Proceedings of the National Academy of Sciences - PNAS (06-04-2004)“…We investigated the direct effects of changes in free ionized extracellular calcium concentrations ([ Ca2+] o) on osteoblast function and the involvement of…”
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11
Inhibition of the Akt/PKB Kinase Increases Nav1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons
Published in International journal of molecular sciences (01-02-2022)“…In neurons, changes in Akt activity have been detected in response to the stimulation of transmembrane receptors. However, the mechanisms that lead to changes…”
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12
Dimensional and Shape Analysis of Additively Manufactured Shaped Parts of DIEVAR Steel Moulds
Published in Archives of foundry engineering (01-01-2024)“…The paper presents the results of dimensional and shape analysis of additively manufactured shaped parts of foundry moulds; specifically, shaped gate valve…”
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13
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)
Published in PloS one (29-03-2018)“…The tumor microenvironment (TME) promotes tumor cell invasion and metastasis. An important step in the shift to a pro-cancerous microenvironment is the…”
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14
Diagnosis of ST-Elevation Myocardial Infarction in the Presence of Left Bundle Branch Block With the ST-Elevation to S-Wave Ratio in a Modified Sgarbossa Rule
Published in Annals of emergency medicine (01-12-2012)“…Study objective Sgarbossa's rule, proposed for the diagnosis of acute myocardial infarction in the presence of left bundle branch block, has had suboptimal…”
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15
Endoscopic ultrasound‐guided fine needle aspiration biopsy of pancreatic lesions. An 8‐year analysis of single institution material focusing on efficacy and learning progress
Published in Cytopathology (Oxford) (01-04-2017)“…Objective To evaluate the efficacy and the learning curve of the endoscopic ultrasound‐guided fine needle aspiration biopsy (EUS‐FNAB) diagnostics of…”
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Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
Published in Molecules (Basel, Switzerland) (24-07-2020)“…Disruption of protein:protein interactions (PPIs) that regulate the function of voltage-gated Na (Nav) channels leads to neural circuitry aberrations that have…”
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Development of Allosteric Modulators of Voltage-Gated Na + Channels: A Novel Approach for an Old Target
Published in Current topics in medicinal chemistry (01-01-2021)“…Given their primacy in governing the action potential (AP) of excitable cells, voltage-gated Na+ (Nav) channels are important pharmacological targets of…”
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18
Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins
Published in Journal of leukocyte biology (01-02-2008)“…Eosinophils generate and store a battery of proteins, including classical cationic proteins, cytokines, chemokines, and growth factors. Rapid secretion of…”
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Ultrastructural Studies of Human Basophils and Mast Cells
Published in Journal of Histochemistry & Cytochemistry (01-09-2005)“…Ultrastructural studies of human mast cells (HMCs) and basophils (HBs) are reviewed. Sources of HMCs include biopsies of tissue sites and in situ study of…”
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The Vesiculo-Vacuolar Organelle (VVO): A New Endothelial Cell Permeability Organelle
Published in The journal of histochemistry and cytochemistry (01-04-2001)“…A newly defined endothelial cell permeability structure, termed the Vesiculo–Vacuolar organelle (VVO), has been identified in the microvasculature that…”
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