Search Results - "DUTCHER, J. S"

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  1. 1

    Species differences in the disposition of inhaled butadiene by Bond, J A, Dahl, A R, Henderson, R F, Dutcher, J S, Mauderly, J L, Birnbaum, L S

    Published in Toxicology and applied pharmacology (01-07-1986)
    “…Recent chronic inhalation carcinogenicity studies of butadiene indicated that B6C3F1 mice are more sensitive to the tumorigenic effects of inhaled butadiene…”
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  2. 2

    Renal toxicity due to reactive metabolites formed in situ in the kidney: investigations with 4-ipomeanol in the mouse by Boyd, M R, Dutcher, J S

    “…The in vitro metabolism and covalent binding of the furan derivative, 4-ipomeanol, was mediated by oxygen-requiring, NADPH-dependent, CO-inhibitable microsomal…”
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  3. 3

    Uptake and excretion of [14C]methyl bromide as influenced by exposure concentration by Medinsky, M A, Dutcher, J S, Bond, J A, Henderson, R F, Mauderly, J L, Snipes, M B, Mewhinney, J A, Cheng, Y S, Birnbaum, L S

    Published in Toxicology and applied pharmacology (01-01-1985)
    “…Methyl bromide is a widely used soil fumigant and poses potential inhalation hazard to workers. Uptake of methyl bromide and pathways for excretion of 14C were…”
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  4. 4

    Disposition of [14C]methyl bromide in Fischer-344 rats after oral or intraperitoneal administration by Medinsky, M A, Bond, J A, Dutcher, J S, Birnbaum, L S

    Published in Toxicology (Amsterdam) (01-01-1984)
    “…Methyl bromide is used as a disinfectant to fumigate soil. The intent of our study was to determine the disposition of methyl bromide following a single acute…”
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  5. 5

    Disposition of [14C]2,3-dichloropropene in Fischer-344 rats after oral or intraperitoneal administration by Medinsky, M A, Bond, J A, Dutcher, J S, Birnbaum, L S

    Published in Toxicology letters (01-10-1984)
    “…2,3-Dichloropropene (2,3-DCP), a component of commercial fumigants and nematocides, was mixed with [14C]2,3-DCP and given to rats by peroral (p.o.) or…”
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  6. 6

    Fractionation of diesel particle extracts by sephadex LH-20 and thin-layer chromatography by Bechtold, W E, Dutcher, J S, Brooks, A L, Henderson, T R

    Published in Journal of applied toxicology (01-10-1985)
    “…A method was developed to concentrate fractions high in bacterial mutagenicity from diesel exhaust particle (DEP) extracts. The two-step fractionation of…”
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  7. 7

    Ipomeanol 4-glucuronide, a major urinary metabolite of 4-ipomeanol in the rat by Statham, C N, Dutcher, J S, Kim, S H, Boyd, M R

    Published in Drug metabolism and disposition (01-05-1982)
    “…Urinary excretion and metabolism of 4-ipomeanol was studied in rats injected ip with the radiolabeled compound. There was a rapid elimination of radioactivity…”
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  8. 8

    Fractionation, chemical analysis, and mutagenicity testing of low-Btu coal gasifier tar by Royer, R E, Mitchell, C E, Hanson, R L, Dutcher, J S, Bechtold, W E

    Published in Environmental research (01-08-1983)
    “…A tar from a low-Btu coal gasifier was subjected to parallel fractionation, chemical analysis, and bacterial mutagenicity (Salmonella) assay. Like other…”
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  9. 9

    Metabolism of 1-[14C]nitropyrene in isolated perfused rat livers by Bond, J A, Medinsky, M A, Dutcher, J S

    Published in Toxicology and applied pharmacology (30-09-1984)
    “…1-Nitropyrene (1-NP), a constituent of diesel exhaust, is carcinogenic to rats and is a bacterial and mammalian mutagen. Biliary and fecal excretion of 1-NP…”
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  10. 10

    Determination of plasma procainamide and N-acetylprocainamide concentration by high-pressure liquid chromatography by Dutcher, J S, Strong, J M

    Published in Clinical chemistry (Baltimore, Md.) (01-07-1977)
    “…We describe a routine method for determining concentrations of the antiarrhythmic drug procainamide and its active metabolite, N-acetylprocainamide, in plasma…”
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  11. 11

    Distribution and elimination of inhaled phenanthridone in Fischer-344 rats by Dutcher, J S, Mitchell, C E

    “…Aza-arenes are widely distributed in the environment. Certain members of this chemical class are biologically active and therefore could pose health hazards to…”
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  12. 12

    Binding of nitropyrenes and benzo[a]pyrene to mouse lung deoxyribonucleic acid after pretreatment with inducing agents by Howard, A J, Mitchell, C E, Dutcher, J S, Henderson, T R, McClellan, R O

    Published in Biochemical pharmacology (01-07-1986)
    “…In assessing the biological effects of exposure to a complex chemical mixture, it is important to determine how the behavior of one compound may be influenced…”
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  13. 13

    In vitro cytotoxicity to alveolar macrophages of tar from a low-Btu coal gasifier by Hill, J O, Royer, R E, Mitchell, C E, Dutcher, J S

    Published in Environmental research (1983)
    “…The cytotoxicity of fractions, subfractions, and some individual components present in tar from a low-Btu coal gasifier was determined in vitro with cultured…”
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  14. 14

    Mutagenicity of used crankcase oils from diesel and spark ignition automobiles by Dutcher, J S, Li, A P, McClellan, R O

    Published in Environmental research (01-06-1986)
    “…The Salmonella mutagenicity assay was used to compare the mutagenic activity of used crankcase oil (UCO) from diesel and spark-ignition (gasoline) engine…”
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  15. 15

    Detection of nitroaromatic compounds on coal combustion particles by Hanson, R L, Henderson, T R, Hobbs, C H, Clark, C R, Carpenter, R L, Dutcher, J S, Harvey, T M, Hunt, D F

    “…Mutagenic and nonmutagenic extracts of fly ash from fluidized bed combustion were analyzed to determine the compounds responsible for the direct mutagenic…”
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  16. 16

    Disposition and metabolism of 2,3-[14C]dichloropropene in rats after inhalation by Bond, J A, Medinsky, M A, Dutcher, J S, Henderson, R F, Cheng, Y S, Mewhinney, J A, Birnbaum, L S

    Published in Toxicology and applied pharmacology (30-03-1985)
    “…2,3-Dichloropropene (2,3-DCP) is a constituent of some commercially available preplant soil fumigants for the control of plant parasitic nematodes. Human…”
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  17. 17

    Chemical and biological characterization of volatile components of environmental samples after fractionation by vacuum line cryogenic distillation by HANSON, R. L, DAHL, A. R, ROTHENBERG, S. J, BENSON, J. M, BROOKS, A. L, DUTCHER, J. S

    “…Volatile components from diesel exhaust particles and coal gasifier process gas condensate were vacuum fractionated by cryogenic distillation and identified by…”
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  18. 18

    Contribution of primary aromatic amines to the mutagenicity of gasifier tars and coal oils by Bechtold, W E, Dutcher, J S, Brooks, A L, Henderson, R F

    Published in Mutation research (01-01-1985)
    “…Two reactions that chemically alter primary aromatic amines (PAA) were used to assess the contribution of these compounds to the indirect bacterial…”
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  19. 19

    Generation and characterization of radiolabeled diesel exhaust by Dutcher, J S, Sun, J D, Lopez, J A, Wolf, I, Wolff, R K, McClellan, R O

    “…To evaluate the potential health risks associated with increased use of diesel engines, information is needed on the biological fate of inhaled diesel exhaust…”
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  20. 20

    A sensitive and specific assay for pentamethylmelamine in plasma: applicability to clinical studies by Dutcher, J S, Jones, R B, Boyd, M R

    Published in Cancer treatment reports (01-01-1980)
    “…A sensitive and specific procedure for measuring plasma levels of pentamethylmelamine (PMM), a chemotherapeutic agent currently undergoing phase I trials, has…”
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