Search Results - "DUSSO, A. S"

Mechanism of vitamin D action and its regulation by Dusso, AS, Brown, AJ

“…Most of the biological actions of 1,25(OH)2D3, the hormonal form of vitamin D, are mediated by the vitamin D receptor (VDR), a member of the steroid/thyroid…”
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Recombinant human erythropoietin (rHuEPO) increases endothelin-1 release by endothelial cells by Carlini, Raul G., Dusso, Adriana S., Obialo, Chamberlain I., Alvarez, Ulises M., Rothstein, Marcos

“…Recombinant human erythropoietin (rHuEPO) increases endothelin-1 release by endothelial cells. Hypertension is a major complication of rHuEPO therapy in…”
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Phosphorus restriction reverses hyperparathyroidism in uremia independent of changes in calcium and calcitriol by Lopez-Hilker, S, Dusso, A S, Rapp, N S, Martin, K J, Slatopolsky, E

“…Phosphorus is a well-known modulator of renal 1 alpha-hydroxylase activity. In early and moderate renal failure it is proposed that dietary Pi reduction…”
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On the mechanisms for the selective action of vitamin D analogs by Dusso, A S, Negrea, L, Gunawardhana, S, Lopez-Hilker, S, Finch, J, Mori, T, Nishii, Y, Slatopolsky, E, Brown, A J

“…A variety of analogs of 1,25-(OH)2D3 with less calcemic activity and lower receptor binding affinity than 1,25-(OH)2D3 have been developed. However, these…”
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Pathogenic mechanisms for parathyroid hyperplasia by Dusso, A.S., Sato, T., Arcidiacono, M.V., Alvarez-Hernandez, D., Yang, J., Gonzalez-Suarez, I., Tominaga, Y., Slatopolsky, E.

“…Parathyroid hyperplasia is the cause of parathyroid gland enlargement in kidney disease (KD). Hypocalcemia, hyperphosphatemia, and vitamin D deficiency are…”
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Extrarenal production of calcitriol in normal and uremic humans by Dusso, A S, Finch, J, Brown, A, Ritter, C, Delmez, J, Schreiner, G, Slatopolsky, E

“…We have previously reported low serum levels of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] and increased 1,25-(OH)2D3 production after the administration of…”
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Stat1-Vitamin D Receptor Interactions Antagonize 1,25-Dihydroxyvitamin D Transcriptional Activity and Enhance Stat1-Mediated Transcription by Vidal, Marcos, Ramana, Chilakamarti V., Dusso, Adriana S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A new analog of 1,25-(OH)2D3, 19-NOR-1,25-(OH)2D2, suppresses serum PTH and parathyroid gland growth in uremic rats without elevation of intestinal vitamin D receptor content by Takahashi, F, Finch, J L, Denda, M, Dusso, A S, Brown, A J, Slatopolsky, E

“…We have previously reported that 19-nor-1,25-(OH)2D2, a new analog of 1,25-(OH)2D3, suppresses parathyroid hormone (PTH) secretion in uremic rats in the…”
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gamma-Interferon-induced resistance to 1,25-(OH)2 D3 in human monocytes and macrophages: a mechanism for the hypercalcemia of various granulomatoses by Dusso, A S, Kamimura, S, Gallieni, M, Zhong, M, Negrea, L, Shapiro, S, Slatopolsky, E

“…The hypercalcemia of various granulomatoses is caused by endogenous 1,25-dihydroxyvitamin D [1,25-(OH)2D3] overproduction by disease-activated macrophages. The…”
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The effect of 22-oxacalcitriol on serum calcitriol by Dusso, A S, Negrea, L, Finch, J, Kamimura, S, Lopez-Hilker, S, Mori, T, Nishii, Y, Brown, A, Slatopolsky, E

“…1,25-Dihydroxyvitamin D3 (1,25D) regulates its own levels in circulation by affecting its rates of synthesis and degradation, 22-Oxacalcitriol (OCT), a vitamin…”
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Vitamin D analogues for secondary hyperparathyroidism by Brown, Alex J., Dusso, Adriana S., Slatopolsky, Eduardo

“…Secondary hyperparathyroidism (2HPT), a common disorder in patients with chronic renal failure, develops in response to phosphate retention and low serum…”
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p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth by Dusso, A S, Pavlopoulos, T, Naumovich, L, Lu, Y, Finch, J, Brown, A J, Morrissey, J, Slatopolsky, E

“…The parathyroid (PT) hyperplasia induced by renal failure can be further enhanced by high dietary phosphate (P) or completely abolished by P restriction. To…”
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1,25-Dihydroxyvitamin D synthesis in rat liver microsomes by Negrea, L A, Slatopolsky, E, Dusso, A S

“…Previous studies from our laboratory have shown 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] production by rat liver homogenates and a low affinity of the hepatic…”
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Modulation of renal osteodystrophy by extrarenal production of calcitriol by Delmez, J A, Dusso, A S, Slatopolsky, E, Teitelbaum, S L

“…We report a patient with severe chronic renal failure who developed spontaneous bone fractures. He was found to have hypercalcemia, normal calcitriol levels…”
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The effect of 1 alpha, 25-dihydroxycholecalciferol on iron metabolism by Dusso, A S, Puche, R C

“…Chronic administration of hypercalcemic doses of 1 alpha, 25-dihydroxycholecalciferol to intact, vitamin-D repleted rats for 4 weeks, enhanced net intestinal…”
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Genetic conditioning of the response of rat bone tissue to estradiol by HINRICHSEN, L. I, DUSSO, A. S, BERLI, D, PUCHE, R. C

“…The effects of the administration of pharmacological doses of estradiol were studied in two genetically different lines of inbred rats, at two stages of…”
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Role of calcium-phosphate product and bone-associated proteins on vascular calcification in renal failure by COZZOLINO, Mario, DUSSO, Adriana S, SLATOPOLSKY, Eduardo

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Vitamin D by Dusso, Adriana S, Brown, Alex J, Slatopolsky, Eduardo

“…The vitamin D endocrine system plays an essential role in calcium homeostasis and bone metabolism, but research during the past two decades has revealed a…”
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Maternal effects on the phenotypic expression of the skeletal store of calcium (bone mass) and related variables in the rat by Puche, R C, Hinrichsen, L I, Dusso, A S

“…The phenotypic expression of bone mass and several related variables were investigated in the rat, assessing the differences and resemblances between two…”
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The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion by Nishii, Y, Abe, J, Mori, T, Brown, A J, Dusso, A S, Finch, J, Lopez-Hilker, S, Morrissey, J, Slatopolsky, E

“…OCT, a non-calcemic analogue of 1,25(OH)2D3 has been found to have a more potent activity than that of 1,25(OH)2D3 regarding cell differentiation and…”
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