Search Results - "DUSKOVA, Martina"

Combined Cancer Immunotherapy Against Aurora Kinase A by Kastankova, Iva, Polakova, Ingrid, Duskova, Martina, Smahel, Michal

“…Aurora kinase A (AURKA) is a centrosomal protein that is overexpressed in a number of human malignancies and can contribute to tumor progression. As we used…”
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DNA vaccine against human papillomavirus type 16: Modifications of the E6 oncogene by POLAKOVA, Ingrid, POKORNA, Dana, DUSKOVA, Martina, SMAHEL, Michal

“…Abstract Since its discovery, DNA vaccination has become an effective strategy for the development of vaccines against cancer including cervical carcinoma…”
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Antitumor DNA vaccination against the Sox2 transcription factor by POLAKOVA, INGRID, DUSKOVA, MARTINA, SMAHEL, MICHAL

“…As cancer stem cells (CSCs) are resistant to chemotherapy, radiotherapy and targeted molecular therapy, immunotherapy of tumors could be aimed at their…”
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Vaccination with human papillomavirus type 16-derived peptides using a tattoo device by Pokorná, Dana, Poláková, Ingrid, Kindlová, Martina, Dušková, Martina, Ludvíková, Viera, Gabriel, Pavel, Kutinová, Lud’a, Müller, Martin, Šmahel, Michal

“…Abstract Tattooing has been shown to be very efficient at inducing immunity by vaccination with DNA vaccines. In this study, we examined the usability of…”
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Enhancement of DNA vaccine potency against legumain by Smahel, Michal, Duskova, Martina, Polakova, Ingrid, Musil, Jan

“…The asparaginyl endopeptidase legumain that is overexpressed in M2-polarized tumor-associated macrophages has been identified as a suitable target for…”
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Predictive value of serum cytokine levels in chronic myeloid leukemia patients by Petrackova, Martina, Hamsikova, Eva, Duskova, Martina, Ptackova, Pavlina, Klamova, Hana, Humlova, Zuzana, Vonka, Vladimir

“…Highlights • Cytokine levels in CML patients at diagnosis and therapy outcome were related. • MCP-1 levels were significantly higher in patients with optimal…”
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Enhancement of T cell-mediated and humoral immunity of β-glucuronidase-based DNA vaccines against HPV16 E7 oncoprotein by SMAHEL, Michal, POLAKOVA, Ingrid, POKORNA, Dana, LUDVIKOVA, Viera, DUSKOVA, Martina, VLASAK, Josef

“…Therapeutic DNA vaccines against oncogenic infection with human papillomavirus type 16 (HPV16) are mostly targeted against viral oncoproteins E7 and E6. To…”
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Intracellular Cytokines Produced by Stimulated CD3+ Cells from Chronic Myeloid Leukemia Patients by Ptackova, Pavlina, Petrackova, Martina, Hindos, Miroslav, Duskova, Martina, Hamsikova, Eva, Klamova, Hana, Pecherkova, Pavla, Humlova, Zuzana, Vonka, Vladimir

“…Our work examined the production of intracellular interferon (INF)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-2, and IL-4 by in vitro stimulated CD3+…”
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Kynurenine and uric acid levels in chronic myeloid leukemia patients by Vonka, Vladimir, Humlova, Zuzana, Klamova, Hana, Kujovska-Krcmova, Lenka, Petrackova, Martina, Hamsikova, Eva, Krmencikova-Fliegl, Monika, Duskova, Martina, Roth, Zdenek

“…Indoleamine 2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan 2,3-dioxygenase (TDO) represent some of the key immune regulators. Their increased activity has been…”
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Expression of a recombinant Human papillomavirus 16 E6GT oncoprotein fused to N- and C-termini of Potato virus X coat protein in Nicotiana benthamiana by Cerovska, Noemi, Moravec, Tomas, Hoffmeisterova, Hana, Plchova, Helena, Synkova, Helena, Polakova, Ingrid, Duskova, Martina, Smahel, Michal

“…Infection with Human papillomaviruses (HPVs) is linked to cervical cancer, which is one of the most common cancers found among women worldwide. Despite…”
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Live cell vaccines expressing B7.1, monocyte chemoattractant protein 1 and granulocyte-macrophage colony stimulation factor derived from mouse HPV16-transformed cells by LAKATOSOVA-ANDELOVA, Monika, JINOCH, Pavel, DUSKOVA, Martina, MARINOV, Iuri, VONKA, Vladimir

“…One of the gene therapy strategies in oncology is immunization with cancer cells that express various cytokines. We used a thymidine-kinase deficient (cTK-)…”
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Combined immunization with fusion genes of mutated E7 gene of human papillomavirus type 16 did not enhance antitumor effect by Pokorná, Dana, Macková, Jana, Dusková, Martina, Rittich, Simon, Ludvíková, Viera, Smahel, Michal

“…Background The E7 oncoprotein of human papillomavirus type 16 (HPV16) is frequently used as a model tumor‐associated antigen. Its immunogenicity has been…”
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DNA vaccination against bcr-abl-positive cells in mice by LUCANSKY, Vincent, SOBOTKOVA, Eva, TACHEZY, Ruth, DUSKOVA, Martina, VONKA, Vladimir

“…A series of DNA vaccines based on the bcr-abl fusion gene were developed and tested in mice. Two mouse (BALB/c) bcr-abl-transformed cell lines, B210 and 12B1,…”
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Effects of endostatin production on oncogenicity and metastatic activity of HPV16-transformed mouse cells: Role of interleukin 1α by LAKATOSOVA-ANDELOVA, Monika, DUSKOVA, Martina, LUCANSKY, Vincent, PARAL, Petr, VONKA, Vladimir

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Combined chemo-and immunotherapy of tumors induced in mice by bcr-abl-transformed cells by SOBOTKOVA, Eva, DUSKOVA, Martina, TACHEZY, Ruth, PETRACKOVA, Martina, VONKA, Vladimir

“…For our experiments we selected two oncogenic, bcr-abl-transformed mouse cell lines, viz. B210 and 12B1. Both cell types are capable of inducing leukemia-like…”
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Efficacy of reovirus therapy combined with cyclophosphamide and gene-modified cell vaccines on tumors induced in mice by HPV16-transformed cells by SOBOTKOVA, Eva, DUSKOVA, Martina, ECKSCHLAGER, Tomas, VONKA, Vladimir

“…Oncolytic virotherapy is a novel approach to cancer treatment. In the present study we tested the ability of reovirus type 3, strain Dearing, to suppress the…”
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Effects of endostatin production on oncogenicity and metastatic activity of HPV16-transformed mouse cells: role of interleukin 1alpha by Lakatosova-Andelova, Monika, Duskova, Martina, Lucansky, Vincent, Paral, Petr, Vonka, Vladimir

“…Two mouse HPV16-transformed cell lines, viz. MK16 cells, which induce metastasizing tumors, and TC-1 cells, which induce non-metastasizing tumors were…”
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Chemotherapy and immunotherapy of tumours induced by gene-modified HPV16-transformed cells by Sobotková, Eva, Dusková, Martina, Smahel, Michal, Holán, Vladimir, Janousková, Olga, Vonka, Vladimir

“…HPV16 E6/E7 transformed mouse kidney cells designated MK16/1/IIIABC (MK16) were modified by the insertion of a suicide gene, viz. the thymidine-kinase gene of…”
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Combined immunization with DNA and transduced tumor cells expressing mouse GM-CSF or IL-2 by Rittich, Simon, Duskova, Martina, Mackova, Jana, Pokorna, Dana, Jinoch, Pavel, Smahel, Michal

“…A combination of different types of vaccines usually induces enhanced immune responses in comparison to immunization with single vaccines. The highest efficacy…”
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DNA vaccines based on chimeric potyvirus-like particles carrying HPV16 E7 peptide (aa 44-60) by Pokorna, Dana, Cerovska, Noemi, Smahel, Michal, Moravec, Tomas, Ludvikova, Viera, Mackova, Jana, Synkova, Helena, Duskova, Martina, Hozak, Pavel, Veleminsky, Jiri

“…Vaccine strategies for the treatment of human papillomavirus-induced cervical cancer are based mainly on the human papillomavirus 16 E7 (HPV16 E7) oncoprotein…”
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