Search Results - "DURAND, C"
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Overcoming barriers and stigma: new frontiers in solid organ transplantation for people with HIV
Published in Clinical microbiology reviews (14-03-2024)“…There is a growing need for solid organ transplantation (SOT) for people living with human immunodeficiency virus (HIV). With the advent of antiretroviral…”
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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
Published in Nature genetics (01-12-2019)“…Enhancer elements in the human genome control how genes are expressed in specific cell types and harbor thousands of genetic variants that influence risk for…”
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SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism
Published in Molecular psychiatry (01-01-2012)“…Genetic mutations of SHANK3 have been reported in patients with intellectual disability, autism spectrum disorder (ASD) and schizophrenia. At the synapse,…”
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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
Published in Proceedings of the National Academy of Sciences - PNAS (24-11-2015)“…We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these maps with new Hi-C, microscopy, and…”
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Nociceptin/orphanin FQ peptide receptor antagonist JTC‐801 reverses pain and anxiety symptoms in a rat model of post‐traumatic stress disorder
Published in British journal of pharmacology (01-01-2015)“…Background and Purpose Single‐prolonged stress (SPS), a rat model of post‐traumatic stress disorder (PTSD), also induces long‐lasting hyperalgesia associated…”
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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Published in Cell (18-12-2014)“…We use in situ Hi-C to probe the 3D architecture of genomes, constructing haploid and diploid maps of nine cell types. The densest, in human lymphoblastoid…”
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systematic review of built environment factors related to physical activity and obesity risk: implications for smart growth urban planning
Published in Obesity reviews (01-05-2011)“…Smart growth is an approach to urban planning that provides a framework for making community development decisions. Despite its growing use, it is not known…”
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The Energetics and Physiological Impact of Cohesin Extrusion
Published in Cell (17-05-2018)“…Cohesin extrusion is thought to play a central role in establishing the architecture of mammalian genomes. However, extrusion has not been visualized in vivo,…”
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Integrated Photonic Platform Based on InGaN/GaN Nanowire Emitters and Detectors
Published in Nano letters (11-06-2014)“…We report the fabrication of a photonic platform consisting of single wire light-emitting diodes (LED) and photodetectors optically coupled by waveguides…”
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Transdiagnostic cognitive-behavioral group therapy for anxiety disorders: Therapists’ perception of group management in community-based care
Published in European psychiatry (01-06-2022)“…Introduction Cognitive-behavioral therapy (CBT) is recognized as an effective treatment for anxiety disorders. Transdiagnostic group CBT (tCBT) targets…”
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CTCF looping is established during gastrulation in medaka embryos
Published in Genome research (01-06-2021)“…Chromatin looping plays an important role in genome regulation. However, because ChIP-seq and loop-resolution Hi-C (DNA-DNA proximity ligation) are extremely…”
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Chromatin architecture transitions from zebrafish sperm through early embryogenesis
Published in Genome research (01-06-2021)“…Chromatin architecture mapping in 3D formats has increased our understanding of how regulatory sequences and gene expression are connected and regulated in a…”
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Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase Sensing in Human Hepatocytes
Published in Hepatology (Baltimore, Md.) (01-11-2018)“…Chronic hepatitis B virus (HBV) infection is a major cause of chronic liver disease and cancer worldwide. The mechanisms of viral genome sensing and the…”
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The impact of direct‐acting antiviral agents on liver and kidney transplant costs and outcomes
Published in American journal of transplantation (01-10-2018)“…Direct‐acting antiviral medications (DAAs) have revolutionized care for hepatitis C positive (HCV+) liver (LT) and kidney (KT) transplant recipients…”
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15
Abnormal melatonin synthesis in autism spectrum disorders
Published in Molecular psychiatry (01-01-2008)“…Melatonin is produced in the dark by the pineal gland and is a key regulator of circadian and seasonal rhythms. A low melatonin level has been reported in…”
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Managing magnets: An audit of introduction of the Royal College of Emergency Medicine Best Practice Guideline
Published in Acta Paediatrica (01-01-2024)“…Aim To evaluate management of children and young people presenting to the Emergency Department (ED) with magnet ingestion before and after new guidance…”
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Mechanical behavior of CAD/CAM occlusal ceramic reconstruction assessed by digital color holography
Published in Dental materials (01-08-2018)“…[Display omitted] •3D holography is used for the first time on a half cut reconstructed tooth.•Mechanical behavior is investigated on a occlusal veneer under…”
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A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses
Published in Hepatology (Baltimore, Md.) (01-01-2016)“…Chronic hepatitis B and D infections are major causes of liver disease and hepatocellular carcinoma worldwide. Efficient therapeutic approaches for cure are…”
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The Energetics and Physiological Impact of Cohesin Extrusion
Published in Cell (20-09-2018)Get full text
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Early development of the neural plate: New roles for apoptosis and for one of its main effectors caspase-3
Published in Genesis (New York, N.Y. : 2000) (01-02-2015)“…Summary Despite its tremendous complexity, the vertebrate nervous system emerges from a homogenous layer of neuroepithelial cells, the neural plate. Its…”
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