Search Results - "DUNSDON, R. M"

The identification of α-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase by BENNETT, J. M, CAMPBELL, A. D, KAY, P. B, O'BRIEN, M. A, KING-UNDERWOOD, J, RAYNHAM, T. M, WILKINSON, C. S, WILKINSON, T. C. I, WILSON, F. X, CAMPBELL, A. J, CARR, M. G, DUNSDON, R. M, GREENING, J. R, HURST, D. N, JENNINGS, N. S, JONES, P. S, JORDAN, S

“…Peptides based upon the non-prime side residues of the NS4A-4B cleavage site of hepatitis C virus (HCV) NS3-4A proteinase containing an alpha-ketoamide moiety…”
Get full text

Solid phase synthesis of aminoboronic acids: potent inhibitors of the hepatitis C virus NS3 proteinase by Dunsdon, Rachel M, Greening, John R, Jones, Philip S, Jordan, Steven, Wilson, Francis X

“…Use of a resin bound diol as a boronic acid protecting group has been developed to allow the parallel synthesis of potent inhibitors of the hepatitis C virus…”
Get full text

The Design and Synthesis of Potent Inhibitors of Hepatitis C Virus NS3–4A Proteinase by Attwood, MR, Bennett, JM, Campbell, AD, Canning, GGM, Carr, MG, Conway, E, Dunsdon, RM, Greening, JR, Jones, PS, Kay, PB, Handa, BK, Hurst, DN, Jennings, NS, Jordan, S, Keech, E, O'Brien, MA, Overton, HA, King-Underwood, J, Raynham, TM, Stenson, KP, Wilkinson, CS, Wilkinson, TCI, Wilson, FX

“…Hepatitis C virus (HCV) is the cause of the majority of transfusion-associated hepatitis and a significant proportion of community-acquired hepatitis…”
Get full text

Peptide based inhibitors of interleukin-8: structural simplification and enhanced potency by Attwood, Michael R., Conway, Elizabeth A., Dunsdon, Rachel M., Greening, John R., Handa, Balraj K., Jones, Philip S., Jordan, Steven C., Keech, Elizabeth, Wilson, Francis X.

“…Important areas of a lead peptide inhibitor of IL-8 had been previously identified. Chemical modification led to the identification of key amide bonds which…”
Get full text

Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity by Guertin, Kevin R., Setti, Lina, Qi, Lida, Dunsdon, Rachel M., Dymock, Brian W., Jones, Philip S., Overton, Hilary, Taylor, Mathew, Williams, Glyn, Sergi, Joseph A., Wang, Karen, Peng, Ying, Renzetti, Marcia, Boyce, Rogely, Falcioni, Fiorenza, Garippa, Ralph, Olivier, Andrée R.

“…A novel series of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents have been identified. These compounds show non-selective…”
Get full text