Search Results - "DUNGEY, A. A"

Replication-Dependent Radiosensitization of Human Glioma Cells by Inhibition of Poly(ADP-Ribose) Polymerase: Mechanisms and Therapeutic Potential by Dungey, Fiona A., B.Sc, Löser, Dana A., M.Sc, Chalmers, Anthony J., F.R.C.R., Ph.D

“…Purpose Current treatments for glioblastoma multiforme are inadequate and limited by the radiation sensitivity of normal brain. Because glioblastoma multiforme…”
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Quantitative analysis of glycoconjugate precursors of guaiacol in smoke-affected grapes using liquid chromatography–tandem mass spectrometry based stable isotope dilution analysis by Dungey, Kerry A., Hayasaka, Yoji, Wilkinson, Kerry L.

“…► A method for quantifying guaiacol glycoconjugates has been developed and validated. ► Glycoconjugates accumulated in grape berries following grapevine…”
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Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90 by Dungey, Fiona A, Caldecott, Keith W, Chalmers, Anthony J

“…Glioblastoma multiforme (GBM) are the most common primary brain tumor and are resistant to standard therapies. The nondividing nature of normal brain provides…”
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Anti-trypanosomal activities of DNA topoisomerase inhibitors by Deterding, Alexander, Dungey, Fiona A., Thompson, Katy-Anne, Steverding, Dietmar

“…Only four drugs are available for chemotherapy of human African sleeping sickness with undesirable toxic side effects. The development of new anti-trypanosomal…”
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Cotransfection of heme oxygenase-1 prevents the acute inflammation elicited by a second adenovirus by MCCARTER, S. D, SCOTT, J. R, POTTER, R. F, LEE, P. J, ZHANG, X, CHOI, A. M. K, MCLEAN, C. A, BADHWAR, A, DUNGEY, A. A, BIHARI, A, HARRIS, K. A

“…The acute inflammatory response elicited by adenovirus vectors results in loss of gene expression and tissue injury in the target organ. This acute…”
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Endogenous heme oxygenase induction is a critical mechanism attenuating apoptosis and restoring microvascular perfusion following limb ischemia/reperfusion by McCarter, Sarah D., Akyea, Thelma G., Lu, Xiangru, Bihari, Aurelia, Scott, Jeffrey R., Badhwar, Amit, Dungey, Alison A., Harris, Kenneth A., Feng, Qingping, Potter, Richard F.

“…A protective role for endogenous heme oxygenase (HO) in the initiation of remote liver injury after limb ischemia/reperfusion has been established. This study…”
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Identification of a β- d-glucopyranoside precursor to guaiacol in grape juice following grapevine exposure to smoke by Hayasaka, Y., Dungey, K.A., Baldock, G.A., Kennison, K.R., Wilkinson, K.L.

“…The presence of the β- d-glucopyranoside of guaiacol (glucoside) in juice of grapes following grapevine exposure to smoke was investigated. The glucoside was…”
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Protective mechanisms during ischemic tolerance in skeletal muscle by Badhwar, Amit, Bihari, Aurelia, Dungey, Alison A, Scott, Jeffrey R, Albion, Caroline D, Forbes, Thomas L, Harris, Kenneth A, Potter, Richard F

“…The purpose of this study was to test specific mechanisms of protection afforded the rat extensor digitorum longus (EDL) muscle during ischemic tolerance. Two…”
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Role of Heme Oxygenase in the Protection Afforded Skeletal Muscle During Ischemic Tolerance by DUNGEY, ALISON A., BADHWAR, AMIT, BIHARI, AURELIA, KVIETYS, PETER R., HARRIS, KENNETH A., FORBES, THOMAS L., POTTER, RICHARD F.

“…Objective: Ischemic tolerance (IT) is known to improve resistance to ischemia/reperfusion (I/R)-induced injury; however, the mechanisms remain unknown. The…”
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Remote Liver Injury is Attenuated by Adenovirus-Mediated Gene Transfer of Heme Oxygenase-1 During the Systemic Inflammatory Response Syndrome by MCCARTER, SARAH D., BADHWAR, AMIT, SCOTT, JEFFREY R., AKYEA, THELMA G., BIHARI, AURELIA, DUNGEY, ALISON A., HARRIS, KENNETH A., POTTER, RICHARD F.

“…Objectives: Adenovirus-mediated gene therapy is being investigated with increasing success for future treatment of autoimmune diseases. However, the use of…”
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Limitations of Ischemic Tolerance in Oxidative Skeletal Muscle: Perfusion vs Tissue Protection by Badhwar, Amit, Dungey, Alison A, Harris, Kenneth A, Scott, Jeremy A, McCarter, Sarah D, Scott, Jeffery R, Forbes, Thomas L, Potter, Richard F

“…Objective. This study determined if ischemic tolerance occurs in oxidative skeletal muscle following a severe ischemia/reperfusion (I/R) insult and if such…”
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Chronic lower extremity ischemia: a human model of ischemic tolerance by Badhwar, Amit, Forbes, Thomas L, Lovell, Marge B, Dungey, Alison A, McCarter, Sarah D, Scott, Jeffrey R, DeRose, Guy, Harris, Kenneth A, Potter, Richard F

“…Ischemic preconditioning (IPC) has been found in animals to have a protective effect against future ischemic injury to muscle tissue. Such injury is…”
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Identification of a b-d-glucopyranoside precursor to guaiacol in grape juice following grapevine exposure to smoke by Hayasaka, Y, Dungey, KA, Baldock, G A, Kennison, K R, Wilkinson, K L

“…The presence of the b-d-glucopyranoside of guaiacol (glucoside) in juice of grapes following grapevine exposure to smoke was investigated. The glucoside was…”
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Abstract 17982: Krìppel-Like Transcription Factor- 2 Preserves Endothelial Function and Protects Against Pulmonary Hypertension by Dungey, Alison A, Deng, Yupu, Yin, Jun, Rozowsky, Simon, Stewart, Duncan J

“…Abstract only RATIONALE: Pulmonary Hypertension (PH) is associated with ongoing endothelial cell (EC) dysfunction. Shear-responsive Krüppel-like Transcription…”
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Enhanced radiosensitisation of human glioma cells by combining inhibition of PARP with inhibition of Hsp90 by Dungey, Fiona A, Caldecott, Keith W, Chalmers, Anthony J

“…Glioblastoma multiforme are the commonest primary brain tumour and are resistant to standard therapies. The non-dividing nature of normal brain provides an…”
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DNA topoisomerase inhibitors as anti-trypanosomal drugs by Steverding, D, Deterding, A, Dungey, F A, K-A, Thompson

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Identification of a β3-D-glucopyranoside precursor to guaiacol in grape juice following grapevine exposure to smoke by HAYASAKA, Y, DUNGEY, K. A, BALDOCK, G. A, KENNISON, K. R, WILKINSON, K. L

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Targeting replication-specific dna repair pathways to enhance the therapeutic ratio of brain tumour radiotherapy by Dungey, Fiona A

“…Glioblastoma multiforme is associated with poor prognosis and resistance to standard therapy. However the non-dividing nature of normal brain provides an…”
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