Search Results - "DUNCKER, C"

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement by Kalinski, Ashley L, Yoon, Choya, Huffman, Lucas D, Duncker, Patrick C, Kohen, Rafi, Passino, Ryan, Hafner, Hannah, Johnson, Craig, Kawaguchi, Riki, Carbajal, Kevin S, Jara, Juan Sebastian, Hollis, Edmund, Geschwind, Daniel H, Segal, Benjamin M, Giger, Roman J

“…Sciatic nerve crush injury triggers sterile inflammation within the distal nerve and axotomized dorsal root ganglia (DRGs). Granulocytes and pro-inflammatory…”
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An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE by Stoolman, Joshua S, Duncker, Patrick C, Huber, Amanda K, Giles, David A, Washnock-Schmid, Jesse M, Soulika, Athena M, Segal, Benjamin M

“…Myelin oligodendrocyte glycoprotein (MOG)-reactive T-helper (Th)1 cells induce conventional experimental autoimmune encephalomyelitis (cEAE), characterized by…”
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Striatal dopamine D1 and D2 receptors: Widespread influences on methamphetamine-induced dopamine and serotonin neurotoxicity by Gross, Noah B., Duncker, Patrick C., Marshall, John F.

“…Methamphetamine (mAMPH) is an addictive psychostimulant drug that releases monoamines through nonexocytotic mechanisms. In animals, binge mAMPH dosing regimens…”
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Cortical ionotropic glutamate receptor antagonism protects against methamphetamine-induced striatal neurotoxicity by Gross, N.B, Duncker, P.C, Marshall, J.F

“…Abstract Binge administration of the psychostimulant drug, methamphetamine (mAMPH), produces long-lasting structural and functional abnormalities in the…”
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Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors by Duncker, Swantje C, Philippe, David, Martin-Paschoud, Christine, Moser, Mireille, Mercenier, Annick, Nutten, Sophie

“…The incidence of food hypersensitivity and food allergies is on the rise and new treatment approaches are needed. We investigated whether N. sativa, one of its…”
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The d‐alanine content of lipoteichoic acid is crucial for Lactobacillus plantarum‐mediated protection from visceral pain perception in a rat colorectal distension model by Duncker, S. C., Wang, L., Hols, P., Bienenstock, J.

“…The mechanisms leading to positive effects of probiotics in irritable bowel syndrome and inflammatory bowel disease have not been clarified, but the possible…”
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CNS-resident classical DCs play a critical role in CNS autoimmune disease by Giles, David A, Duncker, Patrick C, Wilkinson, Nicole M, Washnock-Schmid, Jesse M, Segal, Benjamin M

“…Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system (CNS), induced by the adoptive transfer…”
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Quantifying the impact of PFOA exposure on B-cell development and antibody production by Taylor, Krystal D, Woodlief, Tracey L, Ahmed, Aya, Hu, Qing, Duncker, Patrick C, DeWitt, Jamie C

“…Abstract Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals; the vast majority are environmentally and biologically persistent, and some have…”
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GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction by Duncker, Patrick C, Stoolman, Joshua S, Huber, Amanda K, Segal, Benjamin M

“…GM-CSF has been portrayed as a critical cytokine in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and, ostensibly, in multiple sclerosis…”
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Myeloid cell plasticity in the evolution of central nervous system autoimmunity by Giles, David A., Washnock‐Schmid, Jesse M., Duncker, Patrick C., Dahlawi, Somiah, Ponath, Gerald, Pitt, David, Segal, Benjamin M.

“…Objective Myeloid cells, including macrophages and dendritic cells, are a prominent component of central nervous system (CNS) infiltrates during multiple…”
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Effect of orally administered probiotic E. coli strain Nissle 1917 on intestinal mucosal immune cells of healthy young pigs by Duncker, Swantje C., Lorentz, Axel, Schroeder, Bernd, Breves, Gerhard, Bischoff, Stephan C.

“…Several beneficial effects of probiotics have been described in studies using rodent disease models and in human patients; however, the underlying mechanisms…”
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Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children by Xu, Qin, Milanez-Almeida, Pedro, Martins, Andrew J., Radtke, Andrea J., Hoehn, Kenneth B., Oguz, Cihan, Chen, Jinguo, Liu, Can, Tang, Juanjie, Grubbs, Gabrielle, Stein, Sydney, Ramelli, Sabrina, Kabat, Juraj, Behzadpour, Hengameh, Karkanitsa, Maria, Spathies, Jacquelyn, Kalish, Heather, Kardava, Lela, Kirby, Martha, Cheung, Foo, Preite, Silvia, Duncker, Patrick C., Kitakule, Moses M., Romero, Nahir, Preciado, Diego, Gitman, Lyuba, Koroleva, Galina, Smith, Grace, Shaffer, Arthur, McBain, Ian T., McGuire, Peter J., Pittaluga, Stefania, Germain, Ronald N., Apps, Richard, Schwartz, Daniella M., Sadtler, Kaitlyn, Moir, Susan, Chertow, Daniel S., Kleinstein, Steven H., Khurana, Surender, Tsang, John S., Mudd, Pamela, Schwartzberg, Pamela L., Manthiram, Kalpana

“…Most studies of adaptive immunity to SARS-CoV-2 infection focus on peripheral blood, which may not fully reflect immune responses at the site of infection…”
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Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis by Stoolman, Joshua S, Duncker, Patrick C, Huber, Amanda K, Segal, Benjamin M

“…The adoptive transfer of myelin-reactive T cells into wild-type hosts results in spinal cord inflammation and ascending paralysis, referred to as conventional…”
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Neutrophils promote VLA-4–dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation by Harp, Chelsea R. Parker, Archambault, Angela S., Cheung, Matthew, Williams, Jesse W., Czepielewski, Rafael S., Duncker, Patrick C., Kilgore, Aaron J., Miller, Aidan T., Segal, Benjamin M., Kim, Alfred H. J., Randolph, Gwendalyn J., Wu, Gregory F.

“…The success of B cell depletion therapies and identification of leptomeningeal ectopic lymphoid tissue (ELT) in patients with multiple sclerosis (MS) has…”
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CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells by HALE, G, JACOBS, P, DUNCKER, C, WIESNETH, M, SELLESLAG, D, HIDAJAT, M, STAROBINSKI, M, BIRD, P, WALDMANN, H, WOOD, L, FIBBE, W. E, BARGE, R, NOVITZKY, N, TOIT, C. D, ABRAHAMS, L, THOMAS, V, BUNJES, D

“…Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity after allogeneic bone marrow transplantation, but can be avoided by removing T…”
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Immune responses to non-tumor antigens in the central nervous system by Huber, Amanda K, Duncker, Patrick C, Irani, David N

“…The central nervous system (CNS), once viewed as an immune-privileged site protected by the blood-brain barrier (BBB), is now known to be a dynamic…”
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Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models by Parker, Scott, McDowall, Charlotte, Sanchez-Perez, Luis, Osorio, Cristina, Duncker, Patrick C, Briley, Aaron, Swartz, Adam M, Herndon, 2nd, James E, Yu, Yen-Rei A, McLendon, Roger E, Tedder, Thomas F, Desjardins, Annick, Ashley, David M, Gunn, Michael Dee, Enterline, David S, Knorr, David A, Pastan, Ira H, Nair, Smita K, Bigner, Darell D, Chandramohan, Vidyalakshmi

“…D2C7-immunotoxin (IT), a dual-specific IT targeting wild-type epidermal growth factor receptor (EGFR) and mutant EGFR variant III (EGFRvIII) proteins,…”
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The conundrum of interferon-β non-responsiveness in relapsing–remitting multiple sclerosis by Huber, Amanda K., Duncker, Patrick C., Irani, David N.

“…A series of controlled clinical trials have shown that exogenous interferon-beta (IFN-β) benefits patients with relapsing–remitting multiple sclerosis (RRMS)…”
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Probiotic Lactobacillus reuteri alleviates the response to gastric distension in rats by Duncker, Swantje C, Kamiya, Takeshi, Wang, Lu, Yang, Pingchang, Bienenstock, John

“…Probiotic lactic acid bacteria have been reported to alleviate symptoms in patients with irritable bowel syndrome. However, they have not been tested for use…”
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Non-infectious lung complications are closely associated with chronic graft-versus-host disease : a single center study of incidence, risk factors and outcome by DUNCKER, C, DOHR, D, HEIMPEL, H, BERGMANN, L, BUNJES, D, VON HARSDORF, S, DUYSTER, J, STEFANIC, M, MARTINI, C, TREIBER, M, HERTENSTEIN, B, NOVOTNY, J, ARNOLD, R

“…Non-infectious lung complications (NILC) are frequent, influencing morbidity and mortality of patients after allogeneic BMT. Although the term NILC encompasses…”
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