Search Results - "DUNCAN, Lyn M"

Resistance to checkpoint blockade therapy through inactivation of antigen presentation by Sade-Feldman, Moshe, Jiao, Yunxin J., Chen, Jonathan H., Rooney, Michael S., Barzily-Rokni, Michal, Eliane, Jean-Pierre, Bjorgaard, Stacey L., Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Frederick, Dennie T., Hazar-Rethinam, Mehlika, Nadres, Brandon A., Van Seventer, Emily E., Shukla, Sachet A., Yizhak, Keren, Ray, John P., Rosebrock, Daniel, Livitz, Dimitri, Adalsteinsson, Viktor, Getz, Gad, Duncan, Lyn M., Li, Bo, Corcoran, Ryan B., Lawrence, Donald P., Stemmer-Rachamimov, Anat, Boland, Genevieve M., Landau, Dan A., Flaherty, Keith T., Sullivan, Ryan J., Hacohen, Nir

“…Treatment with immune checkpoint blockade (CPB) therapies often leads to prolonged responses in patients with metastatic melanoma, but the common mechanisms of…”
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Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma by Lian, Christine Guo, Xu, Yufei, Ceol, Craig, Wu, Feizhen, Larson, Allison, Dresser, Karen, Xu, Wenqi, Tan, Li, Hu, Yeguang, Zhan, Qian, Lee, Chung-wei, Hu, Di, Lian, Bill Q., Kleffel, Sonja, Yang, Yijun, Neiswender, James, Khorasani, Abraham J., Fang, Rui, Lezcano, Cecilia, Duncan, Lyn M., Scolyer, Richard A., Thompson, John F., Kakavand, Hojabr, Houvras, Yariv, Zon, Leonard I., Mihm, Martin C., Kaiser, Ursula B., Schatton, Tobias, Woda, Bruce A., Murphy, George F., Shi, Yujiang G.

“…DNA methylation at the 5 position of cytosine (5-mC) is a key epigenetic mark that is critical for various biological and pathological processes. 5-mC can be…”
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Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families by Njauw, Ching-Ni Jenny, Kim, Ivana, Piris, Adriano, Gabree, Michele, Taylor, Michael, Lane, Anne Marie, DeAngelis, Margaret M, Gragoudas, Evangelos, Duncan, Lyn M, Tsao, Hensin

“…BAP1 has been shown to be a target of both somatic alteration in high-risk ocular melanomas (OM) and germline inactivation in a few individuals from…”
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Identification of cells initiating human melanomas by Frank, Markus H, Schatton, Tobias, Murphy, George F, Frank, Natasha Y, Yamaura, Kazuhiro, Waaga-Gasser, Ana Maria, Gasser, Martin, Zhan, Qian, Jordan, Stefan, Duncan, Lyn M, Weishaupt, Carsten, Fuhlbrigge, Robert C, Kupper, Thomas S, Sayegh, Mohamed H

“…Tumour-initiating cells capable of self-renewal and differentiation, which are responsible for tumour growth, have been identified in human haematological…”
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Importance of glycolysis and oxidative phosphorylation in advanced melanoma by Ho, Jonhan, de Moura, Michelle Barbi, Lin, Yan, Vincent, Garret, Thorne, Stephen, Duncan, Lyn M, Hui-Min, Lin, Kirkwood, John M, Becker, Dorothea, Van Houten, Bennett, Moschos, Stergios J

“…Serum lactate dehydrogenase (LDH) is a prognostic factor for patients with stage IV melanoma. To gain insights into the biology underlying this prognostic…”
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MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth by Nemlich, Yael, Greenberg, Eyal, Ortenberg, Rona, Besser, Michal J, Barshack, Iris, Jacob-Hirsch, Jasmine, Jacoby, Elad, Eyal, Eran, Rivkin, Ludmila, Prieto, Victor G, Chakravarti, Nitin, Duncan, Lyn M, Kallenberg, David M, Galun, Eitan, Bennett, Dorothy C, Amariglio, Ninette, Bar-Eli, Menashe, Schachter, Jacob, Rechavi, Gideon, Markel, Gal

“…Some solid tumors have reduced posttranscriptional RNA editing by adenosine deaminase acting on RNA (ADAR) enzymes, but the functional significance of this…”
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Integrative genome comparison of primary and metastatic melanomas by Kabbarah, Omar, Nogueira, Cristina, Feng, Bin, Nazarian, Rosalynn M, Bosenberg, Marcus, Wu, Min, Scott, Kenneth L, Kwong, Lawrence N, Xiao, Yonghong, Cordon-Cardo, Carlos, Granter, Scott R, Ramaswamy, Sridhar, Golub, Todd, Duncan, Lyn M, Wagner, Stephan N, Brennan, Cameron, Chin, Lynda

“…A cardinal feature of malignant melanoma is its metastatic propensity. An incomplete view of the genetic events driving metastatic progression has been a major…”
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Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma by Qin, Yong, Ekmekcioglu, Suhendan, Liu, Ping, Duncan, Lyn M, Lizée, Gregory, Poindexter, Nancy, Grimm, Elizabeth A

“…Interleukin (IL)-1-mediated inflammation is proposed to contribute to the development and progression of some cancers. IL-1 family member proteins are known to…”
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MERTK receptor tyrosine kinase is a therapeutic target in melanoma by Schlegel, Jennifer, Sambade, Maria J, Sather, Susan, Moschos, Stergios J, Tan, Aik-Choon, Winges, Amanda, DeRyckere, Deborah, Carson, Craig C, Trembath, Dimitri G, Tentler, John J, Eckhardt, S Gail, Kuan, Pei-Fen, Hamilton, Ronald L, Duncan, Lyn M, Miller, C Ryan, Nikolaishvili-Feinberg, Nana, Midkiff, Bentley R, Liu, Jing, Zhang, Weihe, Yang, Chao, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Shields, Janiel M, Graham, Douglas K

“…Metastatic melanoma is one of the most aggressive forms of cutaneous cancers. Although recent therapeutic advances have prolonged patient survival, the…”
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Outcome of patients with de novo versus nevus-associated melanoma by Lin, William M., MD, Luo, Su, MD, Muzikansky, Alona, MA, Lobo, Alice Z.C., MD, Tanabe, Kenneth K., MD, Sober, Arthur J., MD, Cosimi, A. Benedict, MD, Tsao, Hensin, MD, PhD, Duncan, Lyn M., MD

“…Background Prior reports indicate a wide range of melanomas in histopathologic contiguity with a nevus, and an associated nevus has unclear prognostic…”
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Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene by Kim, Minjung, Gans, Joseph D., Nogueira, Cristina, Wang, Audrey, Paik, Ji-Hye, Feng, Bin, Brennan, Cameron, Hahn, William C., Cordon-Cardo, Carlos, Wagner, Stephan N., Flotte, Thomas J., Duncan, Lyn M., Granter, Scott R., Chin, Lynda

“…Genomes of human cancer cells are characterized by numerous chromosomal aberrations of uncertain pathogenetic significance. Here, in an inducible mouse model…”
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Subcutaneous Sweet syndrome in the setting of myeloid disorders: A case series and review of the literature by Chan, May P., MD, Duncan, Lyn M., MD, Nazarian, Rosalynn M., MD

“…Background The association of neutrophilic dermatoses with myeloid disorders is well known, but neutrophilic panniculitis in the same setting has only been…”
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IgG4 Expression in Primary Cutaneous Marginal Zone Lymphoma: A Multicenter Study by De Souza, Aieska, Ferry, Judith A, Burghart, Daniel R, Tinguely, Marianne, Goyal, Amrita, Duncan, Lyn M, Kutzner, Heinz, Kempf, Werner

“…Primary cutaneous marginal zone lymphoma (PCMZL) is the second most common B-cell lymphoma of the skin. A recent study has demonstrated a strikingly high…”
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Warfarin-induced skin necrosis by Nazarian, Rosalynn M., MD, Van Cott, Elizabeth M., MD, Zembowicz, Artur, MD, PhD, Duncan, Lyn M., MD

“…Warfarin-induced skin necrosis is a rare complication of anticoagulant therapy with a high associated morbidity and mortality requiring immediate drug…”
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Increased diagnosis of thin superficial spreading melanomas: A 20-year study by Frangos, Jason E., MD, Duncan, Lyn M., MD, Piris, Adriano, MD, Nazarian, Rosalynn M., MD, Mihm, Martin C., MD, Hoang, Mai P., MD, Gleason, Briana, MD, Flotte, Thomas J., MD, Byers, Hugh R., MD, Barnhill, Raymond L., MD, Kimball, Alexa B., MD, MPH

“…Background Diagnostic practice by dermatopathologists evaluating pigmented lesions may have evolved over time. Objectives We sought to investigate diagnostic…”
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Congenital melanocytic nevi: Clinical and histopathologic features, risk of melanoma, and clinical management by Tannous, Zeina S., Mihm, Martin C., Sober, Arthur J., Duncan, Lyn M.

“…Congenital melanocytic nevi occur in approximately 1% of newborns and are usually classified according to their size. Giant congenital melanocytic nevi are…”
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Wolf isotopic response manifesting as postherpetic granuloma annulare: a case series by Kapoor, Roger, Piris, Adriano, Saavedra, Arturo P, Duncan, Lyn M, Nazarian, Rosalynn M

“…Wolf isotopic response has infrequently been reported in the literature, mainly as isolated case reports. To aid in recognition of the occurrence of…”
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Sentinel lymph node metastasis is not predictive of poor outcome in patients with problematic spitzoid melanocytic tumors by Hung, Tawny, MD, Piris, Adriano, MD, Lobo, Alice, MD, Mihm, Martin C., MD, Sober, Arthur J., MD, Tsao, Hensin, MD, Tanabe, Kenneth K., MD, Duncan, Lyn M., MD

“…Summary The diagnosis and clinical management of spitzoid melanocytic tumors with atypical features remain problematic and controversial. In the past decade,…”
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Delivering value in dermatology: Insights from skin cancer detection in routine clinical visits by Enamandram, Monica, MD, Duncan, Lyn M., MD, Kimball, Alexandra B., MD, MPH

“…Background There are increasing demands to demonstrate and report on outcomes in dermatology. Skin cancer diagnosis through skin examination has been well…”
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Interinstitutional whole slide imaging teleconsultation service development: assessment using internal training and clinical consultation cases by Jones, Nicholas C, Nazarian, Rosalynn M, Duncan, Lyn M, Kamionek, Michal, Lauwers, Gregory Y, Tambouret, Rosemary H, Wu, Chin-Lee, Nielsen, G Petur, Brachtel, Elena F, Mark, Eugene J, Sadow, Peter M, Grabbe, John P, Wilbur, David C

“…Assessment of accuracy and feasibility of whole slide imaging (WSI) for interinstitutional consultation in surgical pathology. To train technical and…”
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