Search Results - "DUFOUR, Jason"
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Long-primed germinal centres with enduring affinity maturation and clonal migration
Published in Nature (London) (29-09-2022)“…Germinal centres are the engines of antibody evolution. Here, using human immunodeficiency virus (HIV) Env protein immunogen priming in rhesus monkeys followed…”
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2
Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue
Published in Journal of cellular biochemistry (01-12-2006)“…The biologic characteristics of mesenchymal stem cells (MSCs) isolated from two distinct tissues, bone marrow and adipose tissue were evaluated in these…”
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3
Long-term in vitro expansion alters the biology of adult mesenchymal stem cells
Published in Cancer research (Chicago, Ill.) (01-06-2008)“…Mesenchymal stem cells (MSC) derived from bone marrow stem cells (BMSC) and adipose tissue stem cells (ASC) of humans and rhesus macaques were evaluated for…”
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4
Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long‐term non‐progressing Chinese rhesus macaques
Published in Journal of medical virology (01-01-2023)“…The gut is a major reservoir in HIV‐infected individuals on antiretroviral therapy (ART) and in long‐term non‐progressors (LTNPs). Whether ART reduces gut…”
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5
Chronic binge alcohol and ovariectomy-mediated impaired insulin responsiveness in SIV-infected female rhesus macaques
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-11-2021)“…Aging people living with HIV (PLWH), especially postmenopausal women may be at higher risk of comorbidities associated with HIV, antiretroviral therapy (ART),…”
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Non-human primate model of long-COVID identifies immune associates of hyperglycemia
Published in Nature communications (20-08-2024)“…Hyperglycemia, and exacerbation of pre-existing deficits in glucose metabolism, are manifestations of the post-acute sequelae of SARS-CoV-2. Our understanding…”
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7
Neuroinflammatory Profiling in SIV-Infected Chinese-Origin Rhesus Macaques on Antiretroviral Therapy
Published in Viruses (13-01-2022)“…The central nervous system (CNS) HIV reservoir is an obstacle to achieving an HIV cure. The basal ganglia harbor a higher frequency of SIV than other brain…”
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8
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge
Published in Cell reports (Cambridge) (12-05-2020)“…We compare immunogenicity and protective efficacy of an HIV vaccine comprised of env and gag DNA and Env (Envelope) proteins by co-administration of the…”
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9
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe‐affected non‐human primates by intracerebral lentiviral gene therapy
Published in EMBO molecular medicine (01-05-2016)“…Metachromatic leukodystrophy (MLD) and globoid cell leukodystrophy (GLD or Krabbe disease) are severe neurodegenerative lysosomal storage diseases (LSD) caused…”
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10
Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV-1 Entry via the CCR5 Co-Receptor
Published in The Journal of infectious diseases (01-09-2010)“…An effective vaginal microbicide could reduce human immunodeficiency virus type 1 (HIV-1) transmission to women. Among microbicide candidates in clinical…”
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Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration
Published in Nature (London) (23-02-2023)Get full text
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12
Chronic binge alcohol administration impairs glucose-insulin dynamics and decreases adiponectin in asymptomatic simian immunodeficiency virus-infected macaques
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-11-2016)“…Alcohol use disorders (AUDs) frequently exist among persons living with HIV/AIDS. Chronic alcohol consumption, HIV infection, and antiretroviral therapy (ART)…”
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The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection
Published in Viruses (01-07-2024)“…The effects of immunodeficiency associated with chronic HIV infection on COVID-19 disease and viral persistence have not been directly addressed in a…”
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Beneficial Effects of Human Anti-Interleukin-15 Antibody in Gluten-Sensitive Rhesus Macaques with Celiac Disease
Published in Frontiers in immunology (11-07-2018)“…Overexpression of interleukin-15 (IL-15) is linked with immunopathology of several autoimmune disorders including celiac disease. Here, we utilized an…”
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15
Comparison of fine-needle aspiration techniques
Published in Journal of medical primatology (01-12-2023)“…Fine-needle aspiration (FNA) has been reported since 1912 beginning with the use of trocars and other specialized instruments that were impractical. Since…”
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Dietary Gluten-Induced Gut Dysbiosis Is Accompanied by Selective Upregulation of microRNAs with Intestinal Tight Junction and Bacteria-Binding Motifs in Rhesus Macaque Model of Celiac Disease
Published in Nutrients (28-10-2016)“…The composition of the gut microbiome reflects the overall health status of the host. In this study, stool samples representing the gut microbiomes from 6…”
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Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2012)“…Vaccination and the application of a vaginal microbicide have traditionally been considered independent methods to prevent the sexual transmission of HIV-1 to…”
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Prevention of Vaginal SHIV Transmission in Rhesus Macaques through Inhibition of CCR5
Published in Science (American Association for the Advancement of Science) (15-10-2004)“…Topical agents, such as microbicides, that can protect against human immunodeficiency virus (HIV) transmission are urgently needed. Using a chimeric…”
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A randomized controlled trial of varenicline and brief behavioral counseling delivered by lay counselors for adolescent vaping cessation: Study protocol
Published in Frontiers in psychiatry (15-03-2023)“…Approximately one-fifth of high-school seniors and college students currently vape nicotine. Adolescents express a desire to quit vaping, and case reports have…”
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Ethanol impairs mucosal immunity against Streptococcus pneumoniae infection by disrupting interleukin 17 gene expression
Published in Infection and immunity (01-05-2015)“…Acute ethanol intoxication suppresses the host immune responses against Streptococcus pneumoniae. As interleukin 17 (IL-17) is a critical cytokine in host…”
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