Search Results - "DUBEAU, L"

Coming into focus: the nonovarian origins of ovarian cancer by Dubeau, L, Drapkin, R

“…The traditional view of epithelial ovarian cancer asserts that all tumor subtypes share a common origin in the ovarian surface epithelium (OSE) DESIGN: A…”
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Essential role of the unfolded protein response regulator GRP78 BiP in protection from neuronal apoptosis by Wang, M, Ye, R, Barron, E, Baumeister, P, Mao, C, Luo, S, Fu, Y, Luo, B, Dubeau, L, Hinton, D R, Lee, A S

“…Neurodegenerative diseases are often associated with dysfunction in protein quality control. The endoplasmic reticulum (ER), a key site for protein synthesis,…”
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Development of a pan-cancer biomarker panel for improved detection of MSI across all cancer types by Bacher, J., Halberg, R., Ward, P., Udho, E., Murphy, K., Uhr, M., Dubeau, L., Pettersson, J., Storts, D., Gallinger, S., Buchanan, D., Jenkins, M., Lindor, N., Eshleman, J.

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Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors by EHRLICH, M, WOODS, C. B, LAIRD, P. W, YU, M. C, DUBEAU, L, YANG, F, CAMPAN, M, WEISENBERGER, D. J, LONG, T. I, YOUN, B, FIALA, E. S

“…How hypermethylation and hypomethylation of different parts of the genome in cancer are related to each other and to DNA methyltransferase (DNMT) gene…”
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BRCA genes: lessons learned from experimental and clinical cancer by MUGGIA, F, SAFRA, T, DUBEAU, L

“…Advances in the study of BRCA1 and BRCA2 gene functions have relied on the development of animal models for seeking to explore further what we have learned…”
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The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome by KUMAR, S. R, MASOOD, R, WEAVER, F. A, SOOD, A. K, GILL, P. S, SPANNUTH, W. A, SINGH, J, SCEHNET, J, KLEIBER, G, JENNINGS, N, DEAVERS, M, KRASNOPEROV, V, DUBEAU, L

“…EphB4 is a member of the largest family of transmembrane receptor tyrosine kinases and plays critical roles in axonal pathfinding and blood vessel maturation…”
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Presence of olfactory receptors in normal and neoplastic (HEY) cells in the female reproductive tract by Mucowski, S.J, Marion, C, Liu, Y, Bendikson, K.A, Stanczyk, F.Z, Dubeau, L

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Visceral adipocyte glucose-regulated protein (GRP) 78 is an independent risk factor for endometrial cancer survival by Matsuo, K, Srivastava, S.A, Tripathi, P.B, Sonoda, L.A, Yang, D.Y, Yoo, E.J, Pfaffenbach, K.T, Dubeau, L, Lee, A.S, Lin, Y.G

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Adiposity and endometrial cancer: The stress of excess by Matsuo, K, Srivastava, S, Tripathi, P, Sonoda, L, Yoo, E, Pfaffenbac, K, Dubeau, L, Lee, A, Lin, Y

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Loss of heterozygosity on chromosomal segments 3p, 6q and 11p in human ovarian carcinomas by Ehlen, T, Dubeau, L

“…The genetic events involved in human ovarian carcinoma development are still largely unknown. We have used DNA recombinant technologies to examine the genome…”
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Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas by YU, J, ROY, D, BROCKMEYER, A. D, DUBEAU, L

“…Cell cultures of ovarian cystadenomas transfected with SV40 large T antigen are not immortal because they invariably reach a phenomenon called crisis, which is…”
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Alterations in DNA methylation are early, but not initial, events in ovarian tumorigenesis by CHENG, P, SCHMUTTE, C, COFER, K. F, FELIX, J. C, YU, M. C, DUBEAU, L

“…We compared global levels of DNA methylation as well as methylation of a specific locus (MyoD1) in ovarian cystadenomas, ovarian tumours of low malignant…”
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Genetic disparity between morphologically benign cysts contiguous to ovarian carcinomas and solitary cystadenomas by Zheng, J, Benedict, W F, Xu, H J, Hu, S X, Kim, T M, Velicescu, M, Wan, M, Cofer, K F, Dubeau, L

“…Ovarian carcinomas occasionally contain large, histologically benign cysts contiguous to the clearly malignant areas (cystadenocarcinomas). The question of…”
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Ovarian tumor development: insights from ovarian embryogenesis by Rodriguez, M, Dubeau, L

“…The study of ovarian embryogenesis can provide important clues about the etiology and development of the different subtypes of ovarian neoplasms. The coelomic…”
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The Cell of Origin of Ovarian Epithelial Tumors and the Ovarian Surface Epithelium Dogma: Does the Emperor Have No Clothes? by Dubeau, Louis

“…The widely favored hypothesis that ovarian epithelial tumors arise from the mesothelial cell layer lining the ovarian surface fails to explain the resemblance…”
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Coming into focus: the nonovarian origins of ovarian cancer: Hereditary breast and ovarian cancers: lessening the burden by DUBEAU, L, DRAPKIN, R

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Potential Role of the Inactivated X Chromosome in Ovarian Epithelial Tumor Development by Cheng, Pui C., Gosewehr, Jim A., Kim, Timothy M., Velicescu, Mihaela, Wan, Minghong, Zheng, Jianping, Felix, Juan C., Cofer, Kenneth F., Luo, Ping, Biela, Barbara H., Godorov, Gary, Dubeau, Louis

“…Background: Ovarian epithelial tumors can be divided into subcategories often regarded as different stages of neoplastic transformation. Cystadenomas belong to…”
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Telomerase Activity in Benign and Malignant Epithelial Ovarian Tumors by Wan, Minghong, Li, Wei-Zhi, Felix, Juan C., Zhao, Yanle, Dubeau, Louis, Duggan, Bridgette D.

“…Background: Ovarian epithelial tumors include benign lesions lacking invasive and metastatic abilities (cystadenomas) in addition to malignant lesions…”
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D28 THE WEB OF OMICS: DNA, RNA, AND PROTEIN MODIFICATIONS: Association Between Dna Methylation In The Axl Gene At Birth And Childhood Respiratory Health by Gao, L, Millstein, J, Siegmund, K, Dubeau, L, Avol, E, Gilliland, F, Breton, C

“…Methods DNA methylation at birth was measured from newborn blood spots using the Illumina HumanMethylation450 array on a subset of 273 children from the…”
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C-myc proto-oncogene amplification detected by polymerase chain reaction in archival human ovarian carcinomas by Schreiber, G, Dubeau, L

“…Polymerase chain reaction (PCR) technology was used to examine the state of amplification of the proto-oncogene c-myc in archival ovarian carcinomas. Sequences…”
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