Search Results - "DSOUZA, NINOSCHKA"

14-LB: Somatostatin Receptor 2 Antagonism Enhances Plasma Glucagon Levels during Insulin-Induced Hypoglycemia in a Rodent Model of Type 2 Diabetes Mellitus by NEJAD-MANSOURI, MEHRAN, ZAREE BAVANI, PARINAZ, AIKEN, JULIAN, DSOUZA, NINOSCHKA C., HOFFMAN, EMILY G., LIGGINS, RICHARD, RIDDELL, MICHAEL

“…Somatostatin Receptor 2 antagonists (SSTR2a) increase glucagon counter-regulation to hypoglycemia in various rodent models of type-1 diabetes mellitus. Here we…”
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1778-LB: Comparing a Somatostatin Receptor 2 Antagonist (SSTR2a) to Exogenous Glucagon (EG) for the Treatment of Severe Insulin-Induced Hypoglycemia by Hoffman, Emily G, Dsouza, Ninoschka, Aleali, Nadia, Nozariasbmarz, Newsha, Fatehi, Samaneh, Shakeri, Dorsa, Chan, Owen, Liggins, Richard, Riddell, Michael C

“…Introduction & Objective: Treatment of severe hypoglycemia (SH) with EG causes hyperglucagonemia, resulting in gastrointestinal distress that limits its…”
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1773-LB: Impact of SSTR2a Treatment in Hypoglycemia in Male (M) and Female (F) Rat Models of Type 2 Diabetes (T2D) by Dsouza, Ninoschka, Aleali, Nadia, Shakeri, Dorsa, Atherley, Sara C, Hoffman, Emily G, Karimi-Chahartash, Sina, Javanbakhsh, Sahel, Chan, Owen, Liggins, Richard, Riddell, Michael C

“…Introduction: A single dose of SSTR2a, ZT-01, reduces hypoglycemia exposure in diabetic rat models. However, the pharmacology of daily dosing in type 2…”
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1774-LB: The Glucagon Stimulating Effect in Hypoglycemia of Somatostatin Receptor 2 Antagonist (SSTR2a) Is Maintained with Repeat Dosing by Dsouza, Ninoschka, Aleali, Nadia, Shakeri, Dorsa, Atherley, Sara C, Hoffman, Emily G, Karimi-Chahartash, Sina, Javanbakhsh, Sahel, Chan, Owen, Liggins, Richard, Riddell, Michael C

“…Introduction: A single dose of SSTR2a, ZT-01, reduces hypoglycemia exposure in diabetic rat models. However, the pharmacology of daily dosing in type 2…”
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133-OR: Somatostatin Receptor Type 2 Antagonism (SSTR2a) Augments Glucagon Counterregulation and Delays Hypoglycemia Onset in Type 2 Diabetic (T2D), Sprague-Dawley Rats by HOFFMAN, EMILY G., DSOUZA, NINOSCHKA, AIKEN, JULIAN, LIGGINS, RICHARD, RIDDELL, MICHAEL

“…Background: SSTR2a rescues glucagon counterregulation in type 1 diabetic rats. Here, we investigated its potential for resisting hypoglycemic onset in…”
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9-LB: Increased Islet Expression of Somatostatin and Glucagon in Male Rats with Insulin-Dependent Type 2 Diabetes by HOFFMAN, EMILY G., ATHERLEY, SARA C., AKBARIAN, NICKY, DSOUZA, NINOSCHKA, LIGGINS, RICHARD, RIDDELL, MICHAEL

“…Background: Pancreatic islet remodelling in type 1 diabetes increases somatostatin (SST) expression, which inhibits glucagon counterregulation to hypoglycemia…”
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32-LB: Interstitial Glucose Levels during Exercise in Persons with and without Type 1 Diabetes by RIDDELL, MICHAEL, LI, ZHAOMIAN, DSOUZA, NINOSCHKA, YEUNG, CHRISTOPHER, KESIBI, DURMALOUK, PATTON, SUSANA R., BECK, ROY, JACOBS, PETER G., CLEMENTS, MARK A., GAL, ROBIN L., DOYLE, FRANCIS J., MARTIN, CORBY K., CALHOUN, PETER, SHERR, JENNIFER, CASTLE, JESSICA R., RICKELS, MICHAEL R.

“…Background: Using continuous glucose monitoring (CGM), we investigated potential sex-related differences in glycemia during exercise in persons living with…”
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