Search Results - "DRUILLENNEC, S"

Cell context reveals a dual role for Maf in oncogenesis by POUPONNOT, C, SII-FELICE, K, HMITOU, I, ROCQUES, N, LECOIN, L, DRUILLENNEC, S, FELDER-SCHMITTBUHL, M.-P, EYCHENE, A

“…Maf b-Zip transcription factors are involved in both terminal differentiation and oncogenesis. To investigate this apparent contradiction, we used two…”
Get full text

The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway by Roumier, T, Vieira, H L A, Castedo, M, Ferri, K F, Boya, P, Andreau, K, Druillennec, S, Joza, N, Penninger, J M, Roques, B, Kroemer, G

“…Previous biochemical studies suggested that HIV-1-encoded Vpr may kill cells through an effect on the adenine nucleotide translocase (ANT), thereby causing…”
Get full text

Target Specificity of Human Immunodeficiency Virus Type 1 NCp7 Requires an Intact Conformation of Its CCHC N-Terminal Zinc Finger by RAMBOARINA, S, DRUILLENNEC, S, MORELLET, N, BOUAZIZ, S, ROQUES, B. P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Interaction between the HIV-1 Protein Vpr and the Adenine Nucleotide Translocator by Sabbah, Emmanuelle N., Druillennec, S., Morellet, N., Bouaziz, S., Kroemer, G., Roques, B.P.

“…The HIV‐1 protein Vpr circulates in the serum of seropositive individuals and in the cerebrospinal fluid of AIDS patients with neurological disorders. Vpr…”
Get full text

A Mimic of HIV-1 Nucleocapsid Protein Impairs Reverse Transcription and Displays Antiviral Activity by Druillennec, S., Dong, C. Z., Escaich, S., Gresh, N., Bousseau, A., Roques, B. P., Fournié-Zaluski, M. C.

“…Combined inhibition of HIV-1 reverse transcriptase and protease has significantly improved the treatment of AIDS. Nevertheless, resistance to these drugs…”
Get full text

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2 by Jacotot, E, Ferri, K F, El Hamel, C, Brenner, C, Druillennec, S, Hoebeke, J, Rustin, P, Métivier, D, Lenoir, C, Geuskens, M, Vieira, H L, Loeffler, M, Belzacq, A S, Briand, J P, Zamzami, N, Edelman, L, Xie, Z H, Reed, J C, Roques, B P, Kroemer, G

“…Viral protein R (Vpr), an apoptogenic accessory protein encoded by HIV-1, induces mitochondrial membrane permeabilization (MMP) via a specific interaction with…”
Get full text

Helical structure determined by NMR of the HIV‐1 (345–392)Gag sequence, surrounding p2: Implications for particle assembly and RNA packaging by Morellet, Nelly, Druillennec, Sabine, Lenoir, Christine, Bouaziz, Serge, Roques, Bernard P.

“…Gag protein oligomerization, an essential step during virus assembly, results in budding of spherical virus particles. This process is critically dependent on…”
Get full text

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore by Jacotot, E, Ravagnan, L, Loeffler, M, Ferri, K F, Vieira, H L, Zamzami, N, Costantini, P, Druillennec, S, Hoebeke, J, Briand, J P, Irinopoulou, T, Daugas, E, Susin, S A, Cointe, D, Xie, Z H, Reed, J C, Roques, B P, Kroemer, G

“…Viral protein R (Vpr) encoded by HIV-1 is a facultative inducer of apoptosis. When added to intact cells or purified mitochondria, micromolar and submicromolar…”
Get full text

Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2 by Jacotot, Etienne, Ferri, Karine F., El Hamel, Chahrazed, Brenner, Catherine, Druillennec, Sabine, Hoebeke, Johan, Rustin, Pierre, Métivier, Didier, Lenoir, Christine, Geuskens, Maurice, Vieira, Helena L.A., Loeffler, Markus, Belzacq, Anne-Sophie, Briand, Jean-Paul, Zamzami, Naoufal, Edelman, Lena, Xie, Zhi Hua, Reed, John C., Roques, Bernard P., Kroemer, Guido

“…Viral protein R (Vpr), an apoptogenic accessory protein encoded by HIV-1, induces mitochondrial membrane permeabilization (MMP) via a specific interaction with…”
Get full text

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope by Castedo, Maria, Roumier, Thomas, Blanco, Julià, Ferri, Karine F., Barretina, Jordi, Tintignac, Lionel A., Andreau, Karine, Perfettini, Jean-Luc, Amendola, Alessandra, Nardacci, Roberta, Leduc, Philip, Ingber, Donald E., Druillennec, Sabine, Roques, Bernard, Leibovitch, Serge A., Vilella-Bach, Montserrat, Chen, Jie, Este, José A., Modjtahedi, Nazanine, Piacentini, Mauro, Kroemer, Guido

“…Syncytia arising from the fusion of cells expressing the HIV‐1‐encoded Env gene with cells expressing the CD4/CXCR4 complex undergo apoptosis following the…”
Get full text

HIV-1 NCp7 as a target for the design of novel antiviral agents by Druillennec, S, Roques, B P

“…The treatment of AIDS, which is caused by the human immunodeficiency virus type-1 (HIV-1), has been significantly improved by the association of reverse…”
Get full text

Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas by Kannengiesser, Caroline, Spatz, Alain, Michiels, Stefan, Eychène, Alain, Dessen, Philippe, Lazar, Vladimir, Winnepenninckx, Véronique, Lesueur, Fabienne, Druillennec, Sabine, Robert, Caroline, van den Oord, Joost J., Sarasin, Alain, Bressac-de Paillerets, Brigitte

“…With the aim to correlate BRAF mutation status with gene expression in human primary cutaneous melanomas, and thus to get more insight on the consequences of…”
Get full text

Evidence of Interactions between the Nucleocapsid Protein NCp7 and the Reverse Transcriptase of HIV-1 by Druillennec, S, Caneparo, A, de Rocquigny, H, Roques, B P

“…The human immunodeficiency virus (HIV-1) nucleocapsid protein NCp7 containing two C X 2 C X 4 H X 4 C-type zinc fingers was proposed to be involved in reverse…”
Get full text

Efficient DNA Transfection Mediated by the C-Terminal Domain of Human Immunodeficiency Virus Type 1 Viral Protein R by Kichler, A, Pages, J C, Leborgne, C, Druillennec, S, Lenoir, C, Coulaud, D, Delain, E, Le Cam, E, Roques, B P, Danos, O

“…Author's Correction ( vol. 74 , p. 12003 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
Get full text

Development and characterization of ten monoclonal anti-Vpr antibodies by Sabbah, Emmanuelle N, Delaunay, Thierry, Varin, Audrey, Le-Rouzic, Erwann, Benichou, Serge, Herbein, Georges, Druillennec, Sabine, Roques, Bernard P

“…HIV-1 Vpr is a 96-amino acid auxiliary protein that performs numerous activities during viral infection. In the present study, 10 antibodies were generated…”
Get more information

Efficient DNA Transfection Mediated by the C-Terminal Domain of Human Immunodeficiency Virus Type 1 Viral Protein R by Kichler, Antoine, Pages, Jean-Christophe, Leborgne, Christian, Druillennec, Sabine, Lenoir, Christine, Coulaud, Dominique, Delain, Etionne, Le Cam, Eric, Roques, Bernard P., Danos, Olivier

Get full text

Nucleomimetic strategy for the inhibition of HIV-1 nucleocapsid protein NCp7 activities by Druillennec, Sabine, Meudal, Hervé, Roques, Bernard P., Fournié-Zaluski, Marie-Claude

“…We report the synthesis and biological properties of three modified dinucleotides T∗G, G∗T and T∗T in which the natural phosphodiester linkage has been…”
Get full text