Search Results - "DROOGMANS, G"

Cell Swelling, Heat, and Chemical Agonists Use Distinct Pathways for the Activation of the Cation Channel TRPV4 by Vriens, J., Watanabe, H., Janssens, A., Droogmans, G., Voets, T., Nilius, B.

“…TRPV4 is a Ca2+- and Mg2+-permeable cation channel within the vanilloid receptor subgroup of the transient receptor potential (TRP) family, and it has been…”
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Amazing chloride channels: an overview by Nilius, B., Droogmans, G.

“…Aim: This review describes molecular and functional properties of the following Cl – channels: the ClC family of voltage‐dependent Cl – channels, the…”
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Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2 by Hoenderop, J. G J, Vennekens, R., Muller, D., Prenen, J., Droogmans, G., Bindels, R. J M, Nilius, B.

“…The epithelial Ca 2+ channel (ECaC) family represents a unique group of Ca 2+ -selective channels that share limited homology to the ligand-gated capsaicin…”
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Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation by Cuppens, H, Lin, W, Jaspers, M, Costes, B, Teng, H, Vankeerberghen, A, Jorissen, M, Droogmans, G, Reynaert, I, Goossens, M, Nilius, B, Cassiman, J J

“…In congenital bilateral absence of the vas deferens patients, the T5 allele at the polymorphic Tn locus in the CFTR (cystic fibrosis transmembrane conductance…”
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Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells by Shen, Meng‐Ru, Droogmans, Guy, Eggermont, Jan, Voets, Thomas, Ellory, J. Clive, Nilius, Bernd

“…This study investigated the volume-regulated anion channel (VRAC) of human cervical cancer SiHa cells under various culture conditions, testing the hypothesis…”
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Transient receptor potential channels in endothelium: solving the calcium entry puzzle? by Nilius, Bernd, Droogmans, Guy, Wondergem, Robert

“…Many endothelial cell (EC) functions depend on influx of extracellular Ca2+, which is triggered by a variety of mechanical and chemical signals. Here, we…”
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Current understanding of mammalian TRP homologues by Vennekens, R, Voets, T, Bindels, R.J.M, Droogmans, G, Nilius, B

“…Calcium influx into the cell from the extracellular medium is crucial for important processes including muscle contraction, secretion and gene expression. This…”
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Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2 by Nilius, B., Prenen, J., Vennekens, R., Hoenderop, J.G.J., Bindels, R.J.M., Droogmans, G.

“…We have studied the modulation by intracellular Ca2+of the epithelial Ca2+channel, ECaC, heterologously expressed in HEK 293 cells. Whole-cell and inside-out…”
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Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells by Voets, T, Droogmans, G, Nilius, B

“…1. We have used the whole-cell patch-clamp technique to characterize the ionic conductances that determine the resting membrane potential in cultured…”
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Block of volume-regulated anion channels by selective serotonin reuptake inhibitors by Maertens, C, Droogmans, G, Verbesselt, R, Nilius, B

“…We have used the whole-cell patch clamp technique to study the effects of the commonly used antidepressants sertraline, paroxetine, citalopram and fluvoxamine…”
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Activation of a Cl- current by hypotonic volume increase in human endothelial cells by NILIUS, B, OIKE, M, ZAHRADNIK, I, DROOGMANS, G

“…We have used whole-cell and perforated patches to study ionic currents induced by hypotonic extracellular solutions (HTS, 185 mOsm instead of 290 mOsm) in…”
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Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins by Schwarz, G, Callewaert, G, Droogmans, G, Nilius, B

“…1. Changes of the free cytosolic Ca2+ concentration induced by shear stress were measured in Fura-2 acetoxymethyl ester-loaded endothelial cells from human…”
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Calcium-activated chloride channels in bovine pulmonary artery endothelial cells by Nilius, B, Prenen, J, Szücs, G, Wei, L, Tanzi, F, Voets, T, Droogmans, G

“…1. We characterized Ca(2+)-activated Cl- currents in calf pulmonary artery endothelial (CPAE) cells by using a combined patch clamp and fura-2…”
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Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3 by Papassotiriou, J, Eggermont, J, Droogmans, G, Nilius, B

“…Using the whole-cell patch-clamp technique, we have studied the electrophysiological and pharmacological properties of the Ca(2+)-activated Cl- current present…”
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Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells by Srinivas, S.P., Maertens, C., Goon, L.H., Goon, L., Satpathy, M., Yue, B.Y.J.T., Droogmans, G., Nilius, B.

“…Purpose. Hyposmolar perfusion of intact trabecular meshwork (TM) induces a decrease in its hydraulic conductivity (Lp). However, exposure to agents that…”
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Nonselective cation channels in endothelial cells derived from human umbilical vein by Kamouchi, M, Mamin, A, Droogmans, G, Nilius, B

“…(i) We have used a combined patch-clamp and fura-2 fluorescence technique to characterize a nonselective cation channel (NSC) in Ea. hy926 (EA) cells, an…”
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Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells by Kamouchi, M., Bremt, K., Eggermont, J., Droogmans, G., Nilius, B.

“…1. We have used the patch-clamp technique to study modulation of the inwardly rectifying K+ current (IK(IR)) in cultured bovine pulmonary artery endothelial…”
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Reduction of ionic strength activates single volume-regulated anion channels (VRAC) in endothelial cells by Sabirov, R Z, Prenen, J, Tomita, T, Droogmans, G, Nilius, B

“…We have previously shown that a reduction of intracellular ionic strength is involved in the activation of volume-regulated anion channels (VRAC). Here we show…”
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Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells by Schwarz, G, Droogmans, G, Nilius, B

“…1. Multiple effects of the imidazole compound SK&F 96365 have been evaluated on endothelial cells from human umbilical vein using a combined patch clamp and…”
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Extra- and intracellular proton-binding sites of volume-regulated anion channels by Sabirov, R Z, Prenen, J, Droogmans, G, Nilius, B

“…We have investigated the effects of extracellular and intracellular pH on single channel and macroscopic (macropatches) currents through volume-regulated anion…”
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