Search Results - "DRESCHER, W"

Circulating microRNAs as stable blood-based markers for cancer detection by Mitchell, Patrick S, Parkin, Rachael K, Kroh, Evan M, Fritz, Brian R, Wyman, Stacia K, Pogosova-Agadjanyan, Era L, Peterson, Amelia, Noteboom, Jennifer, O'Briant, Kathy C, Allen, April, Lin, Daniel W, Urban, Nicole, Drescher, Charles W, Knudsen, Beatrice S, Stirewalt, Derek L, Gentleman, Robert, Vessella, Robert L, Nelson, Peter S, Martin, Daniel B, Tewari, Muneesh

“…Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer…”
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Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries by Wyman, Stacia K, Parkin, Rachael K, Mitchell, Patrick S, Fritz, Brian R, O'Briant, Kathy, Godwin, Andrew K, Urban, Nicole, Drescher, Charles W, Knudsen, Beatrice S, Tewari, Muneesh

“…MicroRNAs (miRNAs) are small regulatory RNAs that are implicated in cancer pathogenesis and have recently shown promise as blood-based biomarkers for cancer…”
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Identification of novel candidate plasma metabolite biomarkers for distinguishing serous ovarian carcinoma and benign serous ovarian tumors by Buas, Matthew F, Gu, Haiwei, Djukovic, Danijel, Zhu, Jiangjiang, Drescher, Charles W, Urban, Nicole, Raftery, Daniel, Li, Christopher I

“…Abstract Objective Serous ovarian carcinoma (OC) represents a leading cause of cancer-related death among U.S. women. Non-invasive tools have recently emerged…”
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Quantitative global lipidomics analysis of patients with ovarian cancer versus benign adnexal mass by Buas, Matthew F., Drescher, Charles W., Urban, Nicole, Li, Christopher I., Bettcher, Lisa, Hait, Nitai C., Moysich, Kirsten B., Odunsi, Kunle, Raftery, Daniel, Yan, Li

“…Altered lipid metabolism has emerged as an important feature of ovarian cancer (OC), yet the translational potential of lipid metabolites to aid in diagnosis…”
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Longitudinal Screening Algorithm That Incorporates Change Over Time in CA125 Levels Identifies Ovarian Cancer Earlier Than a Single-Threshold Rule by Drescher, Charles W, Shah, Chirag, Thorpe, Jason, O'Briant, Kathy, Anderson, Garnet L, Berg, Christine D, Urban, Nicole, McIntosh, Martin W

“…Longitudinal algorithms incorporate change over time in biomarker levels to individualize screening decision rules. Compared with a single-threshold (ST) rule,…”
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Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: Evidence supporting a mesothelial-to-epithelial transition by Bendoraite, Ausra, Knouf, Emily C, Garg, Kavita S, Parkin, Rachael K, Kroh, Evan M, O'Briant, Kathy C, Ventura, Aviva P, Godwin, Andrew K, Karlan, Beth Y, Drescher, Charles W, Urban, Nicole, Knudsen, Beatrice S, Tewari, Muneesh

“…Abstract Objective Our objective was to characterize the expression and function of the miR-200 family of microRNAs (miRNA) in ovarian carcinogenesis. Methods…”
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DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines by Houshdaran, Sahar, Hawley, Sarah, Palmer, Chana, Campan, Mihaela, Olsen, Mari N, Ventura, Aviva P, Knudsen, Beatrice S, Drescher, Charles W, Urban, Nicole D, Brown, Patrick O, Laird, Peter W

“…Epithelial ovarian carcinoma is a significant cause of cancer mortality in women worldwide and in the United States. Epithelial ovarian cancer comprises…”
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Control of Tumor Initiation by NKG2D Naturally Expressed on Ovarian Cancer Cells by Cai, Xin, Caballero-Benitez, Andrea, Gewe, Mesfin M, Jenkins, Isaac C, Drescher, Charles W, Strong, Roland K, Spies, Thomas, Groh, Veronika

“…Abstract Cancer cells may co-opt the NKG2D lymphocyte receptor to complement the presence of its ligands for autonomous stimulation of oncogenic signaling…”
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A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: A Gynecologic Oncology Group study by Coleman, Robert L, Sill, Michael W, Lankes, Heather A, Fader, Amanda Nickles, Finkler, Neil J, Hoffman, James S, Rose, Peter G, Sutton, Gregory P, Drescher, Charles W, McMeekin, D. Scott, Hu, Wei, Deavers, Michael, Godwin, Andrew K, Alpaugh, R. Katherine, Sood, Anil K

“…Abstract Objectives Aflibercept targets vascular endothelial growth factor and placental growth factor. We evaluated activity and toxicity of aflibercept in…”
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An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription by Knouf, Emily C., Garg, Kavita, Arroyo, Jason D., Correa, Yesenia, Sarkar, Deepayan, Parkin, Rachael K., Wurz, Kaitlyn, O'Briant, Kathy C., Godwin, Andrew K., Urban, Nicole D., Ruzzo, Walter L., Gentleman, Robert, Drescher, Charles W., Swisher, Elizabeth M., Tewari, Muneesh

“…Although microRNAs (miRNAs) are important regulators of gene expression, the transcriptional regulation of miRNAs themselves is not well understood. We…”
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Bead-Based ELISA for Validation of Ovarian Cancer Early Detection Markers by SCHOLLER, Nathalie, CRAWFORD, Meghan, SATO, Alicia, DRESCHER, Charles W, O'BRIANT, Kathy C, KIVIAT, Nancy, ANDERSON, Garnet L, URBAN, Nicole

“…Purpose: Efforts to validate ovarian cancer early detection biomarkers with immunoassays are challenged by the limited specimen volumes available. We sought to…”
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Robotic surgery in gynecologic oncology: program initiation and outcomes after the first year with comparison with laparotomy for endometrial cancer staging by Veljovich, Dan S., MD, Paley, Pamela J., MD, Drescher, Charles W., MD, Everett, Elise N., MD, Shah, Chirag, MD, Peters, William A., MD

“…Objective The objective of the study was to evaluate outcomes during the first year of a robotic surgery program in gynecologic oncology. Study Design We…”
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Avascular necrosis after chemotherapy for haematological malignancy in childhood by Salem, K H, Brockert, A-K, Mertens, R, Drescher, W

“…Avascular necrosis (AVN) is a serious complication of high-dose chemotherapy for haematological malignancy in childhood. In order to describe its incidence and…”
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Antibody Immunity to the p53 Oncogenic Protein Is a Prognostic Indicator in Ovarian Cancer by GOODELL, Vivian, SALAZAR, Lupe G, URBAN, Nicole, DRESCHER, Charles W, GRAY, Heidi, SWENSEN, Ron E, MCLNTOSH, Martin W, DISIS, Mary L

“…Presence of intratumoral T-cell infiltration has been linked to improved survival in ovarian cancer patients. We questioned whether antibody immunity specific…”
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Proteins Associated with Cisplatin Resistance in Ovarian Cancer Cells Identified by Quantitative Proteomic Technology and Integrated with mRNA Expression Levels by Stewart, Jennifer J., White, James T., Yan, Xiaowei, Collins, Steven, Drescher, Charles W., Urban, Nicole D., Hood, Leroy, Lin, Biaoyang

“…Nearly all women diagnosed with ovarian cancer receive combination chemotherapy including cis- or carboplatin. Despite high initial response rates, resistance…”
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ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma by Salzman, Julia, Marinelli, Robert J, Wang, Peter L, Green, Ann E, Nielsen, Julie S, Nelson, Brad H, Drescher, Charles W, Brown, Patrick O

“…Every year, ovarian cancer kills approximately 14,000 women in the United States and more than 140,000 women worldwide. Most of these deaths are caused by…”
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Surgical outcomes in gynecologic oncology in the era of robotics: analysis of first 1000 cases by Paley, Pamela J., MD, Veljovich, Dan S., MD, Shah, Chirag A., MD, MPH, Everett, Elise N., MD, Bondurant, Amy E., MD, Drescher, Charles W., MD, Peters, William A., MD

“…Objective We sought to examine outcomes in an expanding robotic surgery (RS) program. Study Design In all, 1000 women underwent RS from May 2006 through…”
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Influence of Ovarian Cancer Risk Status on the Diagnostic Performance of the Serum Biomarkers Mesothelin, HE4, and CA125 by Shah, Chirag A, Lowe, Kimberly A, Paley, Pamela, Wallace, Erin, Anderson, Garnet L, McIntosh, Martin W, Andersen, M Robyn, Scholler, Nathalie, Bergan, Lindsay A, Thorpe, Jason D, Urban, Nicole, Drescher, Charles W

“…Objective: To evaluate the effect of ovarian cancer risk on the performance of the serum biomarkers mesothelin, human epididymis protein 4 (HE4), and CA125…”
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Effects of Personal Characteristics on Serum CA125, Mesothelin, and HE4 Levels in Healthy Postmenopausal Women at High-Risk for Ovarian Cancer by LOWE, Kimberly A, SHAH, Chirag, URBAN, Nicole, DRESCHER, Charles W, WALLACE, Erin, ANDERSON, Garnet, PALEY, Pamela, MCINTOSH, Martin, ANDERSEN, M. Robyn, SCHOLLER, Nathalie, BERGAN, Lindsay, THORPE, Jason

“…Objective: To evaluate if serum levels of candidate ovarian cancer biomarkers vary with individual characteristics of healthy women who are likely candidates…”
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Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains by Faça, Vitor M, Ventura, Aviva P, Fitzgibbon, Mathew P, Pereira-Faça, Sandra R, Pitteri, Sharon J, Green, Ann E, Ireton, Renee C, Zhang, Qing, Wang, Hong, O'Briant, Kathy C, Drescher, Charles W, Schummer, Michèl, McIntosh, Martin W, Knudsen, Beatrice S, Hanash, Samir M

“…Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies…”
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