Search Results - "DRENCKHAHN, D"

cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium by Baumer, Y., Drenckhahn, D., Waschke, J.

“…It is well established that cAMP stabilizes endothelial barrier functions, in part by regulation of VE-cadherin via EPAC/Rap 1. The aim of the present study…”
Get full text

Cadherin Interaction Probed by Atomic Force Microscopy by Baumgartner, W., Hinterdorfer, P., Ness, W., Raab, A., Vestweber, D., Schindler, H., Drenckhahn, D.

“…Single molecule atomic force microscopy was used to characterize structure, binding strength (unbinding force), and binding kinetics of a classical cadherin,…”
Get full text

Impact of Intrauterine Growth Restriction on the Capillarization of the Early Postnatal Rat Heart by Sutherland, Megan R., Ng, Ka Wing, Drenckhahn, Jörg D., Wlodek, Mary E., Black, Mary Jane

“…ABSTRACT Capillarization plays a key role in the growth of the developing heart. We therefore hypothesized that impaired heart development following…”
Get full text

Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery by Adamson, R H, Ly, J C, Sarai, R K, Lenz, J F, Altangerel, A, Drenckhahn, D, Curry, F E

“…Experiments in cultured endothelial cell monolayers demonstrate that increased intracellular cAMP strongly inhibits the acute permeability responses by both…”
Get more information

The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization by Schlegel, N, Burger, S, Golenhofen, N, Walter, U, Drenckhahn, D, Waschke, J

“…Regulation of actin dynamics is critical for endothelial barrier functions. We provide evidence that the actin-binding protein vasodilator-stimulated…”
Get more information

Preserved heart function after left ventricular pressure overload in adult mice subjected to neonatal cardiac hypoplasia by Heinecke, K, Heuser, A, Blaschke, F, Jux, C, Thierfelder, L, Drenckhahn, J-D

“…Intrauterine growth restriction in animal models reduces heart size and cardiomyocyte number at birth. Such incomplete cardiomyocyte endowment is believed to…”
Get more information

Regulation of actin dynamics is critical for endothelial barrier functions by Waschke, J, Curry, F E, Adamson, R H, Drenckhahn, D

“…We tested the hypothesis that the equilibrium between F- and G-actin in endothelial cells modulates the integrity of the actin cytoskeleton and is important…”
Get more information

Taste Receptor-Like Cells in the Rat Gut Identified by Expression of α -Gustducin by Höfer, D., Püschel, B., Drenckhahn, D.

“…The α -subunit of the trimeric G-protein complex specific for taste receptor cells of the tongue, α -gustducin, is described here to be also expressed in the…”
Get full text

cAMP protects endothelial barrier functions by preventing Rac-1 inhibition by Waschke, J, Drenckhahn, D, Adamson, R H, Barth, H, Curry, F E

“…cAMP enhances endothelial barrier properties and is protective against various inflammatory mediators both in vivo and in vitro. However, the mechanisms…”
Get more information

Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice by Adamson, R. H., Curry, F. E., Adamson, G., Liu, B., Jiang, Y., Aktories, K., Barth, H., Daigeler, A., Golenhofen, N., Ness, W., Drenckhahn, D.

“…Previous experiments using cultured endothelial monolayers indicate that Rho-family small GTPases are involved in modulation of endothelial monolayer…”
Get full text

Immunocytochemical characterization of two types of microvillar cells in rodent olfactory epithelium by Asan, E, Drenckhahn, D

“…Microvillar cells (MCs) have been identified in the olfactory epithelium of various mammalian species from rodents to humans. Studies on properties and…”
Get full text

Requirement of Rac activity for maintenance of capillary endothelial barrier properties by Waschke, J, Baumgartner, W, Adamson, R H, Zeng, M, Aktories, K, Barth, H, Wilde, C, Curry, F E, Drenckhahn, D

“…Our previous experiments indicated that GTPases, other than RhoA, are important for the maintenance of endothelial barrier integrity in both intact…”
Get more information

Physiological hydrostatic pressure protects endothelial monolayer integrity by Müller-Marschhausen, K, Waschke, J, Drenckhahn, D

“…Endothelial monolayer integrity is required to maintain endothelial barrier functions and has found to be impaired in several disorders like inflammatory…”
Get more information

Differential role of Rho GTPases in endothelial barrier regulation dependent on endothelial cell origin by Baumer, Y., Burger, S., Curry, F. E., Golenhofen, N., Drenckhahn, D., Waschke, J.

“…From studies using macrovascular endothelium, it was concluded that Rho A activation generally leads to endothelial barrier breakdown. Here, we characterized…”
Get full text

Ischemia-induced increase of stiffness of αB-crystallin/HSPB2-deficient myocardium by Golenhofen, N., Redel, A., Wawrousek, E. F., Drenckhahn, D.

Get full text

Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro by Waschke, J, Drenckhahn, D, Adamson, R H, Curry, F E

“…We demonstrated previously that inhibition of the small GTPase Rac-1 by Clostridium sordellii lethal toxin (LT) increased the hydraulic conductivity (L(p)) of…”
Get more information

Different Ca2+ affinities and functional implications of the two synaptic adhesion molecules cadherin-11 and N-cadherin by Heupel, W M, Baumgartner, W, Laymann, B, Drenckhahn, D, Golenhofen, N

“…Cadherins of synaptic complexes are considered to be critically involved in long-term potentiation (LTP). Here we compared biophysical properties of…”
Get full text

Identification of the taste cell G-protein, alpha-gustducin, in brush cells of the rat pancreatic duct system by Höfer, D, Drenckhahn, D

“…The major pancreatic excretory ducts have been shown to contain a large number of specialized epithelial cells, named brush cells, that are characterized by an…”
Get full text

Heterogeneity of Microvascular Pericytes for Smooth Muscle Type Alpha-Actin by Nehls, Volker, Drenckhahn, Detlev

“…Microvascular pericytes are believed to be involved in various functions such as regulation of capillary blood flow and endothelial proliferation. Since…”
Get full text

Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages by Feldmann, H, Bugany, H, Mahner, F, Klenk, H D, Drenckhahn, D, Schnittler, H J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text