Search Results - "DRAKULIC, Branko J"

Design, synthesis and biological evaluation of novel aryldiketo acids with enhanced antibacterial activity against multidrug resistant bacterial strains by Cvijetić, Ilija N., Verbić, Tatjana Ž., Ernesto de Resende, Pedro, Stapleton, Paul, Gibbons, Simon, Juranić, Ivan O., Drakulić, Branko J., Zloh, Mire

“…Antimicrobial resistance (AMR) is a major health problem worldwide, because of ability of bacteria, fungi and viruses to evade known therapeutic agents used in…”
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Structural modifications of 4-aryl-4-oxo-2-aminylbutanamides and their acetyl- and butyrylcholinesterase inhibitory activity. Investigation of AChE–ligand interactions by docking calculations and molecular dynamics simulations by Vitorović-Todorović, Maja D., Koukoulitsa, Catherine, Juranić, Ivan O., Mandić, Ljuba M., Drakulić, Branko J.

“…Congeneric set of thirty-eight 4-aryl-4-oxo-2-(N-aryl/cycloalkyl)butanamides has been designed, synthesized and evaluated for acetyl- and butyrylcholinesterase…”
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5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII by Cvijetić, Ilija N., Tanç, Muhammet, Juranić, Ivan O., Verbić, Tatjana Ž., Supuran, Claudiu T., Drakulić, Branko J.

“…[Display omitted] Inhibitory activity of a congeneric set of 23 phenyl-substituted 5-phenyl-pyrazole-3-carboxylic acids toward human carbonic anhydrase (hCA,…”
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(E)-4-aryl-4-oxo-2-butenoic acid amides, chalcone-aroylacrylic acid chimeras: design, antiproliferative activity and inhibition of tubulin polymerization by Vitorović-Todorović, Maja D, Erić-Nikolić, Aleksandra, Kolundžija, Branka, Hamel, Ernest, Ristić, Slavica, Juranić, Ivan O, Drakulić, Branko J

“…Antiproliferative activity of twenty-nine (E)-4-aryl-4-oxo-2-butenoic acid amides against three human tumor cell lines (HeLa, FemX, and K562) is reported…”
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Conformational mobility of active and E-64-inhibited actinidin by Grozdanović, Milica M., Drakulić, Branko J., Gavrović-Jankulović, Marija

“…Actinidin, a protease from kiwifruit, belongs to the C1 family of cysteine proteases. Cysteine proteases were found to be involved in many disease states and…”
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Antiproliferative activity of aroylacrylic acids. Structure-activity study based on molecular interaction fields by DRAKULIC, Branko J, STANOJKOVIC, Tatjana P, ZIZAK, Zeljko S, DABOVIC, Milan M

“…Antiproliferative activity of 27 phenyl-substituted 4-aryl-4-oxo-2-butenoic acids (aroylacrylic acids) toward Human cervix carcinoma (HeLa), Human chronic…”
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Role of complexes formation between drugs and penetration enhancers in transdermal delivery by Drakulić, Branko J., Juranić, Ivan O., Erić, Slavica, Zloh, Mire

“…The use of chemical penetration enhancers (CPE) is growing due to their ability to improve drug delivery through the skin. A possible mechanism of penetration…”
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Antiproliferative and antibacterial activity of some glutarimide derivatives by Popović-Djordjević, Jelena B, Klaus, Anita S, Žižak, Željko S, Matić, Ivana Z, Drakulić, Branko J

“…Antiproliferative and antibacterial activities of nine glutarimide derivatives (1-9) were reported. Cytotoxicity of compounds was tested toward three human…”
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Tautomerism of 4-phenyl-2,4-dioxobutanoic acid. Insights from pH ramping NMR study and quantum chemical calculations by Cvijetić, Ilija N., Pešić, Miloš P., Todorov, Miljana D., Drakulić, Branko J., Juranić, Ivan O., Verbić, Tatjana Ž., Zloh, Mire

“…Aryldiketo acids (ADKs) exhibit the variety of biological activities, mainly due to large affinity toward divalent metal ions. Metal complexation ability of…”
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Antiproliferative activity of the Michael adducts of aroylacrylic acids and cyclic amines by Juranic, Ivan O, Tosic, Ana V, Kolundzija, Branka, Drakulic, Branko J

“…Antiproliferative activity of twenty one Michael adducts of aroylacrylic acids and cyclic amines ( N -Me-piperazine, imidazole, 2-Me-imidazole, and indole) was…”
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Solvatochromism of symmetrical 2,6-distyrylpyridines. An experimental and theoretical study by Marković, Jelena M., Trišović, Nemanja P., Mutavdžić, Dragosav, Radotić, Ksenija, Juranić, Ivan O., Drakulić, Branko J., Marinković, Aleksandar D.

“…[Display omitted] •Synthesis and spectroscopic properties of symmetrical 2,6-distyrylpyridine derivatives are described.•Population of conformers in solution…”
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Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids by Cvijetic, Ilija, Verbic, Tatjana, Drakulic, Branko, Stankovic, Dalibor, Juranic, Ivan, Manojlovic, Dragan, Zloh, Mire

“…Redox properties of a set of aryldiketo acids (ADKs), small organic molecules that comprise 2,4-dioxobutanoic acid moiety, were studied. Along with well-known…”
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The 3D-QSAR study of 110 diverse, dual binding, acetylcholinesterase inhibitors based on alignment independent descriptors (GRIND-2). The effects of conformation on predictive power and interpretability of the models by Vitorović-Todorović, Maja D., Cvijetić, Ilija N., Juranić, Ivan O., Drakulić, Branko J.

“…[Display omitted] ► 3D QSAR study on the set of 110 diverse dual binding AChE inhibitors is reported. ► Three types of conformations were used for derivation…”
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Aryldiketo Acids Have Antibacterial Activity Against MDR Staphylococcus aureus Strains: Structural Insights Based on Similarity and Molecular Interaction Fields by Drakulić, Branko J., Stavri, Michael, Gibbons, Simon, Žižak, Željko S., Verbić, Tatjana Ž., Juranić, Ivan O., Zloh, Mire

“…Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction…”
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An alignment independent 3D QSAR study of the antiproliferative activity of 1,2,4,5-tetraoxanes by Cvijetić, Ilija N., Žižak, Željko P., Stanojković, Tatjana P., Juranić, Zorica D., Terzić, Nataša, Opsenica, Igor M., Opsenica, Dejan M., Juranić, Ivan O., Drakulić, Branko J.

“…An alignment-free 3D QSAR study on antiproliferative activity of the thirty-three 1,2,4,5-tetraoxane derivatives toward two human dedifferentiated cell lines…”
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4-Aryl-4-oxo- N-phenyl-2-aminylbutyramides as acetyl- and butyrylcholinesterase inhibitors. Preparation, anticholinesterase activity, docking study, and 3D structure–activity relationship based on molecular interaction fields by VITOROVIC-TODOROVIC, Maja D, JURANIC, Ivan O, MANDIC, Ljuba M, DRAKULIC, Branko J

“…Synthesis and anticholinesterase activity of 4-aryl-4-oxo- N-phenyl-2-aminylbutyramides, novel class of reversible, moderately potent cholinesterase…”
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Spectroscopic properties and antimicrobial activity of dioxomolybdenum(VI) complexes with heterocyclic S,S’-ligands by Sovilj Sofija P., Mitić Dragana, Drakulić Branko J., Milenković Marina

“…Five new dioxomolybdenum(VI) complexes of the general formula[MoO2(Rdtc)2], 1-5, where Rdtc-refer to piperidine- (Pipdtc), 4-morpholine-(Morphdtc),…”
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A QSAR study of acute toxicity of N-substituted fluoroacetamides to rats by Juranić, Ivan O., Drakulić, Branko J., Petrović, Slobodan D., Mijin, Dušan Ž., Stanković, Milena V.

“…Acute toxicity in vivo toward rats, of nineteen N-alkyl and N-cycloalkyl fluorocetamides [F–CH 2–C(O)–NH–R] was correlated with their structure-dependent…”
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2-[(Carboxymethyl)sulfanyl]-4-oxo-4-arylbutanoic Acids Selectively Suppressed Proliferation of Neoplastic Human HeLa Cells. A SAR/QSAR Study by DRAKULIC, Branko J, JURANIC, Zorica D, STANOJKOVIC, Tatjana P, JURANIC, Ivan O

“…A series of twenty alkyl-, halo-, and methoxy-aryl-substituted 2-[(carboxymethyl)sulfanyl]-4-oxo-4-arylbutanoic acids were synthesized. The new compounds,…”
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Weak intermolecular interactions in 11-chloro-2,3,4,5-tetrahydro-1H-cyclohepta[b]quinoline by Novakovic, Sladjana B, Vitorovic-Todorovic, Maja D, Bogdanovic, Goran A, Drakulic, Branko J

“…The title compound, C14H14ClN, is a chloro analogue of tacrine, an acetylcholinesterase inhibitor. The compound comprises a seven‐membered alicyclic ring whose…”
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