Search Results - "DOWELL, Barry"

Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer by RUDIN, Charles M, HANN, Christine L, RANSON, Malcolm R, DIVE, Caroline, MCKEEGAN, Evelyn M, CHYLA, Brenda J, DOWELL, Barry L, CHAKRAVARTTY, Arunava, NOLAN, Cathy E, RUDERSDORF, Niki, BUSMAN, Todd A, MABRY, Mack H, GARON, Edward B, KRIVOSHIK, Andrew P, HUMERICKHOUSE, Rod A, SHAPIRO, Geoffrey I, GANDHI, Leena, DE OLIVEIRA, Moacyr Ribeiro, BONOMI, Philip D, ROSS CAMIDGE, D, CHU, Quincy, GIACCONE, Giuseppe, KHAIRA, Divis, RAMALINGAM, Suresh S

“…Bcl-2 is a critical regulator of apoptosis that is overexpressed in the majority of small cell lung cancers (SCLC). Nativoclax (ABT-263) is a potent and…”
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Emerging Biomarkers for the Diagnosis and Prognosis of Prostate Cancer by Sardana, Girish, Dowell, Barry, Diamandis, Eleftherios P

“…Early detection of prostate cancer (CaP), the most prevalent cancer and the second-leading cause of death in men, has proved difficult, and current detection…”
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A comparative evaluation of Golgi protein-73, fucosylated hemopexin, α-fetoprotein, and PIVKA-II in the serum of patients with chronic hepatitis, cirrhosis, and hepatocellular carcinoma by Morota, Kaori, Nakagawa, Masatoshi, Sekiya, Rika, Hemken, Philip M, Sokoll, Lori J, Elliott, Debra, Chan, Daniel W, Dowell, Barry L

“…Golgi protein-73 (GP73) and fucosylated proteins have been proposed as potential serum markers for liver disease and/or hepatocellular carcinoma (HCC). The…”
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Plasma TIMP-1 and CEA in detection of primary colorectal cancer: a prospective, population based study of 4509 high-risk individuals by Nielsen, Hans J., Brünner, Nils, Jorgensen, Lars N., Olsen, Jesper, Rahr, Hans B., Thygesen, Knud, Hoyer, Ute, Laurberg, Søren, Stieber, Petra, Blankenstein, Marinus A., Davis, Gerard, Dowell, Barry L., Christensen, Ib J.

“…Abstract Objective. The combination of plasma tissue inhibitor of metalloproteinases-1 (TIMP-1) and carcinoembryonic antigen (CEA) may be valuable biomarkers…”
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Phase I/II Study of Pemetrexed With or Without ABT-751 in Advanced or Metastatic Non–Small-Cell Lung Cancer by RUDIN, Charles M, MAUER, Ann, JANE QIAN, PRADHAN, Rajendra, DOWELL, Barry, KRIVOSHIK, Andrew, GORDON, Gary, SMAKAL, Martin, JUERGENS, Rosalyn, SPELDA, Stanislav, WERTHEIM, Michael, COATES, Andrew, MCKEEGAN, Evelyn, ANSELL, Peter, XIANGDONG ZHOU

“…ABT-751 is an antimitotic and vascular disrupting agent with potent preclinical anticancer activity. We conducted a phase I and randomized double-blind phase…”
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Plasma biomarker signature associated with improved survival in advanced non-small cell lung cancer patients on linifanib by McKeegan, Evelyn M, Ansell, Peter J, Davis, Gerard, Chan, Sabrina, Chandran, Raj K, Gawel, Susan H, Dowell, Barry L, Bhathena, Anahita, Chakravartty, Arunava, McKee, Mark D, Ricker, Justin L, Carlson, Dawn M, Ramalingam, Suresh S, Devanarayan, Viswanath

“…Highlights • Linifanib is a potent and selective inhibitor of VEGF and PDGF receptors. • Linifanib has shown benefit in advanced NSCLC in first-line and…”
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Increased serological cancer-associated biomarker levels at large bowel endoscopy and risk of subsequent primary cancer by Hvolris, Martin H., Piper, Thomas B., Hammer, Emilie, Jørgensen, Lars N., Olsen, Jesper, Rahr, Hans B., Nielsen, Knud T., Laurberg, Søren, Christensen, Ib J., Brünner, Nils, Johansen, Julia S., Davis, Gerard J., Dowell, Barry L., Nielsen, Hans J.

“…Background: Frequently, subjects offered colonoscopy due to symptoms of colorectal neoplasia are diagnosed with diverticula. The symptoms may, however, also be…”
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870 Increased Soluble Cancer-Associated Biomarker Levels at Colonoscopy and Subsequent Long-Term Risk of Primary Cancer by Hvolris, Martin H, Piper, Thomas B, Hammer, Emilie, Jørgensen, Lars Nannestad, Olsen, Jesper, Rahr, Hans, Nielsen, Knud, Laurberg, Soren, Christensen, Ib J, Brünner, Nils, Johansen, Julia S, Davis, Gerard J, Dowell, Barry L, Nielsen, Hans J

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Biology and potential clinical implications of tissue inhibitor of metalloproteinases-1 in colorectal cancer treatment by Møller Sørensen, Nanna, Vejgaard Sørensen, Irene, Ørnbjerg Würtz, Sidse, Schrohl, Anne-Sofie, Dowell, Barry, Davis, Gerard, Jarle Christensen, Ib, Jørgen Nielsen, Hans, Brünner, Nils

“…Colorectal cancer (CRC) is the second leading cause of cancer-related death in the industrialized world. About half of "curatively" resected patients develop…”
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Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP) by Yoshimura, Toru, Fujita, Kenju, Kinukawa, Hideki, Matsuoka, Yoshiharu, Patil, Rahul D, Beligere, Gangamani S, Chan, Sabrina S, Dowell, Barry L, Sokoll, Lori, Elliott, Debra, Chan, Daniel W, Scheuer, Cornelia, Hofmann, Karin, Stieber, Petra, Sakurai, Yousuke, Iizuka, Masayuki, Saegusa, Haruhisa, Yamaguchi, Ken

“…Pro-gastrin releasing peptide (ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer…”
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Improvement and Multicenter Evaluation of the Analytical Performance of an Automated Chemiluminescent Immunoassay for Alpha Fetoprotein by Morota, Kaori, Komori, Makoto, Fujinami, Ryo, Yamada, Koji, Kuribayashi, Kageaki, Watanabe, Naoki, Sokoll, Lori J., Elliott, Debra, Chan, Daniel W., Martens, Frans, Heijboer, Annemieke C., Blankenstein, Marinus A., Hershberger, Stefan J., Pfeiffer, Zachary A., Vaidya, Shyam V., Dowell, Barry L.

“…Background A new ARCHITECT® alpha fetoprotein (AFP) assay was developed to improve the linearity at the upper end of the calibration curve and to enhance other…”
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Blood-based Biomarkers at Large Bowel Endoscopy and Prediction of Future Malignancies by Kring, Thomas S., Piper, Thomas B., Jørgensen, Lars N., Olsen, Jesper, Rahr, Hans B., Nielsen, Knud T., Laurberg, Søren, Davis, Gerard, Dowell, Barry, Johansen, Julia S., Christensen, Ib J., Brünner, Nils, Nielsen, Hans J.

“…Soluble cancer-related protein biomarker levels may be increased in subjects without findings at large bowel endoscopy performed due to symptoms associated…”
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Establishment and characterization of 7 new monoclonal antibodies to tissue inhibitor of metalloproteinases-1 by Møller Sørensen, Nanna, Dowell, Barry L, Stewart, Kent D, Jensen, Vibeke, Larsen, Lise, Lademann, Ulrik, Murphy, Gillian, Nielsen, Hans Jørgen, Brünner, Nils, Davis, Gerard J

“…Tissue inhibitor of metalloproteinases-1 (TIMP-1) plays a pivotal role in tissue remodeling processes, such as inflammation, wound healing and cancer invasion…”
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Determination and analysis of antigenic epitopes of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2) using synthetic peptides and computer modeling by Piironen, Timo, Villoutreix, Bruno O., Becker, Charlotte, Lilja, Hans, Hollingsworth, Kelly, Vihinen, Mauno, Bridon, Dominique, Qiu, Xiaoxing, Rapp, John, Dowell, Barry, Lövgren, Timo, Pettersson, Kim, Lilja, Hans

“…Prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2), produced essentially by the prostate gland, are 237‐amino acid monomeric proteins, with…”
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National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers by Sturgeon, Catharine M, Duffy, Michael J, Stenman, Ulf-Hakan, Lilja, Hans, Brunner, Nils, Chan, Daniel W, Babaian, Richard, Bast, Robert C., Jr, Dowell, Barry, Esteva, Francisco J, Haglund, Caj, Harbeck, Nadia, Hayes, Daniel F, Holten-Andersen, Mads, Klee, George G, Lamerz, Rolf, Looijenga, Leendert H, Molina, Rafael, Nielsen, Hans Jorgen, Rittenhouse, Harry, Semjonow, Axel, Shih, Ie-Ming, Sibley, Paul, Soletormos, Gyorgy, Stephan, Carsten, Sokoll, Lori, Hoffman, Barry R, Diamandis, Eleftherios P

“…Updated National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been…”
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Phase 2 trial of linifanib (ABT‐869) in patients with unresectable or metastatic hepatocellular carcinoma by Toh, Han Chong, Chen, Pei‐Jer, Carr, Brian I., Knox, Jennifer J., Gill, Sharlene, Ansell, Peter, McKeegan, Evelyn M., Dowell, Barry, Pedersen, Michelle, Qin, Qin, Qian, Jiang, Scappaticci, Frank A., Ricker, Justin L., Carlson, Dawn M., Yong, Wei Peng

“…BACKGROUND: The efficacy and safety of linifanib (ABT‐869), a selective inhibitor of vascular endothelial growth factor and platelet‐derived growth factor…”
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Plasma TIMP-1 and CEA as Markers for Detection of Primary Colorectal Cancer: A Prospective Validation Study Including Symptomatic and Non-symptomatic Individuals by Christensen, Ib Jarle, Brünner, Nils, Dowell, Barry, Davis, Gerard, Nielsen, Hans Jørgen, Newstead, Graham, King, Denis

“…The combination of plasma tissue inhibitor of metalloproteinases-1 (1) and CEA has been shown to have utility in early detection of colorectal cancer (2). A…”
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Increased cancer-associated protein biomarker levels at bowel endoscopy and risk of extra-colonic primary cancer by Piper, Thomas B, Hvolris, Martin H., Hammer, Emilie, Christensen, Ib J., Davis, Gerard, Dowell, Barry, Brunner, Nils, Nielsen, Hans J.

“…Abstract only…”
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The prognostic value of seven soluble proteins measured in plasma or serum from patients with colorectal cancer in TNM stages I-III by Christensen, Ib Jarle, Høyer-Hansen, Gunilla, Thurison, Tine, Dowell, Barry, Johansen, Julia S., Henriksen, Rikke, Rohrberg, Kristoffer Staal, Brunner, Nils, Nielsen, Hans J.

“…Abstract only 35 Background: In colorectal cancer (CRC) several independent blood-borne biomarkers have been proposed as prognostic and/or predictive markers…”
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Human T Cell Antigen Expression by Primate T Cells by Haynes, Barton F., Dowell, Barry L., Hensley, Lucinda L., Gore, Ira, Metzgar, Richard S.

“…Phylogenetic study in primates of the reactivity of 11 monoclonal antibodies to human T cells and rosette formation in the reaction of primate T cells with…”
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