Search Results - "DOUGLAS WEAVER, W"

Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy by Karaa, Amel, Haas, Richard, Goldstein, Amy, Vockley, Jerry, Weaver, W Douglas, Cohen, Bruce H

“…OBJECTIVETo assess the safety and efficacy of elamipretide, an aromatic-cationic tetrapeptide that readily penetrates cell membranes and transiently localizes…”
Get full text

Appropriateness of Percutaneous Coronary Intervention by Chan, Paul S, Patel, Manesh R, Klein, Lloyd W, Krone, Ronald J, Dehmer, Gregory J, Kennedy, Kevin, Nallamothu, Brahmajee K, Weaver, W. Douglas, Masoudi, Frederick A, Rumsfeld, John S, Brindis, Ralph G, Spertus, John A

“…CONTEXT Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown…”
Get full text

Inflammatory Biomarkers Interleukin‐6 and C‐Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial by Held, Claes, White, Harvey D., Stewart, Ralph A. H., Budaj, Andrzej, Cannon, Christopher P., Hochman, Judith S., Koenig, Wolfgang, Siegbahn, Agneta, Steg, Philippe Gabriel, Soffer, Joseph, Weaver, W. Douglas, Östlund, Ollie, Wallentin, Lars

“…Background Evaluation of cardiovascular prognosis in patients with stable coronary heart disease is based on clinical characteristics and biomarkers indicating…”
Get full text

The NCDR CathPCI Registry: a US national perspective on care and outcomes for percutaneous coronary intervention by Moussa, Issam, Hermann, Anthony, Messenger, John C, Dehmer, Gregory J, Weaver, W Douglas, Rumsfeld, John S, Masoudi, Frederick A

“…The NCDR CathPCI Registry collects detailed clinical, process-of-care and outcomes data for patients undergoing coronary angiography and percutaneous coronary…”
Get more information

International Variation in and Factors Associated With Hospital Readmission After Myocardial Infarction by Kociol, Robb D, Lopes, Renato D, Clare, Robert, Thomas, Laine, Mehta, Rajendra H, Kaul, Padma, Pieper, Karen S, Hochman, Judith S, Weaver, W. Douglas, Armstrong, Paul W, Granger, Christopher B, Patel, Manesh R

“…CONTEXT ST-segment elevation myocardial infarction (STEMI) treatment has improved outcomes and shortened hospital stay. Recently, 30-day readmission rates have…”
Get full text

Comparison of Clinical Interpretation With Visual Assessment and Quantitative Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention in Contemporary Practice: The Assessing Angiography (A2) Project by NALLAMOTHU, Brahmajee K, SPERTUS, John A, KOENIG, Gerald C, WAITES, Thad F, GANTT, D. Scott, KICHURA, George, CHAZAL, Richard A, O'BRIEN, Peter K, VALENTINE, C. Michael, RUMSFELD, John S, REIBER, Johan H. C, ELMORE, Joann G, LANSKY, Alexandra J, KRUMHOLZ, Richard A, DOUGLAS WEAVER, W, KRUMHOLZ, Harlan M, COHEN, David J, JONES, Philip G, KURESHI, Faraz, DEHMER, Gregory J, DROZDA, Joseph P, NORINE WALSH, Mary, BRUSH, John E

“…Studies conducted decades ago described substantial disagreement and errors in physicians' angiographic interpretation of coronary stenosis severity. Despite…”
Get full text

Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study by Bagai, Akshay, MD, MHS, Armstrong, Paul W., MD, Stebbins, Amanda, MS, Mahaffey, Kenneth W., MD, Hochman, Judith S., MD, Weaver, W. Douglas, MD, Patel, Manesh R., MD, Granger, Christopher B., MD, Lopes, Renato D., MD, PhD

“…Background Left ventricular end-diastolic pressure (LVEDP) is frequently measured during primary percutaneous coronary intervention (PCI). However, little is…”
Get full text

Trends in reperfusion strategies, door-to-needle and door-to-balloon times, and in-hospital mortality among patients with ST-segment elevation myocardial infarction enrolled in the National Registry of Myocardial Infarction from 1990 to 2006 by Gibson, C. Michael, MS, MD, Pride, Yuri B., MD, Frederick, Paul D., MPH, MBA, Pollack, Charles V., MA, MD, Canto, John G., MD, Tiefenbrunn, Alan J., MD, Weaver, W. Douglas, MD, Lambrew, Costas T., MD, French, William J., MD, Peterson, Eric D., MD, MPH, Rogers, William J., MD

“…Background Among patients with ST-segment elevation myocardial infarction (STEMI), rapid reperfusion is associated with improved mortality. As such,…”
Get full text

Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome by Lindholm, Daniel, James, Stefan K, Bertilsson, Maria, Becker, Richard C, Cannon, Christopher P, Giannitsis, Evangelos, Harrington, Robert A, Himmelmann, Anders, Kontny, Frederic, Siegbahn, Agneta, Steg, Philippe Gabriel, Storey, Robert F, Velders, Matthijs A, Weaver, W Douglas, Wallentin, Lars

“…Risk stratification in non-ST-elevation acute coronary syndrome (NSTE-ACS) is currently mainly based on clinical characteristics. With routine invasive…”
Get full text

Rationale and design of the EMBRACE STEMI Study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction by Chakrabarti, Anjan K., MD, Feeney, Kristin, BS, Abueg, Cassandra, MPH, Brown, David A., PhD, Czyz, Ewa, MD, Tendera, Michal, MD, Janosi, Andras, MD, Giugliano, Robert P., MD, Kloner, Robert A., MD, PhD, Weaver, W. Douglas, MD, Bode, Christoph, MD, Godlewski, Jacek, MD, Merkely, Bela, PhD, DSc, Gibson, C. Michael, MS, MD

“…Background Although significant efforts have been made to improve ST-segment elevation myocardial infarction (STEMI) outcomes by reducing…”
Get full text

Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes by Vavalle, John P., MD, MHS, van Diepen, Sean, MD, Clare, Robert M., MS, Hochman, Judith S., MD, Weaver, W. Douglas, MD, Mehta, Rajendra H., MD, Pieper, Karen S., MS, Patel, Manesh R., MD, Patel, Uptal D., MD, Armstrong, Paul W., MD, Granger, Christopher B., MD, Lopes, Renato D., MD, PhD

“…Background Among patients presenting with ST-segment elevation myocardial infarction (STEMI) for primary percutaneous coronary intervention (PCI), the…”
Get full text

Lipoprotein‐Associated Phospholipase A2 Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease by Wallentin, Lars, Held, Claes, Armstrong, Paul W., Cannon, Christopher P., Davies, Richard Y., Granger, Christopher B., Hagström, Emil, Harrington, Robert A., Hochman, Judith S., Koenig, Wolfgang, Krug‐Gourley, Sue, Mohler, Emile R., Siegbahn, Agneta, Tarka, Elizabeth, Steg, Philippe Gabriel, Stewart, Ralph A. H., Weiss, Robert, Östlund, Ollie, White, Harvey D., Budaj, Andrzej, Ardissino, Diego, Avezum, Alvaro, Aylward, Philip E., Bryce, Alfonso, Chen, Hong, Chen, Ming‐Fong, Corbalan, Ramon, Dalby, Anthony J., Danchin, Nicolas, De Winter, Robbert J., Denchev, Stefan, Diaz, Rafael, Elisaf, Moses, Flather, Marcus D., Goudev, Assen R., Grinfeld, Liliana, Husted, Steen, Kim, Hyo‐Soo, Linhart, Ales, Lonn, Eva, López‐Sendón, José, Manolis, Athanasios J., Nicolau, José C., Pais, Prem, Parkhomenko, Alexander, Pedersen, Terje R., Pella, Daniel, Ramos‐Corrales, Marco A., Ruda, Mikhail, Sereg, Mátyás, Siddique, Saulat, Sinnaeve, Peter, Sritara, Piyamitr, Swart, Henk P., Sy, Rody G., Teramoto, Tamio, Tse, Hung‐Fat, Weaver, W. Douglas, Viigimaa, Margus, Vinereanu, Dragos, Zhu, Junren

“…Background We evaluated lipoprotein‐associated phospholipase A2 (Lp‐PLA2) activity in patients with stable coronary heart disease before and during treatment…”
Get full text

Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction : results from the CARDINAL study by VOGELZANG, Mathijs, ZIJISTRA, Felix, TODARO, Thomas G, MOJCIK, Christopher F, ARMSTRONG, Paul W, GRANGER, Christopher B, GOYAL, Abhinav, MAHAFFEY, Kenneth W, GARG, Jyotsna, NICOLAU, Jose C, HOCHMAN, Judith S, WEAVER, W. Douglas, THEROUX, Pierre, OLIVEIRA, Gustavo B. F

“…In acute myocardial infarction (AMI), baseline hyperglycaemia predicts adverse outcomes, but the relation between subsequent change in glucose levels and…”
Get full text

Current Status of Preventive Cardiology Training Among United States Cardiology Fellowships and Comparison to Training Guidelines by Pack, Quinn R., MD, Keteyian, Steven J., PhD, McBride, Patrick E., MD, MPH, Weaver, W. Douglas, MD, Kim, Henry E., MD, MPH

“…We evaluated preventive cardiology education in United States cardiology fellowship programs and their adherence to Core Cardiovascular Training Symposium…”
Get full text

A meta-analysis of randomized control trials comparing minimally invasive direct coronary bypass grafting versus percutaneous coronary intervention for stenosis of the proximal left anterior descending artery by Jaffery, Zehra, Kowalski, Marcin, Weaver, W. Douglas, Khanal, Sanjaya

“…Percutaneous intervention (PCI) and minimally invasive direct coronary bypass grafting (MIDCAB) are both well-accepted treatment options for isolated…”
Get full text

The Impact of Extreme-Risk Cases on Hospitals’ Risk-Adjusted Percutaneous Coronary Intervention Mortality Ratings by Sherwood, Matthew W., MD, MHS, Brennan, J. Matthew, MD, MPH, Ho, Kalon K., MD, Masoudi, Frederick A., MD, MSPH, Messenger, John C., MD, Weaver, W. Douglas, MD, Dai, David, MS, Peterson, Eric D., MD, MPH

“…Abstract Objectives The goal of this study was to examine the calibration of a validated risk-adjustment model in very high-risk percutaneous coronary…”
Get full text

Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial) by Daaboul, Yazan, MD, Korjian, Serge, MD, Weaver, W. Douglas, MD, Kloner, Robert A., MD, PhD, Giugliano, Robert P., MD, SM, Carr, Jim, PharmD, Neal, Brandon J., MPH, Chi, Gerald, MD, Cochet, Madeleine, BS, Goodell, Laura, BS, Michalak, Nathan, BA, Rusowicz-Orazem, Luke, BS, Alkathery, Turky, MD, Allaham, Haytham, MD, Routray, Sujit, MD, Szlosek, Donald, MPH, Jain, Purva, MPH, Gibson, C. Michael, MD, MS

“…Biomarker measures of infarct size and myocardial salvage index (MSI) are important surrogate measures of clinical outcomes after a myocardial infarction…”
Get full text

ACC/AHA clinical performance measures for adults with ST-elevation and non-ST-elevation myocardial infarction : A report of the american college of cardiology/american heart association task force on performance measures (writing committee to develop performance measures on ST-elevation and non-ST-elevation myocardial infarction) by KRUMHOLZ, Harlan M, ANDERSON, Jeffrey L, BURKE, Gregory, EAGLE, Kim A, LAMBREW, Costas T, LINDERBAUM, Jane, MASOUDI, Frederick A, NORMAND, Sharon-Lise T, PINA, Ileana L, RADFORD, Martha J, RUMSFELD, John S, BROOKS, Neil H, RITCHIE, James L, SPERTUS, John A, FESMIRE, Francis M, LANDRUM, Mary Beth, WEAVER, W. Douglas, WHYTE, John, BONOW, Robert O, BENNETT, Susan J

Get full text

Misdiagnosis of atrial fibrillation and its clinical consequences by Bogun, Frank, Anh, Daejoon, Kalahasty, Gautham, Wissner, Erik, Bou Serhal, Chadi, Bazzi, Rabih, Weaver, W Douglas, Schuger, Claudio

“…Computer algorithms are often used for cardiac rhythm interpretation and are subsequently corrected by an overreading physician. The purpose of this study was…”
Get more information

Mortality Implications of Primary Percutaneous Coronary Intervention Treatment Delays: Insights From the Assessment of Pexelizumab in Acute Myocardial Infarction Trial by HUDSON, Michael P, ARMSTRONG, Paul W, GRANGER, Christopher B, O'NEIL, William W, STEBBINS, Amanda L, DOUGLAS WEAVER, W, WIDIMSKY, Petr, AYLWARD, Philip E, RUZYLLO, Witold, HOLMES, David, MAHAFFEY, Kenneth W

“…Prior studies demonstrate a direct relationship between treatment delays to primary percutaneous intervention and mortality in patients with ST-segment…”
Get full text