Search Results - "DOUGLAS, IAN"

Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK by Bhaskaran, Krishnan, dos-Santos-Silva, Isabel, Leon, David A, Douglas, Ian J, Smeeth, Liam

“…BMI is known to be strongly associated with all-cause mortality, but few studies have been large enough to reliably examine associations between BMI and a…”
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Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults by Bhaskaran, Krishnan, Dr, Douglas, Ian, PhD, Forbes, Harriet, MSc, dos-Santos-Silva, Isabel, Prof, Leon, David A, Prof, Smeeth, Liam, Prof

“…Summary Background High body-mass index (BMI) predisposes to several site-specific cancers, but a large-scale systematic and detailed characterisation of…”
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AVERT: A novel approach to wildlife rescue and welfare in Australia by Douglas, Ian

“…In the immediate aftermath of the summer bushfires in Australia in 2019–20, the Australian Veterinary Emergency Response Team (AVERT) was mobilised for the…”
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Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care by Douglas, Ian J, Bhaskaran, Krishnan, Batterham, Rachel L, Smeeth, Liam

“…Bariatric surgery is becoming a more widespread treatment for obesity. Comprehensive evidence of the long-term effects of contemporary surgery on a broad range…”
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Factors associated with COVID-19-related death using OpenSAFELY by Williamson, Elizabeth J., Walker, Alex J., Bhaskaran, Krishnan, Bacon, Seb, Bates, Chris, Morton, Caroline E., Curtis, Helen J., Mehrkar, Amir, Evans, David, Inglesby, Peter, Cockburn, Jonathan, McDonald, Helen I., MacKenna, Brian, Tomlinson, Laurie, Douglas, Ian J., Rentsch, Christopher T., Mathur, Rohini, Wong, Angel Y. S., Grieve, Richard, Harrison, David, Forbes, Harriet, Schultze, Anna, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Perera, Rafael, Evans, Stephen J. W., Smeeth, Liam, Goldacre, Ben

“…Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide 1 . There is unprecedented urgency to understand who is most at risk of severe…”
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Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015 by Sinnott, Sarah-Jo, Smeeth, Liam, Williamson, Elizabeth, Douglas, Ian J

“…Objective To estimate the incidence and prevalence of resistant hypertension among a UK population treated for hypertension from 1995 to 2015.Design Cohort…”
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Exacerbation risk and characterisation of the UK's asthma population from infants to old age by Bloom, Chloe I, Nissen, Francis, Douglas, Ian J, Smeeth, Liam, Cullinan, Paul, Quint, Jennifer K

“…Few studies have examined the characteristics of a general asthma population; most have focused on more severe patients or severe exacerbations. This…”
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BMI and risk of dementia in two million people over two decades: a retrospective cohort study by Qizilbash, Nawab, Dr, Gregson, John, PhD, Johnson, Michelle E, MSc, Pearce, Neil, Prof, Douglas, Ian, PhD, Wing, Kevin, MSc, Evans, Stephen J W, Prof, Pocock, Stuart J, Prof

“…Summary Background Dementia and obesity are increasingly important public health issues. Obesity in middle age has been proposed to lead to dementia in old…”
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Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study by Rentsch, Christopher T, Beckman, Joshua A, Tomlinson, Laurie, Gellad, Walid F, Alcorn, Charles, Kidwai-Khan, Farah, Skanderson, Melissa, Brittain, Evan, King, Jr, Joseph T, Ho, Yuk-Lam, Eden, Svetlana, Kundu, Suman, Lann, Michael F, Greevy, Jr, Robert A, Ho, P Michael, Heidenreich, Paul A, Jacobson, Daniel A, Douglas, Ian J, Tate, Janet P, Evans, Stephen J W, Atkins, David, Justice, Amy C, Freiberg, Matthew S

“…To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among…”
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Global airline alliances and profitability: A difference-in-difference analysis by Douglas, Ian, Tan, David

“…•No evidence that the formation of global alliances improved the profitability of member airlines.•Result is robust across geographic regions, individual…”
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Sterilizable Gels from Thermoresponsive Block Copolymer Worms by Blanazs, Adam, Verber, Robert, Mykhaylyk, Oleksandr O, Ryan, Anthony J, Heath, Jason Z, Douglas, C. W. Ian, Armes, Steven P

“…Biocompatible hydrogels have many applications, ranging from contact lenses to tissue engineering scaffolds. In most cases, rigorous sterilization is…”
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Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform by Mathur, Rohini, Rentsch, Christopher T, Morton, Caroline E, Hulme, William J, Schultze, Anna, MacKenna, Brian, Eggo, Rosalind M, Bhaskaran, Krishnan, Wong, Angel Y S, Williamson, Elizabeth J, Forbes, Harriet, Wing, Kevin, McDonald, Helen I, Bates, Chris, Bacon, Seb, Walker, Alex J, Evans, David, Inglesby, Peter, Mehrkar, Amir, Curtis, Helen J, DeVito, Nicholas J, Croker, Richard, Drysdale, Henry, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Tomlinson, Laurie, Evans, Stephen J W, Grieve, Richard, Harrison, David, Rowan, Kathy, Khunti, Kamlesh, Chaturvedi, Nishi, Smeeth, Liam, Goldacre, Ben

“…COVID-19 has disproportionately affected minority ethnic populations in the UK. Our aim was to quantify ethnic differences in SARS-CoV-2 infection and COVID-19…”
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Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database by Zhou, Xiaofeng, Douglas, Ian. J., Shen, Rongjun, Bate, Andrew

“…Introduction The Self-Controlled Case Series (SCCS) method has been widely used for hypothesis testing, but there is limited evidence of its performance for…”
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Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February by Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen Jw, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Ys, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M

“…The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is…”
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Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink by Matthews, Anthony, Langan, Sinéad M, Douglas, Ian J, Smeeth, Liam, Bhaskaran, Krishnan

“…Laboratory evidence suggests that reduced phosphodiesterase type 5 (PDE5) expression increases the invasiveness of melanoma cells; hence, pharmacological…”
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Exposure to antipsychotics and risk of stroke: self controlled case series study by Douglas, Ian J, Smeeth, Liam

“…Objectives To investigate the association between use of typical and atypical antipsychotic drugs and incidence of stroke in patients with and without…”
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50 years change in urban land use and ecological planning globally in the era of design with nature by Douglas, Ian

“…Ian McHarg's 1969 book, Design with Nature, was grounded in earlier good practice, especially the European vision of fitting cities into the regional landscape…”
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Methods for drug safety signal detection using routinely collected observational electronic health care data: A systematic review by Coste, Astrid, Wong, Angel, Bokern, Marleen, Bate, Andrew, Douglas, Ian J.

“…Purpose Signal detection is a crucial step in the discovery of post‐marketing adverse drug reactions. There is a growing interest in using routinely collected…”
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Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England by Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M

“…Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha variant (B.1.1.7) is associated with higher transmissibility than…”
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Cardiovascular outcomes associated with use of clarithromycin: population based study by Wong, Angel Y S, Root, Adrian, Douglas, Ian J, Chui, Celine S L, Chan, Esther W, Ghebremichael-Weldeselassie, Yonas, Siu, Chung-Wah, Smeeth, Liam, Wong, Ian C K

“…Study question What is the association between clarithromycin use and cardiovascular outcomes?Methods In this population based study the authors compared…”
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