Search Results - "DOUGLAS, C"

Mitochondrial genetic medicine by Wallace, Douglas C.

“…Inherited mitochondrial DNA (mtDNA) diseases were discovered 30 years ago, and their characterization has provided a new perspective on the etiology of the…”
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Mitochondria and cancer by Wallace, Douglas C.

“…Key Points Warburg observed, 70 years ago, that tumours produce excess lactate in the presence of oxygen. This became known as aerobic glycolysis or the…”
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Mitochondrial DNA Variation in Human Radiation and Disease by Wallace, Douglas C.

“…Environmental adaptation, predisposition to common diseases, and, potentially, speciation may all be linked through the adaptive potential of mitochondrial DNA…”
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Structural Enzymology of Nitrogenase Enzymes by Einsle, Oliver, Rees, Douglas C

“…The reduction of dinitrogen to ammonia by nitrogenase reflects a complex choreography involving two component proteins, MgATP and reductant. At center stage of…”
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A mitochondrial bioenergetic etiology of disease by Wallace, Douglas C

“…The classical Mendelian genetic perspective has failed to adequately explain the biology and genetics of common metabolic and degenerative diseases. This is…”
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Mitochondrial Etiology of Neuropsychiatric Disorders by Pei, Liming, Wallace, Douglas C.

“…The brain has the highest mitochondrial energy demand of any organ. Therefore, subtle changes in mitochondrial energy production will preferentially affect the…”
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The rise of mitochondria in medicine by Picard, Martin, Wallace, Douglas C, Burelle, Yan

“…Once considered exclusively the cell's powerhouse, mitochondria are now recognized to perform multiple essential functions beyond energy production, impacting…”
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Supply chain transparency: A bibliometric review and research agenda by Montecchi, Matteo, Plangger, Kirk, West, Douglas C.

“…Many organizations are confronted with the challenge of improving supply chain transparency not only to meet regulatory requirements, but also to optimize…”
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Mitochondrial DNA mutations in disease and aging by Wallace, Douglas C

“…The human mitochondrial genome involves over 1,000 genes, dispersed across the maternally inherited mitochondrial DNA (mtDNA) and the biparentally inherited…”
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Historical Developments in Hydroprocessing Bio-oils by Elliott, Douglas C

“…This paper is a review of the developments in the field of catalytic hydroprocessing of biomass-derived liquefaction conversion products (bio-oil) over the…”
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Defining the Public Health Threat of Food Fraud by Spink, John, Moyer, Douglas C.

“…:  Food fraud, including the more defined subcategory of economically motivated adulteration, is a food risk that is gaining recognition and concern…”
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Shape Memory Bulk Metallic Glass Composites by Hofmann, Douglas C.

“…Glass-forming and shape memory metals may provide a route to fabricating materials with enhanced mechanical properties. Bulk metallic glasses (BMGs) are being…”
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Genetics: Mitochondrial DNA in evolution and disease by Wallace, Douglas C

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Bioenergetics in human evolution and disease: implications for the origins of biological complexity and the missing genetic variation of common diseases by Wallace, Douglas C.

“…Two major inconsistencies exist in the current neo-Darwinian evolutionary theory that random chromosomal mutations acted on by natural selection generate new…”
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ABC transporters: the power to change by Rees, Douglas C, Lewinson, Oded, Johnson, Eric

“…Key Points ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered…”
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Dynamical evolution of black hole subsystems in idealized star clusters by Breen, Philip G., Heggie, Douglas C.

“…In this paper, globular star clusters which contain a subsystem of stellar mass black holes (BH) are investigated. This is done by considering two-component…”
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Towards an N-body model for the globular cluster M4 by Heggie, Douglas C.

“…This paper describes an N-body model for the dynamical evolution of the nearby globular cluster M4. The initial conditions, with N = 484 710 particles, were…”
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The health equity measurement framework: a comprehensive model to measure social inequities in health by Dover, Douglas C, Belon, Ana Paula

“…Despite the wealth of frameworks on social determinants of health (SDOH), two current limitations include the relative superficial description of factors…”
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Calcium Supplements and Fracture Prevention by Bauer, Douglas C

“…This article reviews recommendations regarding calcium intake and uncertainty about benefits as well as potential risks of calcium supplementation. In…”
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Clinical Use of Bone Turnover Markers by Bauer, Douglas C

“…This JAMA Insights Clinical Update reviews bone turnover markers measurable in blood and urine and summarizes evidence supporting their use to predict…”
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