Search Results - "DOSTROVSKY, Jonathan O"

Beta Oscillatory Activity in the Subthalamic Nucleus and Its Relation to Dopaminergic Response in Parkinson's Disease by Weinberger, Moran, Mahant, Neil, Hutchison, William D, Lozano, Andres M, Moro, Elena, Hodaie, Mojgan, Lang, Anthony E, Dostrovsky, Jonathan O

“…1 Department of Physiology, 2 Toronto Western Hospital, Division of Neurosurgery, and 3 Department of Medicine, Division of Neurology, University of Toronto;…”
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Chronic Anterior Thalamus Stimulation for Intractable Epilepsy by Hodaie, Mojgan, Wennberg, Richard A., Dostrovsky, Jonathan O., Lozano, Andres M.

“…Purpose: A significant number of patients with epilepsy remain poorly controlled despite antiepileptic medication (AED) treatment and are not eligible for…”
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Role of Glia in Orofacial Pain by Chiang, Chen-Yu, Dostrovsky, Jonathan O., Iwata, Koichi, Sessle, Barry J.

“…Several acute and chronic pain conditions in the face or mouth are very common, and some are unique to the orofacial region. However, the etiology and…”
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Astroglia in Medullary Dorsal Horn (Trigeminal Spinal Subnucleus Caudalis) Are Involved in Trigeminal Neuropathic Pain Mechanisms by Okada-Ogawa, Akiko, Suzuki, Ikuko, Sessle, Barry J, Chiang, Chen-Yu, Salter, Michael W, Dostrovsky, Jonathan O, Tsuboi, Yoshiyuki, Kondo, Masahiro, Kitagawa, Junichi, Kobayashi, Azusa, Noma, Noboru, Imamura, Yoshiki, Iwata, Koichi

“…The aim of this study was to investigate whether astroglia in the medullary dorsal horn (trigeminal spinal subnucleus caudalis; Vc) may be involved in…”
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Oscillatory activity in the globus pallidus internus: Comparison between Parkinson’s disease and dystonia by Weinberger, Moran, Hutchison, William D, Alavi, Mahan, Hodaie, Mojgan, Lozano, Andres M, Moro, Elena, Dostrovsky, Jonathan O

“…Highlights ► 30% of globus pallidus neurons in Parkinson’s disease patients have 11–30 Hz beta oscillatory activity. ► Globus pallidus firing is coherent with…”
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The gap junction blocker carbenoxolone attenuates nociceptive behavior and medullary dorsal horn central sensitization induced by partial infraorbital nerve transection in rats by Wang, Hua, Cao, Ye, Chiang, Chen-Yu, Dostrovsky, Jonathan O., Sessle, Barry J.

“…The gap junction blocker carbenoxolone attenuated nociceptive behavior and central sensitization of medullary dorsal horn nociceptive neurons induced by…”
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Pregabalin suppresses nociceptive behavior and central sensitization in a rat trigeminal neuropathic pain model by Cao, Ye, Wang, Hua, Chiang, Chen-Yu, Dostrovsky, Jonathan O, Sessle, Barry J

“…The aim of this study was to determine whether pregabalin affects nociceptive behavior and central sensitization in a trigeminal neuropathic pain model. A…”
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Deep brain stimulation for chronic neuropathic pain: Long-term outcome and the incidence of insertional effect by Hamani, Clement, Schwalb, Jason M., Rezai, Ali R., Dostrovsky, Jonathan O., Davis, Karen D., Lozano, Andres M.

“…We conducted a retrospective analysis of long-term results of deep brain stimulation (DBS) for the treatment of neuropathic pain. Twenty-one patients had…”
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Frequency-dependent effects of electrical stimulation in the globus pallidus of dystonia patients by Liu, Liu D, Prescott, Ian A, Dostrovsky, Jonathan O, Hodaie, Mojgan, Lozano, Andres M, Hutchison, William D

“…Deep brain stimulation (DBS) in the globus pallidus internus (GPi) has been shown to improve dystonia, a movement disorder of repetitive twisting movements and…”
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Selective enhancement of rapid eye movement sleep by deep brain stimulation of the human pons by Lim, Andrew S., Moro, Elena, Lozano, Andres M., Hamani, Clement, Dostrovsky, Jonathan O., Hutchison, William D., Lang, Anthony E., Wennberg, Richard A., Murray, Brian J.

“…Animal studies suggest that rapid eye movement (REM) sleep is governed by the interaction of REM‐promoting and REM‐inhibiting nuclei in the pontomesencephalic…”
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Astroglial Glutamate Glutamine Shuttle Is Involved in Central Sensitization of Nociceptive Neurons in Rat Medullary Dorsal Horn by Chiang, Chen-Yu, Wang, Jing, Xie, Yu-Feng, Zhang, Sun, Hu, James W, Dostrovsky, Jonathan O, Sessle, Barry J

“…Growing evidence suggests that astroglia are involved in pain states, but no studies have tested their possible involvement in modulating the activity of…”
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Stimulation-induced inhibition of neuronal firing in human subthalamic nucleus by FILALI, Mohammed, HUTCHISON, William D, PALTER, Vanessa N, LOZANO, Andres M, DOSTROVSKY, Jonathan O

“…The subthalamic nucleus (STN) is an important component of the basal ganglia (BG) and plays a major role in the pathogenesis of Parkinson's disease (PD)…”
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Human Anterior Cingulate Cortex Neurons Encode Cognitive and Emotional Demands by Davis, Karen D, Taylor, Keri S, Hutchison, William D, Dostrovsky, Jonathan O, McAndrews, Mary P, Richter, Erich O, Lozano, Andres M

“…The cortical mechanisms and substrates of cognitive and emotional demands are poorly understood. Lesion studies and functional imaging implicate the anterior…”
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Synchronized Neuronal Discharge in the Basal Ganglia of Parkinsonian Patients Is Limited to Oscillatory Activity by Levy, Ron, Hutchison, William D, Lozano, Andres M, Dostrovsky, Jonathan O

“…It has been proposed that an increase in synchronization between neurons in the basal ganglia contributes to the clinical features of Parkinson's disease (PD)…”
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Activation of peripheral P2X receptors is sufficient to induce central sensitization in rat medullary dorsal horn nociceptive neurons by Cherkas, Pavel S., Dostrovsky, Jonathan O., Sessle, Barry J.

“…► ATP contributes to the development of central sensitization (CS) in medullary nociceptive neurons. ► Application of purinergic agonist to the rat tooth pulp…”
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Pallidal neuronal activity: Implications for models of dystonia by Hutchison, William D., Lang, Anthony E., Dostrovsky, Jonathan O., Lozano, Andres M.

“…Dystonia is a neurological syndrome involving sustained contractions of opposing muscles leading to abnormal movements and postures. Recent studies report…”
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Response of human thalamic neurons to high-frequency stimulation by Birdno, Merrill J, Tang, Wei, Dostrovsky, Jonathan O, Hutchison, William D, Grill, Warren M

“…Thalamic deep brain stimulation (DBS) is an effective treatment for tremor, but the mechanisms of action remain unclear. Previous studies of human thalamic…”
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Characterization of REM-sleep associated ponto-geniculo-occipital waves in the human pons by LIM, Andrew S, LOZANO, Andres M, MORO, Elena, HAMANI, Clement, HUTCHISON, William D, DOSTROVSKY, Jonathan O, LANG, Anthony E, WENNBERG, Richard A, MURRAY, Brian J

“…Ponto-geniculo-occipital (PGO) waves are phasic pontine, lateral geniculate, and cortical field potentials occurring during and before REM sleep that are…”
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Levodopa response in long-term bilateral subthalamic stimulation for Parkinson's disease by Piboolnurak, Panida, Lang, Anthony E., Lozano, Andres M., Miyasaki, Janis M., Saint-Cyr, Jean A., Poon, Yu-Yan W., Hutchison, William D., Dostrovsky, Jonathan O., Moro, Elena

“…Subthalamic nucleus deep brain stimulation (STN‐DBS) is effective in advanced Parkinson's disease (PD), but its effects on the levodopa response are unclear…”
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Systemic pregabalin attenuates facial hypersensitivity and noxious stimulus-evoked release of glutamate in medullary dorsal horn in a rodent model of trigeminal neuropathic pain by Kumar, Naresh, Cherkas, Pavel S., Varathan, Vidya, Miyamoto, Makiko, Chiang, Chen Yu, Dostrovsky, Jonathan O., Sessle, Barry J., Coderre, Terence J.

“…Pregabalin is effective in treating many neuropathic pain conditions. However, the mechanisms of its analgesic effects remain poorly understood. The aim of the…”
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