Search Results - "DONOVAN, Gerald P"
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L-SIGN (CD 209L) Is a Liver-Specific Capture Receptor for Hepatitis C Virus
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-2003)“…Hepatitis C virus (HCV) infects nearly 3% of the population of the world and is a major cause of liver disease. However, the mechanism whereby the virus…”
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Potent Antitumor Activity of an Auristatin-Conjugated, Fully Human Monoclonal Antibody to Prostate-Specific Membrane Antigen
Published in Clinical cancer research (15-04-2006)“…Prostate-specific membrane antigen (PSMA) is the prototypic cell-surface marker of prostate cancer and provides an attractive target for monoclonal antibody…”
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The Homodimer of Prostate-Specific Membrane Antigen Is a Functional Target for Cancer Therapy
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2003)“…Prostate-specific membrane antigen (PSMA) is a type 2 integral membrane glycoprotein that serves as an attractive target for cancer immunotherapy by virtue of…”
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A Novel Alphavirus Vaccine Encoding Prostate-Specific Membrane Antigen Elicits Potent Cellular and Humoral Immune Responses
Published in Clinical cancer research (01-07-2007)“…Purpose: Prostate-specific membrane antigen (PSMA) is an attractive target for active immunotherapy. Alphavirus vaccines have shown promise in eliciting…”
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Comparison of Two Cancer Vaccines Targeting Tyrosinase: Plasmid DNA and Recombinant Alphavirus Replicon Particles
Published in Clinical cancer research (15-11-2005)“…Purpose: Immunization of mice with xenogeneic DNA encoding human tyrosinase-related proteins 1 and 2 breaks tolerance to these self-antigens and leads to tumor…”
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Protection Against Clostridium difficile Infection With Broadly Neutralizing Antitoxin Monoclonal Antibodies
Published in The Journal of infectious diseases (01-09-2012)“…The spore-forming bacterium Clostridium difficile represents the principal cause of hospital-acquired diarrhea and pseudomembranous colitis worldwide. C…”
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L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles
Published in Journal of general virology (01-09-2006)“…1 Albert Einstein College of Medicine, Microbiology and Immunology Department, 1300 Morris Park Avenue, Bronx, NY 10461, USA 2 Progenics Pharmaceuticals Inc.,…”
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Expression of Unmodified Hepatitis C Virus Envelope Glycoprotein-Coding Sequences Leads to Cryptic Intron Excision and Cell Surface Expression of E1/E2 Heterodimers Comprising Full-Length and Partially Deleted E1
Published in Journal of Virology (01-12-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1
Published in Vaccine (13-08-2009)“…Abstract SOSIP gp140 trimers represent a soluble, stabilized, proteolytically cleaved form of the HIV-1 envelope (Env) glycoproteins. SOSIP gp140 derived from…”
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Epileptic seizures caused by inactivation of a novel gene, jerky , related to centromere binding protein-B in transgenic mice
Published in Nature genetics (01-09-1995)“…Epidemiological data and genetic studies indicate that certain forms of human epilepsy are inherited. Based on the similarity between the human and mouse…”
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Sensitivity to Jerky Gene Dosage Underlies Epileptic Seizures in Mice
Published in The Journal of neuroscience (15-06-1997)“…Animals with one deleted jerky allele are more susceptible to chemically induced seizures than wild-type mice and display recurrent behavioral seizures. The…”
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Expressionof Unmodified Hepatitis C Virus Envelope Glycoprotein-Coding SequencesLeads to Cryptic Intron Excision and Cell Surface Expression of E1/E2Heterodimers Comprising Full-Length and Partially DeletedE1
Published in Journal of virology (15-12-2003)“…ABSTRACT Hepatitis C virus (HCV) is a positive-strand RNA virus that replicates exclusively in the cytoplasm of infected cells. The viral envelope…”
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623 Hepatitis C virus (HCV) isolates interact with L-sign, a liver-specific capture receptor
Published in Hepatology (Baltimore, Md.) (2003)Get full text
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