Search Results - "DONGXIA GAO"

Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes by Asleh, Karama, Negri, Gian Luca, Spencer Miko, Sandra E., Colborne, Shane, Hughes, Christopher S., Wang, Xiu Q., Gao, Dongxia, Gilks, C. Blake, Chia, Stephen K. L., Nielsen, Torsten O., Morin, Gregg B.

“…Despite advances in genomic classification of breast cancer, current clinical tests and treatment decisions are commonly based on protein level information…”
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CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer by Liu, Shuzhen, Lachapelle, Jonathan, Leung, Samuel, Gao, Dongxia, Foulkes, William D, Nielsen, Torsten O

“…Tumor infiltrating lymphocytes may indicate an immune response to cancer development, but their significance remains controversial in breast cancer. We…”
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Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer by Cheang, Maggie C. U., Chia, Stephen K., Voduc, David, Gao, Dongxia, Leung, Samuel, Snider, Jacqueline, Watson, Mark, Davies, Sherri, Bernard, Philip S., Parker, Joel S., Perou, Charles M., Ellis, Matthew J., Nielsen, Torsten O.

“…Background Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer:…”
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An International Ki67 Reproducibility Study by POLLEY, Mei-Yin C, LEUNG, Samuel C. Y, GOWN, Allen M, SYMMANS, W. Fraser, PIPER, Tammy, MEHL, Erika, ENOS, Rebecca A, HAYES, Daniel F, DOWSETT, Mitch, NIELSEN, Torsten O, McSHANE, Lisa M, DONGXIA GAO, HUGH, Judith C, MASTROPASQUA, Mauro G, VIALE, Giuseppe, ZABAGLO, Lila A, PENAULT-LLORCA, Frédérique, BARTLETT, John M. S

“…In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However,…”
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Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group by Denkert, Carsten, Wienert, Stephan, Poterie, Audrey, Loibl, Sibylle, Budczies, Jan, Badve, Sunil, Bago-Horvath, Zsuzsanna, Bane, Anita, Bedri, Shahinaz, Brock, Jane, Chmielik, Ewa, Christgen, Matthias, Colpaert, Cecile, Demaria, Sandra, Van den Eynden, Gert, Floris, Giuseppe, Fox, Stephen B, Gao, Dongxia, Ingold Heppner, Barbara, Kim, S Rim, Kos, Zuzana, Kreipe, Hans H, Lakhani, Sunil R, Penault-Llorca, Frederique, Pruneri, Giancarlo, Radosevic-Robin, Nina, Rimm, David L, Schnitt, Stuart J, Sinn, Bruno V, Sinn, Peter, Sirtaine, Nicolas, O'Toole, Sandra A, Viale, Giuseppe, Van de Vijver, Koen, de Wind, Roland, von Minckwitz, Gunter, Klauschen, Frederick, Untch, Michael, Fasching, Peter A, Reimer, Toralf, Willard-Gallo, Karen, Michiels, Stefan, Loi, Sherene, Salgado, Roberto

“…Multiple independent studies have shown that tumor-infiltrating lymphocytes (TIL) are prognostic in breast cancer with potential relevance for response to…”
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Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas by Dancsok, Amanda R., Gao, Dongxia, Lee, Anna F., Steigen, Sonja Eriksson, Blay, Jean-Yves, Thomas, David M., Maki, Robert G., Nielsen, Torsten O., Demicco, Elizabeth G.

“…Early trials for immune checkpoint inhibitors in sarcomas have delivered mixed results, and efforts to improve outcomes now look to combinatorial strategies…”
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Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes by Yerushalmi, Rinat, Gelmon, Karen A., Leung, Samuel, Gao, Dongxia, Cheang, Maggie, Pollak, Michael, Turashvili, Gulisa, Gilks, Blakes C., Kennecke, Hagen

“…Insulin-like growth factor-1 receptor (IGF-1R) is expressed in normal and malignant breast tissue and has been implicated in cell survival and resistance to…”
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Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort by Cheng, Angela S., Leung, Samuel C. Y., Gao, Dongxia, Burugu, Samantha, Anurag, Meenakshi, Ellis, Matthew J., Nielsen, Torsten O.

“…Purpose Alterations to mismatch repair (MMR) pathways are a known cause of cancer, particularly colorectal and endometrial carcinomas. Recently, checkpoint…”
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An international study to increase concordance in Ki67 scoring by Polley, Mei-Yin C, Leung, Samuel C Y, Gao, Dongxia, Mastropasqua, Mauro G, Zabaglo, Lila A, Bartlett, John M S, McShane, Lisa M, Enos, Rebecca A, Badve, Sunil S, Bane, Anita L, Borgquist, Signe, Fineberg, Susan, Lin, Ming-Gang, Gown, Allen M, Grabau, Dorthe, Gutierrez, Carolina, Hugh, Judith C, Moriya, Takuya, Ohi, Yasuyo, Osborne, C Kent, Penault-Llorca, Frédérique M, Piper, Tammy, Porter, Peggy L, Sakatani, Takashi, Salgado, Roberto, Starczynski, Jane, Lænkholm, Anne-Vibeke, Viale, Giuseppe, Dowsett, Mitch, Hayes, Daniel F, Nielsen, Torsten O

“…Although an important biomarker in breast cancer, Ki67 lacks scoring standardization, which has limited its clinical use. Our previous study found variability…”
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Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types by Zhu, Mayanne M.T., Burugu, Samantha, Gao, Dongxia, Yu, Jamie, Kos, Zuzana, Leung, Samuel, Horst, Basil A., Nielsen, Torsten O.

“…Glucocorticoid-induced TNF receptor (GITR) is an emerging immunotherapy target that is expressed at high levels on regulatory T cells. Agonistic anti-GITR…”
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Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors by Milne, Katy, Köbel, Martin, Kalloger, Steven E, Barnes, Rebecca O, Gao, Dongxia, Gilks, C Blake, Watson, Peter H, Nelson, Brad H

“…Tumor-infiltrating T cells are associated with survival in epithelial ovarian cancer (EOC), but their functional status is poorly understood, especially…”
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High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy: Results from the DBCG77B Clinical Trial by Nielsen, Torsten O, Jensen, Maj-Brit, Burugu, Samantha, Gao, Dongxia, Jørgensen, Charlotte L Tykjaer, Balslev, Eva, Ejlertsen, Bent

“…Luminal A breast cancers have better prognosis than other molecular subtypes. Luminal A cancers may also be insensitive to adjuvant chemotherapy, although…”
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TIM-3 expression in breast cancer by Burugu, Samantha, Gao, Dongxia, Leung, Samuel, Chia, Stephen K., Nielsen, Torsten O.

“…Tumor-infiltrating lymphocytes (TILs) are predominantly present in breast cancer patients with estrogen receptor negative tumors, among whom increasing levels…”
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Study on micromixing and reaction process in a rotating packed bed by Jianwen, Zhang, Dongxia, Gao, Yachao, Li, Jianyun, He

“…[Display omitted] •Grid and sub-grid scale models are proposed.•Sub-grid scale model performs better.•Micromixing and reaction are influenced by the volume…”
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biological and clinical value of p53 expression in pelvic high-grade serous carcinomas by Köbel, Martin, Reuss, Alexander, Bois, Andreas du, Kommoss, Stefan, Kommoss, Friedrich, Gao, Dongxia, Kalloger, Steve E, Huntsman, David G, Gilks, C. Blake

“…Studies on the p53 expression and outcome for women with ovarian carcinoma have produced conflicting results. The observed heterogeneity may be due to the…”
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Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma by Tessier-Cloutier, Basile, Kalloger, Steve E, Al-Kandari, Mohammad, Milne, Katy, Gao, Dongxia, Nelson, Brad H, Renouf, Daniel J, Sheffield, Brandon S, Schaeffer, David F

“…Programmed cell death 1 (PD1) inhibitors have recently shown promising anti-cancer effects in a number of solid tumor types. A predictive biomarker to this…”
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A clinical calculator to predict disease outcomes in women with triple-negative breast cancer by Polley, Mei-Yin C., Leon-Ferre, Roberto A., Leung, Samuel, Cheng, Angela, Gao, Dongxia, Sinnwell, Jason, Liu, Heshan, Hillman, David W., Eyman-Casey, Abraham, Gilbert, Judith A., Negron, Vivian, Boughey, Judy C., Liu, Minetta C., Ingle, James N., Kalari, Krishna, Couch, Fergus, Carter, Jodi M., Visscher, Daniel W., Nielsen, Torsten O., Goetz, Matthew P.

“…Purpose Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, characterized by substantial risks of early disease recurrence…”
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Ultrasound-guided Microwave Ablation of Adenolymphoma of Parotid Gland: A Case Report by Xiaohui, Ji, MD, Juanjuan, Li, MD, Dongxia, Gao, MD

“…Adenolymphoma is the second most common benign parotid tumor after pleomorphic adenoma. Although microwave ablation (MWA) has been proved to be effective for…”
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A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard by Won, Jennifer R, Gao, Dongxia, Chow, Christine, Cheng, Jinjin, Lau, Sherman YH, Ellis, Matthew J, Perou, Charles M, Bernard, Philip S, Nielsen, Torsten O

“…Gene expression profiling of breast cancer delineates a particularly aggressive subtype referred to as ‘basal-like’, which comprises ∼15% of all breast…”
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Correction to: Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort by Cheng, Angela S., Leung, Samuel C. Y., Gao, Dongxia, Burugu, Samantha, Anurag, Meenakshi, Ellis, Matthew J., Nielsen, Torsten O.

“…In the original publication of the article, the funding statement was published incompletely. The corrected funding statement should read as below:…”
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