Search Results - "DONG HO WOO"

Glial Regulation of the Neuronal Connectome through Local and Long-Distant Communication by Fields, R. Douglas, Woo, Dong Ho, Basser, Peter J.

“…If “the connectome” represents a complete map of anatomical and functional connectivity in the brain, it should also include glia. Glia define and regulate…”
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GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease by Jo, Seonmi, Yarishkin, Oleg, Hwang, Yu Jin, Chun, Ye Eun, Park, Mijeong, Woo, Dong Ho, Bae, Jin Young, Kim, Taekeun, Lee, Jaekwang, Chun, Heejung, Park, Hyun Jung, Lee, Da Yong, Hong, Jinpyo, Kim, Hye Yun, Oh, Soo-Jin, Park, Seung Ju, Lee, Hyo, Yoon, Bo-Eun, Kim, YoungSoo, Jeong, Yong, Shim, Insop, Bae, Yong Chul, Cho, Jeiwon, Kowall, Neil W, Ryu, Hoon, Hwang, Eunmi, Kim, Daesoo, Lee, C Justin

“…In Alzheimer's disease, increased MAOB activity in reactive astrocytes leads to enhanced GABA release, and blockage of this pathway ameliorates memory…”
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Visual stimulation-induced mild stress enhances cognitive behavior in cynomolgus monkey by Woo, Dong Ho, Koh, Eun Ha, Shin, Seung-Hyuk, Yang, Young-Su, Choe, Jae Chun, Lee, C. Justin, Han, Su-Cheol

“…Cortisol is a well-known endogenous glucocorticoid that serves as a stress indicator. It is normally released under stressful condition to warn about imminent…”
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Regulation of myelin structure and conduction velocity by perinodal astrocytes by Dutta, Dipankar J., Woo, Dong Ho, Lee, Philip R., Pajevic, Sinisa, Bukalo, Olena, Huffman, William C., Wake, Hiroaki, Basser, Peter J., SheikhBahaei, Shahriar, Lazarevic, Vanja, Smith, Jeffrey C., Fields, R. Douglas

“…The speed of impulse transmission is critical for optimal neural circuit function, but it is unclear how the appropriate conduction velocity is established in…”
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Ultrasonic Neuromodulation via Astrocytic TRPA1 by Oh, Soo-Jin, Lee, Jung Moo, Kim, Hyun-Bum, Lee, Jungpyo, Han, Sungmin, Bae, Jin Young, Hong, Gyu-Sang, Koh, Wuhyun, Kwon, Jea, Hwang, Eun-Sang, Woo, Dong Ho, Youn, Inchan, Cho, Il-Joo, Bae, Yong Chul, Lee, Sungon, Shim, Jae Wan, Park, Ji-Ho, Lee, C. Justin

“…Low-intensity, low-frequency ultrasound (LILFU) is the next-generation, non-invasive brain stimulation technology for treating various neurological and…”
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Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons by Wake, Hiroaki, Ortiz, Fernando C., Woo, Dong Ho, Lee, Philip R., Angulo, María Cecilia, Fields, R. Douglas

“…The myelin sheath on vertebrate axons is critical for neural impulse transmission, but whether electrically active axons are preferentially myelinated by glial…”
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Establishment of Neurotoxicity Assessment Using Microelectrode Array (MEA) with hiPSC-Derived Neurons and Evaluation of New Psychoactive Substances (NPS) by Kyu-ree Kang, C-Yoon Kim, Jin Kim, Bokyeong Ryu, Seul-Gi Lee, Jieun Baek, Ye-Ji Kim, Jin-Moo Lee, Yootmo Lee, Sun-Ok Choi, Dong Ho Woo, Il Hwan Park, Hyung Min Chung

“…Background and Objectives: Currently, safety pharmacological tests for the central nervous system depend on animal behavioral analysis. However, due to the…”
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TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation by Woo, Dong Ho, Han, Kyung-Seok, Shim, Jae Wan, Yoon, Bo-Eun, Kim, Eunju, Bae, Jin Young, Oh, Soo-Jin, Hwang, Eun Mi, Marmorstein, Alan D, Bae, Yong Chul, Park, Jae-Yong, Lee, C. Justin

“…Astrocytes release glutamate upon activation of various GPCRs to exert important roles in synaptic functions. However, the molecular mechanism of release has…”
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A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes by Mi Hwang, Eun, Kim, Eunju, Yarishkin, Oleg, Ho Woo, Dong, Han, Kyung-Seok, Park, Nammi, Bae, Yeonju, Woo, Junsung, Kim, Donggyu, Park, Myeongki, Lee, C. Justin, Park, Jae-Yong

“…TWIK-1 is a member of the two-pore domain K + (K2P) channel family that plays an essential part in the regulation of resting membrane potential and cellular…”
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The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1 by Shin, Hye Won, Soh, Jeong Seop, Kim, Hee Zoo, Hong, Jinpyo, Woo, Dong Ho, Heo, Jun Young, Hwang, Eun Mi, Park, Jae-Yong, Lee, C. Justin

“…Purpose Bupivacaine, levobupivacaine, and ropivacaine are amide local anesthetics. Levobupivacaine and ropivacaine are stereoisomers of bupivacaine and were…”
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Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson’s Disease by Heo, Jun Young, Nam, Min-Ho, Yoon, Hyung Ho, Kim, Jeongyeon, Hwang, Yu Jin, Won, Woojin, Woo, Dong Ho, Lee, Ji Ae, Park, Hyun-Jung, Jo, Seonmi, Lee, Min Joung, Kim, Sunpil, Shim, Jeong-Eun, Jang, Dong-Pyo, Kim, Kyoung I., Huh, Sue H., Jeong, Jae Y., Kowall, Neil W., Lee, Junghee, Im, Hyeonjoo, Park, Jong Hyun, Jang, Bo Ko, Park, Ki Duk, Lee, Hyunjoo J., Shin, Hyogeun, Cho, Il-Joo, Hwang, Eun Mi, Kim, YoungSoo, Kim, Hye Yun, Oh, Soo-Jin, Lee, Seung Eun, Paek, Sun Ha, Yoon, Jong Hyuk, Jin, Byung K., Kweon, Gi Ryang, Shim, Insop, Hwang, Onyou, Ryu, Hoon, Jeon, Sang Ryong, Lee, C. Justin

“…Current pharmacological treatments for Parkinson’s disease (PD) are focused on symptomatic relief, but not on disease modification, based on the strong belief…”
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Synthetic ShK-like Peptide from the Jellyfish Nemopilema nomurai Has Human Voltage-Gated Potassium-Channel-Blocking Activity by Kim, Ye-Ji, Jo, Yejin, Lee, Seung Eun, Kim, Jungeun, Choi, Jae-Pil, Lee, Nayoung, Won, Hyokyoung, Woo, Dong Ho, Yum, Seungshic

“…We identified a new human voltage-gated potassium channel blocker, NnK-1, in the jellyfish based on its genomic information. The gene sequence encoding NnK-1…”
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Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer’s disease by Park, Sohui, Kim, Hye Yun, Oh, Hyun-A, Shin, Jisu, Park, In Wook, Yoon, Soljee, Woo, Dong Ho, Kim, YoungSoo

“…Alzheimer’s disease (AD) is the most common type of dementia characterized by the abnormal accumulation of amyloid-β (Aβ) in the brain. Aβ misfolding is…”
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Dopamine-modified hyaluronic acid (DA-HA) as a novel dopamine-mimetics with minimal autoxidation and cytotoxicity by Kim, Sunpil, Kim, Ye-Ji, Park, Kyoung Hwan, Huh, Kang Moo, Kang, Sun-Woong, Lee, C. Justin, Woo, Dong Ho

“…Dopamine-modified hyaluronic acid (DA-HA) has been initially developed as an efficient coating and adhesion material for industrial uses. However, the…”
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Corrigendum to “Dopamine-modified hyaluronic acid (DA-HA) as a novel dopamine-mimetics with minimal autoxidation and cytotoxicity” [Redox Biol. 76 (2024) 103320] by Kim, Sunpil, Kim, Ye-Ji, Park, Kyoung Hwan, Huh, Kang Moo, Kang, Sun-Woong, Lee, C. Justin, Woo, Dong Ho

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Classification of advanced methods for evaluating neurotoxicity by Han, Kyung-Seok, Woo, Dong Ho

“…Purpose of review As fields such as neurotoxicity evaluation and neuro-related drug research are increasing in popularity, there is a demand for the expansion…”
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Astrocytic control of synaptic NMDA receptors by Lee, C. Justin, Mannaioni, Guido, Yuan, Hongjie, Woo, Dong Ho, Gingrich, Melissa B., Traynelis, Stephen F.

“…Astrocytes express a wide range of G-protein coupled receptors that trigger release of intracellular Ca 2+ , including P2Y, bradykinin and protease activated…”
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An Octopus-Derived Peptide with Antidiuretic Activity in Rats by Kim, Ye-Ji, Lee, Jei Ha, Jung, Seung-Hyun, Kim, Ki Hyun, Choi, Chang-Hoon, Jo, Seonmi, Woo, Dong Ho

“…Discovering new drug candidates with high efficacy and few side effects is a major challenge in new drug development. The two evolutionarily related peptides…”
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Activation of Astrocytic μ-opioid Receptor Elicits Fast Glutamate Release Through TREK-1-Containing K2P Channel in Hippocampal Astrocytes by Woo, Dong Ho, Bae, Jin Young, Nam, Min-Ho, An, Heeyoung, Ju, Yeon Ha, Won, Joungha, Choi, Jae Hyouk, Hwang, Eun Mi, Han, Kyung-Seok, Bae, Yong Chul, Lee, C Justin

“…Recently, μ-opioid receptor (MOR), one of the well-known Gi-protein coupled receptors (Gi-GPCR), was reported to be highly expressed in the hippocampal…”
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Anti-stress Effect of Octopus Cephalotocin in Rats by Kim, Ye-Ji, Jo, Seonmi, Jung, Seung-Hyun, Woo, Dong Ho

“…Cephalotocin is a bioactivity-regulating peptide expressed in octopus ( Octopus vulgaris ). The peptide sequence of cephalotocin is very similar to the peptide…”
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