Search Results - "DONE, S. J"

Acquisition of metastatic tissue from patients with bone metastases from breast cancer by Hilton, J. F., Amir, E., Hopkins, S., Nabavi, M., DiPrimio, G., Sheikh, A., Done, S. J., Gianfelice, D., Kanji, F., Dent, S., Barth, D., Bouganim, N., Al-Najjar, A., Clemons, M.

“…Biopsies of metastatic tissue are increasingly being performed. Bone is the most frequent site of metastasis in breast cancer patients, but bone remains…”
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Mechanisms and pathways of bone metastasis: challenges and pitfalls of performing molecular research on patient samples by Cawthorn, T. R, Amir, E, Broom, R, Freedman, O, Gianfelice, D, Barth, D, Wang, D, Holen, I, Done, S. J, Clemons, M

“…The molecular mechanisms underlying the development of bone metastases in breast cancer remain unclear. Disseminated tumour cells (DTCs) in the bone marrow of…”
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Limited tissue fixation times and whole genomic amplification do not impact array CGH profiles by Ghazani, A A, Arneson, N C R, Warren, K, Done, S J

“…Background: Array comparative genomic hybridisation (CGH) is a powerful method for the genetic analysis of lesional and normal tissues to identify genomic…”
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Role of Nek2 on centrosome duplication and aneuploidy in breast cancer cells by Cappello, P, Blaser, H, Gorrini, C, Lin, D C C, Elia, A J, Wakeham, A, Haider, S, Boutros, P C, Mason, J M, Miller, N A, Youngson, B, Done, S J, Mak, T W

“…Breast cancer is the most common solid tumor and the second most common cause of death in women. Despite a large body of literature and progress in breast…”
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Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations by Phillips, K A, Nichol, K, Ozcelik, H, Knight, J, Done, S J, Goodwin, P J, Andrulis, I L

“…Breast carcinomas occurring in carriers of BRCA1 gene mutations may have a distinctly different pathway of molecular pathogenesis from those occurring in…”
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p53 Missense Mutations in Microdissected High-Grade Ductal Carcinoma In Situ of the Breast by Done, Susan J., Eskandarian, Sasha, Bull, Shelley, Redston, Mark, Andrulis, Irene L.

“…Background: To understand the role of sporadic mutations in the tumor suppressor gene p53 (also known as TP53) in the pathogenesis of breast cancer, it is…”
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Mitochondrial D310 mutations in the early development of breast cancer by Xu, C, Tran-Thanh, D, Ma, C, May, K, Jung, J, Vecchiarelli, J, Done, S J

“…Background: The role of mitochondrial DNA (mtDNA) mutations in the development of breast cancer is largely unknown. In this study, we investigated the…”
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Age at diagnosis predicts local recurrence in women treated with breast-conserving surgery and postoperative radiation therapy for ductal carcinoma in situ: a population-based outcomes analysis by Kong, I, Narod, S A, Taylor, C, Paszat, L, Saskin, R, Nofech-Moses, S, Thiruchelvam, D, Hanna, W, Pignol, J P, Sengupta, S, Elavathil, L, Jani, P A, Done, S J, Metcalfe, S, Rakovitch, E

“…The main goal of treating ductal carcinoma in situ (dcis) is to prevent the development of invasive breast cancer. Most women are treated with…”
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Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer by KHOO, U.-S, OZCELIK, H, POON, C. S, LEUNG, Y.-F, LOONG, F, IP, P, CHAN, G. S, ANDRULIS, I. L, LU, J, HO, F. C. S, CHEUNG, A. N. Y, CHOW, L. W. C, NGAN, H. Y. S, DONE, S. J, LIANG, A, CHAN, V. W, AU, G. K, NG, W.-F

“…Inherited mutations in the BRCA1 gene confer increased susceptibility to breast and ovarian cancer. Its role in sporadic carcinogenesis is not well defined…”
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p53 mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias by DONE, S. J, ARNESON, N. C. R, ÖZCELIK, H, REDSTON, M, ANDRULIS, I. L

“…The development and progression of human breast neoplasia is characterized by the accumulation of numerous somatic genetic alterations. Although mutation of…”
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Analysis of mRNA from Microdissected Frozen Tissue Sections without RNA Isolation by To, Minh D., Done, Susan J., Redston, Mark, Andrulis, Irene L.

“…Molecular study of gene expression in solid tumors is based largely on mRNA extracted from crushed frozen tumor samples. As most tumors are heterogeneous in…”
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The Quasi-Biennial Oscillation and Ross River virus incidence in Queensland, Australia by Done, Sinead J, Holbrook, Neil J, Beggs, Paul J

“…Ross River virus (RRV) is the most important vector-borne disease in Australia. The National Notifiable Diseases Surveillance System has confirmed that its…”
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Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride by Hart, D A, Done, S J, Benediktsson, H, Lenz, S P

“…Previous investigations have indicated that initiation of LiCl treatment (4 mg/day) of female NZB/W mice at 10 weeks of age led to enhanced survival of 50% of…”
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p53 protein accumulation in non-invasive lesions surrounding p53 mutation positive invasive breast cancers by DONE, Susan J, ARNESON, Nona C. R, ÖZCELIK, Hilmi, REDSTON, Mark, ANDRULIS, Irene L

“…p53 mutation is a common event in sporadic breast cancer being found in 15-50% of invasive carcinomas. The purpose of this study was to determine the earliest…”
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Mitochondrial D3 10 mutations in the early development of breast cancer by XU, C, TRAN-THANH, D, MA, C, MAY, K, JUNG, J, VECCHIARELLI, J, DONE, S. J

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Abstract P2-12-15: ReFilx- synthetic biodegradable soft tissue fillers for breast conserving surgery in breast cancer by Leong, WL, Sharifpoor, S, Battiston, K, Charleton, D, Corrigan, M, McCready, DR, Done, SJ, Santerre, JP

“…Introduction: Breast conserving surgery (BCS) is the most common procedure performed in breast cancers, but it can often result in breast deformities that can…”
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Gene expression differences between disseminated tumor cells and tumor cells from overt bone metastases in patients with metastatic breast cancer by Broom, R. J., Amir, E., Cawthorn, T., Freedman, O., Gianfelice, D., Barth, D., Galica, J., Wang, D., Done, S. J., Clemons, M.

“…Abstract only 1040 Background: Despite extensive work evaluating molecular differences between primary tumors, circulating tumor cells, disseminated tumor…”
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Abstract P2-12-02: Is breast-conserving therapy effective in women with large ductal carcinoma in situ (DCIS) lesions? A population-based analysis by Lalani, N, Paszat, L, Nofech-Mozes, S, Sutradhar, R, Gu, S, Hanna, W, Fong, C, Miller, N, Youngson, B, Done, SJ, Tuck, A, Chang, MC, Sengupta, S, Jani, PA, Bonin, M, Rakovitch, E

“…Background: Most women diagnosed with DCIS will be treated by breast-conserving surgery (BCS) with or without radiotherapy (RT). Data on outcomes following…”
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Abstract P4-15-05: The presence of one or multiple foci of microinvasion is not associated with an increased risk of local recurrence in women with ductal carcinoma in situ treated with breast conserving therapy by Lalani, N, Paszat, L, Sutradhar, R, Gu, S, Fong, C, Nofech-Mozes, S, Hanna, W, Tuck, A, Youngson, B, Miller, N, Done, SJ, Chang, MC, Sengupta, S, Elavathil, L, Jani, PA, Bonin, M, Rakovitch, E

“…Background: Ductal Carcinoma in Situ (DCIS) is a non-invasive breast cancer often treated with breast-conserving surgery (BCS) with or without radiotherapy…”
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Telomere Length on Chromosome 17q Shortens More than Global Telomere Length in the Development of Breast Cancer by Rashid-Kolvear, Fariborz, Pintiliet, Melania, Done, Susan J.

“…It is known that total telomere length is shorter in invasive breast cancer than in normal breast tissue but the status of individual telomere lengths has not…”
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