Search Results - "DONALDSON, Peter T"

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury by Donaldson, Peter T, Daly, Ann K, Henderson, Jill, Graham, Julia, Pirmohamed, Munir, Bernal, William, Day, Christopher P, Aithal, Guruprasad P

“…Background & Aims Co-amoxiclav is one of the most common causes of drug-induced liver injury (DILI). Although there are previous reports of genetic…”
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Genomic Polymorphism at the Interferon-Induced Helicase (IFIH1) Locus Contributes to Graves’ Disease Susceptibility by Sutherland, Alison, Davies, Jocelyn, Owen, Catherine J., Vaikkakara, Suresh, Walker, Christine, Cheetham, Timothy D., James, R. Andrew, Perros, Petros, Donaldson, Peter T., Cordell, Heather J., Quinton, Richard, Pearce, Simon H. S.

“…Context: A recent large-scale analysis of nonsynonymous coding polymorphisms showed strong evidence that an alanine to threonine amino acid change at codon 946…”
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Long-Term Outcome of Hepatitis C Infection after Liver Transplantation by Gane, Edward J, Portmann, Bernard C, Naoumov, Nikolai V, Smith, Heather M, Underhill, James A, Donaldson, Peter T, Maertens, Geert, Williams, Roger

“…Cirrhosis related to infection with the hepatitis C virus (HCV) is a common reason for liver transplantation, although viremia is known to persist in over 95…”
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Clinical distinctions and pathogenic implications of type 1 autoimmune hepatitis in Brazil and the United States by CZAJA, Albert J, SOUTO, Enrico O, BITTENCOURT, Paulo L, CANCADO, Eduardo L. R, PORTA, Gilda, GOLDBERG, Anna Carla, DONALDSON, Peter T

“…Type 1 autoimmune hepatitis has a strong genetic predisposition that varies among different ethnic groups. Our aims were to determine if the clinical…”
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Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles by Lucena, M. Isabel, Molokhia, Mariam, Shen, Yufeng, Urban, Thomas J, Aithal, Guruprasad P, Andrade, Raúl J, Day, Christopher P, Ruiz–Cabello, Francisco, Donaldson, Peter T, Stephens, Camilla, Pirmohamed, Munir, Romero–Gomez, Manuel, Navarro, Jose Maria, Fontana, Robert J, Miller, Michael, Groome, Max, Bondon–Guitton, Emmanuelle, Conforti, Anita, Stricker, Bruno H.C, Carvajal, Alfonso, Ibanez, Luisa, Yue, Qun–Ying, Eichelbaum, Michel, Floratos, Aris, Pe'er, Itsik, Daly, Mark J, Goldstein, David B, Dillon, John F, Nelson, Matthew R, Watkins, Paul B, Daly, Ann K

“…Background & Aims Drug-induced liver injury (DILI), especially from antimicrobial agents, is an important cause of serious liver disease…”
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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis by Mells, George F, Floyd, James A B, Morley, Katherine I, Cordell, Heather J, Franklin, Christopher S, Shin, So-Youn, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T, Day, Darren B, Ducker, Samantha J, Muriithi, Agnes W, Wheater, Elizabeth F, Hammond, Christopher J, Dawwas, Muhammad F, Jones, David E, Peltonen, Leena, Alexander, Graeme J, Sandford, Richard N, Anderson, Carl A

“…Carl Anderson and colleagues report a genome-wide association study identifying 13 new susceptibility loci for primary biliary cirrhosis, a chronic autoimmune…”
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Electrostatic modifications of the human leukocyte antigen DR P9 peptide‐binding pocket in primary sclerosing cholangitis: Back to the future with human leukocyte antigen DRβ by Donaldson, Peter T.

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Autoimmune hepatitis/sclerosing cholangitis overlap syndrome in childhood: A 16-year prospective study by Gregorio, Germana V., Portmann, Bernard, Karani, John, Harrison, Phil, Donaldson, Peter T., Vergani, Diego, Mieli-Vergani, Giorgina

“…To investigate whether sclerosing cholangitis with an autoimmune serology characteristic of autoimmune hepatitis (AIH) and AIH are distinct entities, we…”
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HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: A large‐scale study by Donaldson, Peter T., Baragiotta, Anna, Heneghan, Michael A., Floreani, Annarosa, Venturi, Carla, Underhill, James A., Jones, David E.J., James, Oliver F.W., Bassendine, Margaret F.

“…Twin and family studies suggest there is a significant genetic component to primary biliary cirrhosis (PBC). However, the inability to replicate reported…”
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HLA-B5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin by Dillon, John F, Donaldson, Peter T, Bernal, William, Bhatnagar, Pallav, Graham, Julia, Floratos, Aris, Aithal, Guruprasad P, Nelson, Matthew R, Shen, Yufeng, John, Sally, Day, Christopher P, Daly, Ann K, Daly, Mark J, Park, B Kevin, Goldstein, David B, Pirmohamed, Munir, Pe'er, Itsik, Cordell, Heather J

“…Drug-induced liver injury (DILI) is an important cause of serious liver disease. The antimicrobial agent flucloxacillin is a common cause of DILI, but the…”
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Genetics in autoimmune hepatitis by Donaldson, Peter T

“…Current hypotheses suggest that autoimmune hepatitis (AIH) is triggered by an environmental factor in a genetically susceptible host. Multiple genes may…”
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Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis by Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A

“…Carl Anderson and colleagues report dense genotyping, using the Immunochip array, of 2,861 primary biliary cirrhosis (PBC) cases and 8,514 controls. They…”
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Gender effects and synergisms with histocompatibility leukocyte antigens in type 1 autoimmune hepatitis by Czaja, Albert J, Donaldson, Peter T

“…Our goals were to determine the effect of gender on the clinical features and treatment outcome of type 1 autoimmune hepatitis, and to assess synergisms with…”
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Gender effects and synergisms with histocompatibility leukocyte antigens in type 1 autoimmune hepatitis by Czaja, Albert J, Donaldson, Peter T

“…OBJECTIVES: Our goals were to determine the effect of gender on the clinical features and treatment outcome of type 1 autoimmune hepatitis, and to assess…”
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Antibodies to soluble liver antigen/liver pancreas and HLA risk factors for type 1 autoimmune hepatitis by Czaja, Albert J, Donaldson, Peter T, Lohse, Ansgar W

“…OBJECTIVE: Antibodies to soluble liver antigen/liver-pancreas are highly specific markers of type 1 autoimmune hepatitis that have been associated with…”
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Genetics of autoimmune and viral liver diseases; understanding the issues by Donaldson, Peter T.

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Genetic factors in the pathogenesis of primary biliary cirrhosis by Jones, David E J, Donaldson, Peter T

“…Current knowledge of the genetic basis of PBC is at best incomplete and at worst poor. Studies so far may be used as a guide to the pitfalls that await unwary…”
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De-novo autoimmune hepatitis after liver transplantation by Kerkar, Nanda, Hadzic, Nedim, Davies, Edward T, Portmann, Bernard, Donaldson, Peter T, Rela, Mohamed, Heaton, Nigel D, Vergani, Diego, Mieli-Vergani, Giorgina

“…Late graft dysfunction that does not result from recognised causes, such as rejection, infection, or vascular or biliary complications, can occur after liver…”
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Antibodies to soluble liver antigen liver pancreas and HLA risk factors for type 1 autoimmune hepatitis by Czaja, Albert J, Donaldson, Peter T, Lohse, Ansgar W

“…Antibodies to soluble liver antigen/liver-pancreas are highly specific markers of type 1 autoimmune hepatitis that have been associated with relapse. Our aim…”
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Genetic bases of autoimmune hepatitis by CZAJA, Albert J, DOHERTY, Derek G, DONALDSON, Peter T

“…Our goal was to review the hypotheses in evolution that promise to elucidate the genetic bases of autoimmune hepatitis. DRB1*0301 and DRB1*0401 are the…”
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