Search Results - "DONALDSON, Eric"

A decade after SARS: strategies for controlling emerging coronaviruses by Graham, Rachel L., Donaldson, Eric F., Baric, Ralph S.

“…Key Points Two highly pathogenic human coronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus…”
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Immunogenetic mechanisms driving norovirus GII.4 antigenic variation by Lindesmith, Lisa C, Beltramello, Martina, Donaldson, Eric F, Corti, Davide, Swanstrom, Jesica, Debbink, Kari, Lanzavecchia, Antonio, Baric, Ralph S

“…Noroviruses are the principal cause of epidemic gastroenteritis worldwide with GII.4 strains accounting for 80% of infections. The major capsid protein of…”
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A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence by Menachery, Vineet D, Yount, Boyd L, Debbink, Kari, Agnihothram, Sudhakar, Gralinski, Lisa E, Plante, Jessica A, Graham, Rachel L, Scobey, Trevor, Ge, Xing-Yi, Donaldson, Eric F, Randell, Scott H, Lanzavecchia, Antonio, Marasco, Wayne A, Shi, Zhengli-Li, Baric, Ralph S

“…Ralph Baric, Vineet Menachery and colleagues characterize a SARS-like coronavirus circulating in Chinese horseshoe bats to determine its potential to infect…”
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Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir by Donaldson, Eric F., Harrington, Patrick R., O'Rear, Julian J., Naeger, Lisa K.

“…Sofosbuvir (Sovaldi, SOF) is a nucleotide analog prodrug that targets the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase and inhibits viral…”
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Norovirus immunity and the great escape by Debbink, Kari, Lindesmith, Lisa C, Donaldson, Eric F, Baric, Ralph S

“…Funding: This work was supported by grant AI056351 from the National Institutes of Health, National Institute of Allergy and Infectious Diseases (to RSB), and…”
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Mechanisms of GII.4 norovirus persistence in human populations by Lindesmith, Lisa C, Donaldson, Eric F, Lobue, Anna D, Cannon, Jennifer L, Zheng, Du-Ping, Vinje, Jan, Baric, Ralph S

“…Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military, cruise ships,…”
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Fate and redistribution of perfluoroalkyl acids through AFFF-impacted groundwater by Bräunig, Jennifer, Baduel, Christine, Heffernan, Amy, Rotander, Anna, Donaldson, Eric, Mueller, Jochen F.

“…Leaching of perfluoroalkyl acids (PFAAs) from a local point source, a fire-fighting training area, has led to extensive contamination of a groundwater aquifer…”
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Norovirus GII.4 Strain Antigenic Variation by LINDESMITH, Lisa C, DONALDSON, Eric F, BARIC, Ralph S

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Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63 by HUYNH, Jeremy, SHIMENA LI, FRIEMAN, Matthew B, BARIC, Ralph S, DONALDSON, Eric F, YOUNT, Boyd, SMITH, Alexander, STURGES, Leslie, OLSEN, John C, NAGEL, Juliet, JOHNSON, Joshua B, AGNIHOTHRAM, Sudhakar, GATES, J. Edward

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Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus by Scobey, Trevor, Yount, Boyd L., Sims, Amy C., Donaldson, Eric F., Agnihothram, Sudhakar S., Menachery, Vineet D., Graham, Rachel L., Swanstrom, Jesica, Bove, Peter F., Kim, Jeeho D., Grego, Sonia, Randell, Scott H., Baric, Ralph S.

“…Severe acute respiratory syndrome with high mortality rates (∼50%) is associated with a novel group 2c betacoronavirus designated Middle East respiratory…”
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Surgeons respond to growing evidence by performing less knee arthroscopic surgery in older patients by Donaldson, Eric T., Doma, Kenji, Parkinson, Ben

“…Recent research has shown that knee arthroscopy does not provide a meaningful clinical benefit for degenerative knee changes in the older population. The 2016…”
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Genetic Mapping of a Highly Variable Norovirus GII.4 Blockade Epitope: Potential Role in Escape from Human Herd Immunity by DEBBINK, Kari, DONALDSON, Eric F, LINDESMITH, Lisa C, BARIC, Ralph S

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Immunological biomarker discovery in cure regimens for chronic hepatitis B virus infection by Gehring, Adam J., Mendez, Patricia, Richter, Kirsten, Ertl, Hildegund, Donaldson, Eric F., Mishra, Poonam, Maini, Mala, Boonstra, Andre, Lauer, Georg, de Creus, An, Whitaker, Kathleen, Martinez, Sara Ferrando, Weber, Jessica, Gainor, Emily, Miller, Veronica

“…There have been unprecedented advances in the identification of new treatment targets for chronic hepatitis B that are being developed with the goal of…”
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Emergence of a Norovirus GII.4 Strain Correlates with Changes in Evolving Blockade Epitopes by Lindesmith, Lisa C, Costantini, Verónica, Swanstrom, Jesica, Debbink, Kari, Donaldson, Eric F, Vinjé, Jan, Baric, Ralph S

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Coronaviruses: An RNA proofreading machine regulates replication fidelity and diversity by Denison, Mark R., Graham, Rachel L., Donaldson, Eric F., Eckerle, Lance D., Baric, Ralph S.

“…In order to survive and propagate, RNA viruses must achieve a balance between the capacity for adaptation to new environmental conditions or host cells with…”
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Emergence of New Pandemic GII.4 Sydney Norovirus Strain Correlates With Escape From Herd Immunity by Debbink, Kari, Lindesmith, Lisa C., Donaldson, Eric F., Costantini, Veronica, Beltramello, Martina, Corti, Davide, Swanstrom, Jesica, Lanzavecchia, Antonio, Vinjé, Jan, Baric, Ralph S.

“…Background. GII.4 noroviruses are a significant source of acute gastroenteritis worldwide, causing the majority of human norovirus outbreaks. Evolution of the…”
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Metagenomic Analysis of the Viromes of Three North American Bat Species: Viral Diversity among Different Bat Species That Share a Common Habitat by DONALDSON, Eric F, HASKEW, Aimee N, GATES, J. Edward, HUYNH, Jeremy, MOORE, Clea J, FRIEMAN, Matthew B

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Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations by Donaldson, Eric F., Lindesmith, Lisa C., Lobue, Anna D., Baric, Ralph S.

“…Noroviruses are important human pathogens known to cause epidemic outbreaks of severe gastroenteritis in communities, military barracks, cruise ships,…”
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Natural strain variation and antibody neutralization of dengue serotype 3 viruses by Wahala, Wahala M P B, Donaldson, Eric F, de Alwis, Ruklanthi, Accavitti-Loper, Mary Ann, Baric, Ralph S, de Silva, Aravinda M

“…Dengue viruses (DENVs) are emerging, mosquito-borne flaviviruses which cause dengue fever and dengue hemorrhagic fever. The DENV complex consists of 4…”
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Impact of hepatitis C virus polymorphisms on direct‐acting antiviral treatment efficacy: Regulatory analyses and perspectives by Harrington, Patrick R., Komatsu, Takashi E., Deming, Damon J., Donaldson, Eric F., O'Rear, Julian J., Naeger, Lisa K.

“…Several highly effective, interferon‐free, direct‐acting antiviral (DAA)‐based regimens are available for the treatment of chronic hepatitis C virus (HCV)…”
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