Search Results - "DONADI, Eduardo A"
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Transcriptional and Posttranscriptional Regulations of the HLA-G Gene
Published in Journal of immunology research (01-01-2014)“…HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-G coding region has been maintained during the evolution process, in…”
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Structural Characterization of the Interaction of Hypoxia Inducible Factor-1 with Its Hypoxia Responsive Element at the -964G > A Variation Site of the HLA-G Promoter Region
Published in International journal of molecular sciences (02-12-2021)“…Human Antigen Leukocyte-G ( ) gene encodes an immune checkpoint molecule that has restricted tissue expression in physiological conditions; however, the gene…”
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Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population
Published in PloS one (25-10-2013)“…HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher…”
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Editorial: Structural modeling and computational analyses of immune system molecules
Published in Frontiers in immunology (05-09-2023)Get full text
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Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus
Published in Autoimmunity (Chur, Switzerland) (01-06-2012)“…Recent findings provide evidence of inflammasome critical role in the predisposition to autoimmune disorders. The involvement of inflammasome in the…”
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Haplotypes of the HLA-G 3' Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially
Published in PloS one (03-01-2017)“…The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in cancer invasion and acceptance of allografts. The 5' and 3' regulatory…”
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Insights into HLA-G Genetics Provided by Worldwide Haplotype Diversity
Published in Frontiers in immunology (06-10-2014)“…Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I genes, located within the major histocompatibility complex (MHC). HLA-G…”
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IgG and IgM responses to the Plasmodium falciparum asexual stage antigens reflect respectively protection against malaria during pregnancy and infanthood
Published in Malaria journal (19-05-2024)“…Plasmodium falciparum malaria is a public health issue mostly seen in tropical countries. Until now, there is no effective malaria vaccine against antigens…”
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The single-cell transcriptome of mTECs and CD4 + thymocytes under adhesion revealed heterogeneity of mTECs and a network controlled by Aire and lncRNAs
Published in Frontiers in immunology (26-08-2024)“…To further understand the impact of deficiency of the autoimmune regulator ( ) gene during the adhesion of medullary thymic epithelial cells (mTECs) to…”
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The AIRE G228W mutation disturbs the interaction of AIRE with its partner molecule SIRT1
Published in Frontiers in immunology (06-09-2022)“…The autoimmune regulator (AIRE) protein functions as a tetramer, interacting with partner proteins to form the “AIRE complex,” which relieves RNA Pol II…”
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Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients
Published in BMC research notes (26-11-2013)“…Regardless the regulatory function of microRNAs (miRNA), their differential expression pattern has been used to define miRNA signatures and to disclose disease…”
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BRAF, TERT and HLA-G Status in the Papillary Thyroid Carcinoma: A Clinicopathological Association Study
Published in International journal of molecular sciences (01-08-2023)“…As BRAF, TERT, HLA-G, and microRNAs have been individually associated with papillary thyroid carcinoma (PTC), we aimed to evaluate the individual and…”
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Structural Modeling and Molecular Dynamics of the Immune Checkpoint Molecule HLA-G
Published in Frontiers in immunology (06-11-2020)“…HLA-G is considered to be an immune checkpoint molecule, a function that is closely linked to the structure and dynamics of the different HLA-G isoforms…”
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High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders
Published in PloS one (30-09-2020)“…Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between…”
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HLA-G Gene Variability Is Associated with Papillary Thyroid Carcinoma Morbidity and the HLA-G Protein Profile
Published in International journal of molecular sciences (16-08-2023)“…Human leukocyte antigen (HLA)-G is an immune checkpoint molecule that is highly expressed in papillary thyroid carcinoma (PTC). The HLA-G gene presents several…”
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Soluble human leukocyte antigen -G during pregnancy and infancy in Benin: Mother/child resemblance and association with the risk of malaria infection and low birth weight
Published in PloS one (06-02-2017)“…Human leukocyte antigen (HLA) G is a tolerogenic molecule involved in the maternal-fetal immune tolerance phenomenon. Its expression during some infectious…”
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Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy
Published in Frontiers in immunology (12-07-2022)“…BackgroundPlacental malaria (PM) is associated with a higher susceptibility of infants to Plasmodium falciparum (Pf) malaria. A hypothesis of immune tolerance…”
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Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice
Published in PloS one (25-11-2015)“…In autoimmune type 1 diabetes mellitus (T1D), auto-reactive clones of CD4+ and CD8+ T lymphocytes in the periphery evolve into pancreas-infiltrating T…”
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The association of HLA-G polymorphisms and the synergistic effect of sMICA and sHLA-G with chronic kidney disease and allograft acceptance
Published in PloS one (22-02-2019)“…The HLA-G and MICA genes are stimulated under inflammatory conditions and code for soluble (sMICA and sHLA-G) or membrane-bound molecules that exhibit…”
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Biological predictors shared by dementia and bullous pemphigoid patients point out a cross-antigenicity between BP180/BP230 brain and skin isoforms
Published in Immunologic research (01-10-2018)“…Bullous pemphigoid (BP) following dementia diagnosis has been reported in the elderly. Skin and brain tissues express BP180 and BP230 isoforms. Dementia has…”
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