Search Results - "DOLPH, P. J"
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Reversible symptoms and clearance of mutant prion protein in an inducible model of a genetic prion disease in Drosophila melanogaster
Published in Neurobiology of disease (01-07-2014)“…Abstract Prion diseases are progressive disorders that affect the central nervous system leading to memory loss, personality changes, ataxia and…”
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Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo
Published in Science (American Association for the Advancement of Science) (25-06-1993)“…Arrestins have been implicated in the regulation of many G protein-coupled receptor signaling cascades. Mutations in two Drosophila photoreceptor-specific…”
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Cell-autonomous requirement for DNaseII in nonapoptotic cell death
Published in Cell death and differentiation (01-10-2009)“…DNA fragmentation is a critical component of apoptosis but it has not been characterized in nonapoptotic forms of cell death, such as necrosis and autophagic…”
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The Formation of Stable Rhodopsin-Arrestin Complexes Induces Apoptosis and Photoreceptor Cell Degeneration
Published in Neuron (Cambridge, Mass.) (01-10-2000)“…Although many different mutations in humans and Drosophila cause retinal degeneration, in most cases, a molecular mechanism for the degeneration has not been…”
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Characterization of a gene cluster for exopolysaccharide biosynthesis and virulence in Erwinia stewartii
Published in Journal of Bacteriology (01-02-1988)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The adenovirus tripartite leader may eliminate the requirement for cap-binding protein complex during translation initiation
Published in Journal of Virology (01-06-1988)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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eye-specific G beta subunit essential for termination of the phototransduction cascade
Published in Nature (London) (07-07-1994)“…Heterotrimeric G proteins couple various receptors to intracellular effector molecules. Although the role of the G alpha subunit in effector activation,…”
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Translation by the adenovirus tripartite leader: elements which determine independence from cap-binding protein complex
Published in Journal of Virology (01-06-1990)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Control of extracellular polysaccharide synthesis in Erwinia stewartii and Escherichia coli K-12: a common regulatory function
Published in Journal of Bacteriology (01-10-1987)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Secondary Structure Analysis of Adenovirus Tripartite Leader
Published in The Journal of biological chemistry (25-06-1989)“…RNA secondary structure analysis was performed to understand the translation function of the adenovirus tripartite leader, a 200-nucleotide 5′ noncoding region…”
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role for the light-dependent phosphorylation of visual arrestin
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-1999)“…Arrestins are regulalory proteins that participate in the termination of G protein-mediated signal transduction. The major arrestin in the Drosophila visual…”
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Post‐transcriptional suppression of pathogenic prion protein expression in Drosophila neurons
Published in Journal of neurochemistry (01-06-2003)“…A wealth of evidence supports the view that conformational change of the prion protein, PrPC, into a pathogenic isoform, PrPSc, is the hallmark of sporadic,…”
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Molecular cloning of the pawn locus from Drosophila melanogaster
Published in Gene (22-05-2003)“…Alleles of pawn have numerous morphological phenotypes, including dark deposits on the eye, truncated bristles, and semilethality. The gene encoding the pawn…”
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Characterization of two dominant alleles of the major rhodopsin-encoding gene ninaE in Drosophila
Published in Molecular vision (2011)“…In this study we investigated the biochemical and cell biologic characteristics of flies expressing two novel dominant alleles of the major rhodopsin encoding…”
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Loss of the phospholipase C gene product induces massive endocytosis of rhodopsin and arrestin in Drosophila photoreceptors
Published in Vision research (Oxford) (01-02-2002)“…Previously we have shown that a subset of visual transduction mutants in Drosophila melanogaster induce the formation of stable complexes between rhodopsin and…”
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Arrestin: roles in the life and death of retinal neurons
Published in The Neuroscientist (Baltimore, Md.) (01-08-2002)“…G protein-coupled receptors are a large family of signaling molecules that respond to a wide variety of extracellular stimuli. The receptors relay the…”
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Epitope masking of rhabdomeric rhodopsin during endocytosis-induced retinal degeneration
Published in Molecular vision (02-12-2002)“…To determine the fate of rhodopsin during endocytosis-mediated retinal degeneration. Drosophila stocks were raised in complete darkness and shifted to light…”
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Isolation of a novel visual-system-specific arrestin: an in vivo substrate for light-dependent phosphorylation
Published in Mechanisms of development (01-12-1990)“…Absorption of a photon of light by rhodopsin triggers mechanisms responsible for excitation as well as regulation of the phototransduction cascade. Arrestins…”
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