Search Results - "DOLOVICH, J"

Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements by Pizzichini, E, Pizzichini, M M, Efthimiadis, A, Evans, S, Morris, M M, Squillace, D, Gleich, G J, Dolovich, J, Hargreave, F E

“…Methods to examine sputum for indices of airway inflammation are evolving. We have examined the repeatability and the validity of an improved method to measure…”
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Measurement of inflammatory indices in induced sputum: effects of selection of sputum to minimize salivary contamination by Pizzichini, E, Pizzichini, MM, Efthimiadis, A, Hargreave, FE, Dolovich, J

“…Sputum examination is being used increasingly as a noninvasive method to assess airway inflammation. Expectorated sputum has variable contamination with…”
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Efficacy and tolerability of fluticasone propionate nasal drops 400 μg once daily compared with placebo for the treatment of bilateral polyposis in adults by Keith, P., Nieminen, J., Hollingworth, K., Dolovich, J.

“…Background Chronic eosinophilic rhinosinusitis underlies a range of respiratory disorders including nasal polyposis. Surgical and medical methods are used to…”
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Use of induced sputum cell counts to investigate airway inflammation in asthma by Pin, I, Gibson, P G, Kolendowicz, R, Girgis-Gabardo, A, Denburg, J A, Hargreave, F E, Dolovich, J

“…BACKGROUND: Airway inflammation is considered to be important in asthma but is relatively inaccessible to study. Less invasive methods of obtaining sputum from…”
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Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment by Pizzichini, M M, Pizzichini, E, Clelland, L, Efthimiadis, A, Mahony, J, Dolovich, J, Hargreave, F E

“…We have investigated the time-course of symptoms, forced expiratory volume in one second (FEV1), and the airway inflammatory changes in sputum selected from…”
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Diagnosing occupational asthma: use of induced sputum by Lemiere, C, Pizzichini, MM, Balkissoon, R, Clelland, L, Efthimiadis, A, O'Shaughnessy, D, Dolovich, J, Hargreave, FE

“…The diagnosis of occupational asthma (OA) needs to be made with as much objective evidence as possible. If there is airway inflammation, measurement of this…”
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Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared by Pizzichini, E, Pizzichini, MM, Kidney, JC, Efthimiadis, A, Hussack, P, Popov, T, Cox, G, Dolovich, J, O'Byrne, P, Hargreave, FE

“…Airway inflammation in asthma can be measured directly by invasive bronchoalveolar lavage (BAL), directly and relatively noninvasively by induced sputum and…”
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Prednisone-dependent asthma: inflammatory indices in induced sputum by Pizzichini, MM, Pizzichini, E, Clelland, L, Efthimiadis, A, Pavord, I, Dolovich, J, Hargreave, FE

“…The kinetics of changes in inflammatory indices in induced sputum from eight prednisone dependent asthmatics whose minimum clinical maintenance and…”
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Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils by TAKANASKI, S, NONAKA, R, ZHOU XING, O'BYRNE, P, DOLOVICH, J, JORDANA, M

“…In this study we have investigated the effects of interleukin 10 (IL-10) on human peripheral blood eosinophils stimulated with granulocyte/macrophage colony…”
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Exacerbations of asthma without sputum eosinophilia by Turner, M O, Hussack, P, Sears, M R, Dolovich, J, Hargreave, F E

“…BACKGROUND--Sputum analysis provides a non-invasive method of examining the airway secretions of subjects with asthma in order to better understand the…”
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Spontaneous and induced sputum to measure indices of airway inflammation in asthma by Pizzichini, M M, Popov, T A, Efthimiadis, A, Hussack, P, Evans, S, Pizzichini, E, Dolovich, J, Hargreave, F E

“…Inhalation of hypertonic saline to induce sputum may alter cells and fluid-phase markers in sputum. We have compared indices of inflammation in sputum produced…”
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Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils by Nonaka, M, Nonaka, R, Woolley, K, Adelroth, E, Miura, K, Okhawara, Y, Glibetic, M, Nakano, K, O'Byrne, P, Dolovich, J

“…Nasal polyposis and asthma are inflammatory conditions of the airways characterized by infiltration of activated inflammatory cells, particularly eosinophils…”
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Respiratory infections and the autumn increase in asthma morbidity by Dales, RE, Schweitzer, I, Toogood, JH, Drouin, M, Yang, W, Dolovich, J, Boulet, J

“…Unexplained autumn increases in hospital admissions for asthma have been reported in many countries, including the United States, Canada, England and Wales. To…”
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The evaluation of a cell dispersion method of sputum examination by Popov, T, Gottschalk, R, Kolendowicz, R, Dolovich, J, Powers, P, Hargreave, F E

“…In recent studies, sputum smear cell counts were found to be reproducible and usefully applied to research in asthma and other airway conditions. However, cell…”
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CD40 expression by human peripheral blood eosinophils by Ohkawara, Y, Lim, K G, Xing, Z, Glibetic, M, Nakano, K, Dolovich, J, Croitoru, K, Weller, P F, Jordana, M

“…In this study, we have investigated CD40 expression in human peripheral blood eosinophils and in human chronically inflamed nasal tissues, i.e., nasal polyps…”
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Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma by Ohno, I, Nitta, Y, Yamauchi, K, Hoshi, H, Honma, M, Woolley, K, O'Byrne, P, Dolovich, J, Jordana, M, Tamura, G

“…Tissue remodeling in bronchial tissues from asthmatics as well as in nasal polyp (NP) tissues includes sub-basement membrane deposition of collagen, stromal…”
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Some technical factors influencing the induction of sputum for cell analysis by Popov, TA, Pizzichini, MM, Pizzichini, E, Kolendowicz, R, Punthakee, Z, Dolovich, J, Hargreave, FE

“…Inhalation of hypertonic saline aerosol is a relatively noninvasive method to obtain sputum for examination of inflammatory processes in the airways. We…”
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Induced sputum cell and fluid-phase indices of inflammation: comparison of treatment with dithiothreitol vs phosphate-buffered saline by Efthimiadis, A, Pizzichini, MM, Pizzichini, E, Dolovich, J, Hargreave, FE

“…Treatment of sputum with dithiothreitol (DTT) gives reliable measurements of cellular and fluid-phase markers of airway inflammation. We investigated the…”
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Chronic cough with eosinophilic bronchitis: examination for variable airflow obstruction and response to corticosteroid by Gibson, P G, Hargreave, F E, Girgis-Gabardo, A, Morris, M, Denburg, J A, Dolovich, J

“…The purpose of this study was to examine airway responsiveness, sputum cells and the effects of inhaled corticosteroid in the chronic cough syndrome associated…”
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Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1) by Ohno, I, Lea, R G, Flanders, K C, Clark, D A, Banwatt, D, Dolovich, J, Denburg, J, Harley, C B, Gauldie, J, Jordana, M

“…Transforming growth factor beta (TGF beta) is a multifunctional protein which has been suggested to play a central role in the pathogenesis of chronic…”
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