Search Results - "DOLORES MAYAS, Maria"
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The obese healthy paradox: is inflammation the answer?
Published in Biochemical journal (15-08-2010)“…A paradoxical but common finding in the obesity clinic is the identification of individuals who can be considered 'inappropriately' healthy for their degree of…”
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Caspase Induction and BCL2 Inhibition in Human Adipose Tissue: A potential relationship with insulin signaling alteration
Published in Diabetes care (01-03-2013)“…Cell death determines the onset of obesity and associated insulin resistance. Here, we analyze the relationship among obesity, adipose tissue apoptosis, and…”
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3
Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation
Published in PloS one (24-10-2012)“…Obesity is associated with a low-grade chronic inflammation state. As a consequence, adipose tissue expresses pro-inflammatory cytokines that propagate…”
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Plasma renin–angiotensin system-regulating aminopeptidase activities are modified in early stage Alzheimer's disease and show gender differences but are not related to apolipoprotein E genotype
Published in Experimental gerontology (01-06-2013)“…Alterations in blood pressure and components of the renin–angiotensin system (RAS) contribute to the development and progression of Alzheimer's disease (AD),…”
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Neoadjuvant chemotherapy modifies serum angiotensinase activities in women with breast cancer
Published in Maturitas (01-05-2012)“…Abstract Purpose The aim of this study was to investigate the putative changes in serum angiotensinase activities (aminopeptidase N, APN; aminopeptidase B,…”
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VEGF Gene Expression in Adult Human Thymus Fat: A Correlative Study with Hypoxic Induced Factor and Cyclooxigenase-2
Published in PloS one (14-12-2009)“…It is well known that the adult human thymus degenerates into fat tissue; however, it has never been considered as a potential source of angiogenic factors…”
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Influence of chronic ethanol intake on mouse synaptosomal aspartyl aminopeptidase and aminopeptidase A: Relationship with oxidative stress indicators
Published in Alcohol (Fayetteville, N.Y.) (01-08-2012)“…Abstract Aminopeptidase A (APA) and aspartyl aminopeptidase (ASAP) not only act as neuromodulators in the regional brain renin-angiotensin system, but also…”
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Hypothalamus–pituitary–thyroid axis disruption in rats with breast cancer is related to an altered endogenous oxytocin/insulin-regulated aminopeptidase (IRAP) system
Published in Tumor biology (01-06-2011)“…Associations of breast cancer with diseases of the thyroid have been repeatedly reported, but the mechanism underlying this association remains to be…”
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9
Serum specific vasopressin-degrading activity is related to blood total cholesterol levels in men but not in women
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-07-2012)“…The role of vasopressin (AVP) in the pathophysiology of cardiovascular disease is controversial, but this peptide hormone is elevated in heart failure and some…”
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Glutathione Peroxidase gpx1 to gpx8 Genes Expression in Experimental Brain Tumors Reveals Gender-Dependent Patterns
Published in Genes (24-08-2023)“…Extensive research efforts in the field of brain tumor studies have led to the reclassification of tumors by the World Health Organization (WHO) and the…”
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Chronic ethanol intake modifies pyrrolidon carboxypeptidase activity in mouse frontal cortex synaptosomes under resting and K +-stimulated conditions: Role of calcium
Published in Neuroscience letters (04-07-2008)“…Pyrrolidon carboxypeptidase (Pcp) is an omega peptidase that removes pyroglutamyl N-terminal residues of peptides such as thyrotrophin-releasing hormone (TRH),…”
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12
Caspase Induction and BCL2 Inhibition in Human Adipose Tissue
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13
Phenolic compounds oleuropein and hydroxytyrosol exert differential effects on glioma development via antioxidant defense systems
Published in Journal of functional foods (01-11-2014)“…•Hydroxytyrosol inhibits tumor growth in experimental glioma.•Hydroxytyrosol decreases lipid peroxidation and protein oxidation.•Hydroxytyrosol restores…”
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Glutamyl- but Not Aspartyl- Aminopeptidase Activity is Modified in Serum of N-Methyl Nitrosourea-induced Rat Mammary Tumours
Published in Anticancer research (01-03-2004)“…Background: The rat model of breast cancer induced by the administration of N-methyl-nitrosourea (NMU) constitutes a useful tool for dissecting the initiation,…”
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15
Ethanol modifies differently aspartyl- and glutamyl-aminopeptidase activities in mouse frontal cortex synaptosomes
Published in Brain research bulletin (15-01-2002)“…Aminopeptidase A activity (aspartyl aminopeptidase (AspAP) and glutamyl aminopeptidase (GluAP) exerts angiotensinase activity due to its relation to the…”
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Influence of a fat overload on lipogenic regulators in metabolic syndrome patients
Published in British journal of nutrition (28-03-2011)“…Several epidemiological studies have related an increase of lipids in the postprandial state to an individual risk for the development of CVD, possibly due to…”
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Thymus fat as an attractive source of angiogenic factors in elderly subjects with myocardial ischemia
Published in AGE (01-08-2013)“…Aging negatively affects angiogenesis which is found to be linked to declined vascular endothelial growth factor (VEGF) production. Adult human thymus…”
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Mammary renin–angiotensin system-regulating aminopeptidase activities are modified in rats with breast cancer
Published in Tumor biology (01-12-2010)“…Angiotensin II in particular and/or the local renin–angiotensin system in general could have an important role in epithelial tissue growth and modelling;…”
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Renin-angiotensin System-regulating Aminopeptidases in Tumor Growth of Rat C6 Gliomas Implanted at the Subcutaneous Region
Published in Anticancer research (01-09-2012)“…Angiotensin peptides play roles in brain tumor infiltration and associated angiogenesis. We explored the roles of soluble and membrane-bound forms of…”
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Insulin-regulated Aminopeptidase/Placental Leucil Aminopeptidase (IRAP/P-LAP) and Angiotensin IV-forming Activities are Modified in Serum of Rats with Breast Cancer Induced by N-methyl-nitrosourea
Published in Anticancer research (01-03-2006)“…Background: In previous reports, changes in oxytocinase activity in human breast cancer tissue and in the serum of N-methyl-nitrosourea (NMU)-induced rat…”
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