Search Results - "DOLCETTI, Riccardo"
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Plasticity of Type I Interferon-Mediated Responses in Cancer Therapy: From Anti-tumor Immunity to Resistance
Published in Frontiers in oncology (21-08-2018)“…The efficacy of several therapeutic strategies against cancer, including cytotoxic drugs, radiotherapy, targeted immunotherapies and oncolytic viruses, depend…”
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2
A lymphomagenic role for HIV beyond immune suppression?
Published in Blood (17-03-2016)“…Despite the immune reconstitution promoted by combined antiretroviral therapy (cART), lymphomas still represent the most common type of cancer in HIV-infected…”
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3
Immunotherapy for Gastric Cancer: Time for a Personalized Approach?
Published in International journal of molecular sciences (29-05-2018)“…Over the last decade, our understanding of the mechanisms underlying immune modulation has greatly improved, allowing for the development of multiple…”
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4
Lymphomas occurring specifically in HIV-infected patients: From pathogenesis to pathology
Published in Seminars in cancer biology (01-12-2013)“…Abstract Lymphomas that develop in HIV positive patients are predominantly aggressive B-cell malignancies. The most common HIV-associated lymphomas are Burkitt…”
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Proposed Molecular and miRNA Classification of Gastric Cancer
Published in International journal of molecular sciences (06-06-2018)“…Gastric cancer (GC) is a common malignant neoplasm worldwide and one of the main cause of cancer-related deaths. Despite some advances in therapies, long-term…”
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Protein glycosylation in head and neck cancers: From diagnosis to treatment
Published in Biochimica et biophysica acta. Reviews on cancer (01-12-2020)“…Glycosylation is the most common post-translational modification (PTM) of proteins. Malignant tumour cells frequently undergo an alteration in surface protein…”
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Dissecting the Multiplicity of Immune Effects of Immunosuppressive Drugs to Better Predict the Risk of de novo Malignancies in Solid Organ Transplant Patients
Published in Frontiers in oncology (27-03-2019)“…malignancies constitute an emerging cause of morbidity after solid organ transplant (SOT), significantly affecting the long-term survival of transplant…”
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8
Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications
Published in Medicinal research reviews (01-03-2012)“…Telomerase is a ribonucleoprotein complex critically involved in extending and maintaining telomeres. Unlike the majority of somatic cells, in which hTERT and…”
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Editorial: Dendritic Cell-Based Immunotherapy in Solid and Haematologic Tumors
Published in Frontiers in immunology (31-03-2020)Get full text
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10
Local High-Dose Radiotherapy Induces Systemic Immunomodulating Effects of Potential Therapeutic Relevance in Oligometastatic Breast Cancer
Published in Frontiers in immunology (06-11-2017)“…Local irradiation of cancer through radiotherapy can induce spontaneous regression of non-directly irradiated lesions, suggesting the involvement of systemic…”
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Chlamydophila Psittaci Eradication With Doxycycline As First-Line Targeted Therapy for Ocular Adnexae Lymphoma: Final Results of an International Phase II Trial
Published in Journal of clinical oncology (20-08-2012)“…The pathogenic association between Chlamydophila psittaci (Cp) and ocular adnexal marginal zone lymphoma (OAMZL) and the efficacy of doxycycline monotherapy…”
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Virologic and immunologic evidence supporting an association between HHV-6 and Hashimoto's thyroiditis
Published in PLoS pathogens (01-10-2012)“…Hashimoto's thyroiditis (HT) is the most common of all thyroid diseases and is characterized by abundant lymphocyte infiltrate and thyroid impairment, caused…”
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13
Reverse immunoediting: when immunity is edited by Antigen
Published in Immunology letters (01-07-2016)“…Highlights • The immune response sculpts tumor features through the immunoediting process. • In “reverse immunoediting”, a tumor or a foreign antigen shapes…”
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14
Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (17-11-2015)“…Although in decline after successful anti-HIV therapy, B-cell lymphomas are still elevated in HIV-1-seropositive (HIV+) persons, and the mechanisms are…”
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15
Optimizing checkpoint inhibitors therapy for relapsed or progressive classic Hodgkin lymphoma by multiplex immunohistochemistry of the tumor microenvironment
Published in Cancer medicine (Malden, MA) (01-06-2019)“…Immune checkpoint‐blocking antibodies have therapeutic activity against relapsed or progressive classic Hodgkin lymphoma (cHL), but Hodgkin Reed‐Sternberg…”
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B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation
Published in Cancer gene therapy (01-06-2021)“…Combined antiretroviral therapy (cART) for HIV-1 dramatically slows disease progression among HIV + individuals. Currently, lymphoma represents the main cause…”
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The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy - results from the AGITG DOCTOR trial and the cancer evolution biobank
Published in Frontiers in immunology (12-10-2023)“…A plateau in treatment effect can be seen for the current 'one-size-fits-all' approach to oesophageal adenocarcinoma (OAC) management using neoadjuvant…”
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Multiparametric flow cytometry to characterize vaccine-induced polyfunctional T cell responses and T cell/NK cell exhaustion and memory phenotypes in mouse immuno-oncology models
Published in Frontiers in immunology (06-04-2023)“…Suitable methods to assess immunogenicity and therapeutic efficacy of cancer vaccines in preclinical cancer models are critical to overcome current limitations…”
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Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapies
Published in Oncotarget (30-08-2016)“…In recent years, recurrent somatic mutations in epigenetic regulators have been identified in patients with hematological malignancies. Furthermore,…”
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Toll-Like Receptor 1/2 and 5 Ligands Enhance the Expression of Cyclin D1 and D3 and Induce Proliferation in Mantle Cell Lymphoma
Published in PloS one (28-04-2016)“…Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin's lymphoma with a still undefined etiology. Several lines of evidence are consistent with the…”
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